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The annotation and conditions in this rule are derived from the following entries: Q9Y3D8 (KAD6_HUMAN), Q09527 (KAD6_CAEEL), Q7JYV7 (KAD6_DROME)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00039
    • taxon = Eukaryota
    • fragment ≠ the sequence is fragmented

Special conditions

    • taxon = Vertebrata
    • Subsequence at position 148 - 149 aligns to "[KE]-P" in entry Q9Y3D8
    • Subsequence at position 79 - 79 aligns to "H" in entry Q9Y3D8 (individually applies "ATP")
    • Subsequence at position 108 - 118 aligns to entry Q9Y3D8 (individually applies "LID")
    • Subsequence at position 109 - 109 aligns to "R" in entry Q9Y3D8 (individually applies "ATP")
    • Subsequence at position 39 - 39 aligns to "[RK]" in entry Q9Y3D8 (individually applies "AMP")
    • Subsequence at position 105 - 105 aligns to "R" in entry Q9Y3D8 (individually applies "ATP")
    • Subsequence at position 33 - 56 aligns to entry Q9Y3D8 (individually applies "NMPbind")
    • Subsequence at position 13 - 18 aligns to "G-x-G-K-[ST]-[ST]" in entry Q9Y3D8 (individually applies "ATP")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi

  • Recommended name:
    Adenylate kinase isoenzyme 6 (EC:2.7.4.3)
    Short name:
    AK6
    Alternative name(s):
    Coilin-interacting nuclear ATPase protein
    Dual activity adenylate kinase/ATPase
    Short name:
    AK/ATPase
  • Recommended name:
    Adenylate kinase isoenzyme 6 homolog (EC:2.7.4.3)
    Short name:
    AK6
    Alternative name(s):
    Dual activity adenylate kinase/ATPase
    Short name:
    AK/ATPase

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:AK6, Synonym:CINAP

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

  • Monomer and homodimer. Interacts with COIL (via C-terminus).
  • Monomer and homodimer.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
  • Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
  • Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity.
  • Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi

  • ATP (to residues corresponding to positions 148 - 149)
  • ATP (to residues corresponding to positions 13 - 18)

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei

  • ATP (to residues corresponding to position 79)
  • ATP (to residues corresponding to position 109)
  • AMP (to residues corresponding to position 39)
  • ATP (to residues corresponding to position 105)

<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni

  • LID (to residues corresponding to positions 108 - 118)
  • NMPbind (to residues corresponding to positions 33 - 56)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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