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The annotation and conditions in this rule are derived from the following entries: P61998 (TF2B_PYRFU), P61999 (TF2B_PYRWO)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00383
    • taxon = Archaea
    • fragment ≠ the sequence is fragmented

Special conditions

    • Subsequence at position 7 - 7 aligns to "C" in entry P61998 Subsequence at position 29 - 29 aligns to "C" in entry P61998 Subsequence at position 26 - 26 aligns to "C" in entry P61998 Subsequence at position 10 - 10 aligns to "C" in entry P61998
    • Subsequence at position 210 - 291 aligns to entry P61998 (individually applies "2")
    • Subsequence at position 114 - 197 aligns to entry P61998 (individually applies "1")
  • Subsequence at position 7 - 7 aligns to "C" in entry P61998 (applies "Zinc") Subsequence at position 29 - 29 aligns to "C" in entry P61998 (applies "Zinc") Subsequence at position 26 - 26 aligns to "C" in entry P61998 (applies "Zinc") Subsequence at position 10 - 10 aligns to "C" in entry P61998 (applies "Zinc")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namei

  • Recommended name:
    Transcription initiation factor IIB
    Short name:
    TFIIB

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:tfb

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati

  • 2 (to residues corresponding to positions 210 - 291)
  • 1 (to residues corresponding to positions 114 - 197)

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi

  • Zinc (to residues corresponding to position 7)
  • Zinc (to residues corresponding to position 29)
  • Zinc (to residues corresponding to position 26)
  • Zinc (to residues corresponding to position 10)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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