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The annotation and conditions in this rule are derived from the following entries: P28248 (DCD_ECOLI), Q57872 (DCDB_METJA), P9WP17 (DCDB_MYCTU), Q9KFV3 (DCDB_BACHD)

If a protein meets these conditions... i

Common conditions

Special conditions

    • Subsequence at position 148 - 148 aligns to "Q" in entry P9WP17
    • Subsequence at position 116 - 117 aligns to "G-[FWY]" in entry P9WP17
    • Subsequence at position 148 - 148 does not align to "Q" in entry P9WP17
    • Subsequence at position 116 - 117 does not align to "G-[FWY]" in entry P9WP17
    • Subsequence at position 148 - 148 aligns to "Q" in entry P9WP17
    • Subsequence at position 116 - 117 aligns to "G-[FWY]" in entry P9WP17
    • Subsequence at position 101 - 106 aligns to "[KR]-S-[ST]-x-[GA]-R" in entry P9WP17 (individually applies "dCTP binding")
    • Subsequence at position 129 - 129 aligns to "E" in entry P9WP17 (individually applies "Proton donor/acceptor")
    • Subsequence at position 119 - 119 aligns to "D" in entry P9WP17 (individually applies "dCTP")
    • Subsequence at position 174 - 174 aligns to "Q" in entry P9WP17 (individually applies "dCTP")
    • Subsequence at position 127 - 129 aligns to "[TV]-L-E" in entry P9WP17 (individually applies "dCTP binding")
    • Subsequence at position 162 - 162 aligns to "Y" in entry P9WP17 (individually applies "dCTP")
    • Subsequence at position 170 - 170 aligns to "K" in entry P9WP17 (individually applies "dCTP")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:dcd

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
  • Catalyzes the deamination of dCTP to dUTP.

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

  • Homotrimer.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi

  • Pathwayi: dUMP biosynthesis

    This protein is involved in step 1 of the subpathway that synthesizes dUMP from dCTP. This subpathway is part of the pathway dUMP biosynthesis, which is itself part of Pyrimidine metabolism.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes dUMP from dCTP, the pathway dUMP biosynthesis and in Pyrimidine metabolism.
  • Pathwayi: dUMP biosynthesis

    This protein is involved in step 1 of the subpathway that synthesizes dUMP from dCTP (dUTP route). This subpathway is part of the pathway dUMP biosynthesis, which is itself part of Pyrimidine metabolism.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes dUMP from dCTP (dUTP route), the pathway dUMP biosynthesis and in Pyrimidine metabolism.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi

  • dCTP binding (to residues corresponding to positions 101 - 106)
  • dCTP binding (to residues corresponding to positions 127 - 129)

<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei

  • Important for bifunctional activity (to residues corresponding to positions 116 - 117)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei

  • Proton donor/acceptor (to residues corresponding to position 129)

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei

  • dCTP (to residues corresponding to position 148)
  • dCTP (to residues corresponding to position 119)
  • dCTP (to residues corresponding to position 174)
  • dCTP (to residues corresponding to position 162)
  • dCTP (to residues corresponding to position 170)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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