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If a protein meets these conditions... i

Common conditions

Special conditions

  • Matches PIRSR SRHMM628472-1 Subsequence at position 276 - 276 aligns to "D" in entry O00167 (applies "Proton donor") Subsequence at position 274 - 274 aligns to "D" in entry O00167 (applies "Nucleophile")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei

  • Proton donor (to residues corresponding to position 276)
  • Nucleophile (to residues corresponding to position 274)
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