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The annotation and conditions in this rule are derived from the following entries: O87405 (GLSA_RHIEC), O31465 (GLSA1_BACSU)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00313
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

Special conditions

    • Subsequence at position 74 - 74 aligns to "S" in entry O31465
    • Subsequence at position 74 - 74 aligns to "S" in entry O31465
    • Subsequence at position 126 - 126 aligns to "N" in entry O31465 (individually applies "Substrate")
    • Subsequence at position 170 - 170 aligns to "E" in entry O31465 (individually applies "Substrate")
    • Subsequence at position 177 - 177 aligns to "N" in entry O31465 (individually applies "Substrate")
    • Subsequence at position 201 - 201 aligns to "Y" in entry O31465 (individually applies "Substrate")
    • Subsequence at position 253 - 253 aligns to "Y" in entry O31465 (individually applies "Substrate")
    • Subsequence at position 271 - 271 aligns to "V" in entry O31465 (individually applies "Substrate; via amide nitrogen")

... then these annotations are applied i

Protein namei

  • Recommended name:
    Glutaminase (EC:3.5.1.2)

Gene namei

  • Name:glsA

Sequence similaritiesi

Subunit structurei

  • Homotetramer.

Catalytic activityi

  • L-glutamine + H2O = L-glutamate + NH3.

Modified residuei

  • N6-acetyllysine (to residues corresponding to position 294)

Binding sitei

  • Substrate (to residues corresponding to position 74)
  • Substrate (to residues corresponding to position 126)
  • Substrate (to residues corresponding to position 170)
  • Substrate (to residues corresponding to position 177)
  • Substrate (to residues corresponding to position 201)
  • Substrate (to residues corresponding to position 253)
  • Substrate; via amide nitrogen (to residues corresponding to position 271)

Keywordsi

GO (Gene Ontology) termi

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