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The annotation and conditions in this rule are derived from the following entries: P00864 (CAPP_ECOLI), Q59757 (CAPP_RHOMR)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00595
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

Special conditions

    • Subsequence at position 138 - 138 aligns to "H" in entry P00864 (individually applies "")
    • Subsequence at position 546 - 546 aligns to "K" in entry P00864 (individually applies "")

... then these annotations are applied i

Protein namei

  • Recommended name:
    Phosphoenolpyruvate carboxylase (EC:
    Short name:
    Short name:

Gene namei

  • Name:ppc

Subunit structurei

  • Homotetramer.

Catalytic activityi

  • Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.

Sequence similaritiesi



  • Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

Active sitei

  • (to residues corresponding to position 138)
  • (to residues corresponding to position 546)


GO (Gene Ontology) termsi

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