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The annotation and conditions in this rule are derived from the following entries: P0A6D3 (AROA_ECOLI), P9WPY5 (AROA_MYCTU), Q9R4E4 (AROA_AGRSC), Q83E11 (AROA_COXBU), Q9S400 (AROA_STRPN), Q9KRB0 (AROA_VIBCH)

If a protein meets these conditions... i

Common conditions

Special conditions

    • Subsequence at position 22 - 23 aligns to "K-S" in entry P0A6D3 (individually applies "Shikimate-3-phosphate binding")
    • Subsequence at position 27 - 27 aligns to "R" in entry P0A6D3 (individually applies "Shikimate-3-phosphate")
    • Subsequence at position 336 - 336 aligns to "[NQ]" in entry P0A6D3 (individually applies "Shikimate-3-phosphate")
    • Subsequence at position 94 - 97 aligns to "[LNAGDEQS]-x-[GA]-[TSIAV]" in entry P0A6D3 (individually applies "Phosphoenolpyruvate")
    • Subsequence at position 386 - 386 aligns to "R" in entry P0A6D3 (individually applies "Phosphoenolpyruvate")
    • Subsequence at position 169 - 171 aligns to "[ST]-[ST]-[QN]" in entry P0A6D3 (individually applies "Shikimate-3-phosphate binding")
    • Subsequence at position 124 - 124 aligns to "R" in entry P0A6D3 (individually applies "Phosphoenolpyruvate")
    • Subsequence at position 313 - 313 aligns to "[DE]" in entry P0A6D3 (individually applies "Proton acceptor")
    • Subsequence at position 411 - 411 aligns to "[KQ]" in entry P0A6D3 (individually applies "Phosphoenolpyruvate")
    • Subsequence at position 344 - 344 aligns to "R" in entry P0A6D3 (individually applies "Phosphoenolpyruvate")
    • Subsequence at position 340 - 340 aligns to "[KQ]" in entry P0A6D3 (individually applies "Shikimate-3-phosphate")
    • Subsequence at position 341 - 341 aligns to "E" in entry P0A6D3 (individually applies "Proton donor")
    • Subsequence at position 197 - 197 aligns to "[ST]" in entry P0A6D3 (individually applies "Shikimate-3-phosphate")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namei

  • Recommended name:
    3-phosphoshikimate 1-carboxyvinyltransferase (EC:2.5.1.19)
    Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate synthase
    Short name:
    EPSP synthase
    Short name:
    EPSPS

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:aroA

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

  • Monomer.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi

<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni

  • Shikimate-3-phosphate binding (to residues corresponding to positions 22 - 23)
  • Phosphoenolpyruvate (to residues corresponding to positions 94 - 97)
  • Shikimate-3-phosphate binding (to residues corresponding to positions 169 - 171)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei

  • Shikimate-3-phosphate (to residues corresponding to position 27)
  • Shikimate-3-phosphate (to residues corresponding to position 336)
  • Phosphoenolpyruvate (to residues corresponding to position 386)
  • Phosphoenolpyruvate (to residues corresponding to position 124)
  • Phosphoenolpyruvate (to residues corresponding to position 411)
  • Phosphoenolpyruvate (to residues corresponding to position 344)
  • Shikimate-3-phosphate (to residues corresponding to position 340)
  • Shikimate-3-phosphate (to residues corresponding to position 197)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei

  • Proton acceptor (to residues corresponding to position 313)
  • Proton donor (to residues corresponding to position 341)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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