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The annotation and conditions in this rule are derived from the following entries: P22259 (PCKA_ECOLI), A6VKV4 (PCKA_ACTSZ), O09460 (PCKA_ANASU), Q5SLL5 (PCKA_THET8)

If a protein meets these conditions... i

Common conditions

Special conditions

    • Subsequence at position 333 - 333 aligns to "R" in entry P22259 (individually applies "Substrate")
    • Subsequence at position 449 - 450 aligns to "[RK]-[IV]" in entry P22259 (individually applies "ATP")
    • Subsequence at position 297 - 297 aligns to "[ED]" in entry P22259 (individually applies "ATP")
    • Subsequence at position 213 - 213 aligns to "K" in entry P22259 (individually applies "Manganese")
    • Subsequence at position 232 - 232 aligns to "H" in entry P22259 (individually applies "Manganese; via tele nitrogen")
    • Subsequence at position 65 - 65 aligns to "R" in entry P22259 (individually applies "Substrate")
    • Subsequence at position 248 - 256 aligns to "G-L-S-G-T-G-K-T-T" in entry P22259 (individually applies "ATP")
    • Subsequence at position 333 - 333 aligns to "R" in entry P22259 (individually applies "ATP")
    • Subsequence at position 455 - 455 aligns to "[TS]" in entry P22259 (individually applies "ATP")
    • Subsequence at position 207 - 207 aligns to "[YF]" in entry P22259 (individually applies "Substrate")
    • Subsequence at position 232 - 232 aligns to "H" in entry P22259 (individually applies "ATP")
    • Subsequence at position 269 - 269 aligns to "D" in entry P22259 (individually applies "Manganese")
    • Subsequence at position 213 - 213 aligns to "K" in entry P22259 (individually applies "Substrate")
    • Subsequence at position 213 - 213 aligns to "K" in entry P22259 (individually applies "ATP")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namei

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:pckA

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

  • Monomer.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi

  • Pathwayi: gluconeogenesis

    This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.
    View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei

  • Substrate (to residues corresponding to position 333)
  • ATP (to residues corresponding to position 297)
  • Substrate (to residues corresponding to position 65)
  • ATP (to residues corresponding to position 333)
  • ATP (to residues corresponding to position 455)
  • Substrate (to residues corresponding to position 207)
  • ATP (to residues corresponding to position 232)
  • Substrate (to residues corresponding to position 213)
  • ATP (to residues corresponding to position 213)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi

  • ATP (to residues corresponding to positions 449 - 450)
  • ATP (to residues corresponding to positions 248 - 256)

<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei

  • N6-acetyllysine (to residues corresponding to position 87)
  • N6-acetyllysine (to residues corresponding to position 523)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi

  • Manganese (to residues corresponding to position 213)
  • Manganese; via tele nitrogen (to residues corresponding to position 232)
  • Manganese (to residues corresponding to position 269)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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