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If a protein meets these conditions... i

Common conditions

Special conditions

    • Predicted signal

... then these annotations are applied i

Protein namei

  • Recommended name:
    Pro-interleukin-16

Cleaved chain(s) or included domain(s)i

  • Cleaved chain:
    Recommended name:
    Interleukin-16
    Short name:
    IL-16
    Alternative name(s):
    Lymphocyte chemoattractant factor
    Short name:
    LCF

Gene namei

  • Name:IL16

Functioni

  • Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.

Subcellular locationi

Subunit structurei

  • Homotetramer.

Chaini

  • @CHAIN_NAME@i (to residues corresponding to positions @TO|+1@i - @CTER@i)

Signal peptidei

  • (to residues corresponding to positions @NTER@i - @TO@i)

Keywordsi

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