Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

The annotation and conditions in this rule are derived from the following entries: P04766 (IF2_GEOSE), P0A705 (IF2_ECOLI), P48515 (IF2_THET8), Q9HNQ2 (IF2P_HALSA), O26359 (IF2P_METTH)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00100_B
    • gene location = Plastid; Chloroplast
    • fragment ≠ the sequence is fragmented
    • Matches HAMAP signature MF_00100_A
    • taxon = Archaea
    • fragment ≠ the sequence is fragmented

Special conditions

    • gene location = Plastid; Chloroplast
    • taxon = Bacteria
    • Subsequence at position 398 - 405 aligns to "G-H-V-D-H-G-K-T" in entry P0A705 (individually applies "GTP")
    • Subsequence at position 444 - 448 aligns to "D-T-P-G-H" in entry P0A705 (individually applies "GTP")
    • Subsequence at position 392 - 540 aligns to entry P0A705 (individually applies "G-domain")
    • Subsequence at position 498 - 501 aligns to "[NST]-K-[LIVCMT]-D" in entry P0A705 (individually applies "GTP")
    • gene location = Plastid; Chloroplast
    • Subsequence at position 398 - 405 aligns to "G-H-V-D-H-G-K-T" in entry P0A705 (individually applies "GTP")
    • Subsequence at position 444 - 448 aligns to "D-T-P-G-H" in entry P0A705 (individually applies "GTP")
    • Subsequence at position 392 - 540 aligns to entry P0A705 (individually applies "G-domain")
    • Subsequence at position 498 - 501 aligns to "[NST]-K-[LIVCMT]-D" in entry P0A705 (individually applies "GTP")
    • taxon = Archaea
    • Subsequence at position 12 - 19 aligns to "G-H-V-D-[HVA]-G-K-T" in entry O26359 (individually applies "GTP")
    • Subsequence at position 76 - 80 aligns to "D-T-P-G-H" in entry O26359 (individually applies "GTP")
    • Subsequence at position 130 - 133 aligns to "[NT]-K-[LIV]-D" in entry O26359 (individually applies "GTP")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi

  • Recommended name:
    Translation initiation factor IF-2, chloroplastic
  • Recommended name:
    Probable translation initiation factor IF-2
  • Recommended name:
    Translation initiation factor IF-2

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:infB

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
  • Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  • One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni

  • G-domain (to residues corresponding to positions 392 - 540)
  • G-domain (to residues corresponding to positions 392 - 540)

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi

  • GTP (to residues corresponding to positions 398 - 405)
  • GTP (to residues corresponding to positions 444 - 448)
  • GTP (to residues corresponding to positions 498 - 501)
  • GTP (to residues corresponding to positions 398 - 405)
  • GTP (to residues corresponding to positions 444 - 448)
  • GTP (to residues corresponding to positions 498 - 501)
  • GTP (to residues corresponding to positions 12 - 19)
  • GTP (to residues corresponding to positions 76 - 80)
  • GTP (to residues corresponding to positions 130 - 133)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again