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The annotation and conditions in this rule are derived from the following entries: P60340 (TRUB_ECOLI), P9WHP7 (TRUB_MYCTU), Q9WZW0 (TRUB_THEMA)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_01080
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

Special conditions

    • Subsequence at position 48 - 48 aligns to "D" in entry P60340
    • taxon = Enterobacterales
    • Subsequence at position 43 - 43 aligns to "H" in entry P60340 (individually applies "Substrate")
    • Subsequence at position 76 - 76 aligns to "Y" in entry P60340 (individually applies "Substrate")
    • Subsequence at position 179 - 179 aligns to "Y" in entry P60340 (individually applies "Substrate")
    • Subsequence at position 200 - 200 aligns to "L" in entry P60340 (individually applies "Substrate")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namei

  • Recommended name:
    tRNA pseudouridine synthase B (EC:5.4.99.25)
    Alternative name(s):
    tRNA pseudouridine(55) synthase
    Short name:
    Psi55 synthase
    tRNA pseudouridylate synthase
    tRNA-uridine isomerase

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:truB

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei

  • Substrate (to residues corresponding to position 43)
  • Substrate (to residues corresponding to position 76)
  • Substrate (to residues corresponding to position 179)
  • Substrate (to residues corresponding to position 200)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei

  • Nucleophile (to residues corresponding to position 48)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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