UniRule: UR000054575
Source Rule HAMAP: MF_01463
The annotation and conditions in this rule are derived from the following entries: P0AG90 (SECD_ECOLI), Q5SKE6 (SECDF_THET8), E9RGS3 (SECD_VIBAL), D4GTK5 (SECD_HALVD), O32047 (SECDF_BACSU)
If a protein meets these conditions... i
Common conditions
- Matches HAMAP signature MF_01463_B
- taxon = Bacteria
- fragment ≠ the sequence is fragmented
- Matches HAMAP signature MF_01463_A
- taxon = Archaea
- fragment ≠ the sequence is fragmented
Special conditions
- taxon = Archaea
- taxon = Bacteria
- taxon = Proteobacteria
- proteome property = Membrane=2
- taxon = Bacteria
- taxon ≠ Proteobacteria
- taxon = Cyanobacteria
- taxon ≠ Gloeobacter
- proteome property = Membrane=1
- proteome property ≠ Membrane=*
- Predicted transmembrane
... then these annotations are applied i
Protein namesi
- Recommended name:Protein-export membrane protein SecD
- Recommended name:Protein translocase subunit SecD
Gene namei
- Name:secD
Sequence similaritiesi
- Belongs to the SecD/SecF family. SecD subfamily.
Subcellular locationi
Functioni
- Involved in protein export.
- Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
- Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
Subunit structurei
- Part of the protein translocation apparatus. Forms a complex with SecF.
- Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
- Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
Transmembranei
- Helical (to residues corresponding to positions @FROM@i - @TO@i)
Keywordsi
- Cell membrane
- Membrane
- Protein transport
- Translocation
- Transmembrane
- Transmembrane helix
- Transport
- Cell inner membrane
GO (Gene Ontology) termsi
- GO:0005886 plasma membrane
- GO:0006605 protein targeting
- GO:0065002 intracellular protein transmembrane transport
- GO:0043952 protein transport by the Sec complex