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The annotation and conditions in this rule are derived from the following entries: P22634 (MURI_ECOLI), P56868 (MURI_AQUPY), P94556 (MURI1_BACSU), Q836J0 (MURI_ENTFA), Q9ZLT0 (MURI_HELPJ), Q03469 (MURI_LACFE), Q9A1B7 (MURI_STRP1)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00258
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

Special conditions

    • Subsequence at position 60 - 61 aligns to "[YF]-[GS]" in entry P22634 (individually applies "Substrate binding")
    • Subsequence at position 28 - 29 aligns to "D-S" in entry P22634 (individually applies "Substrate binding")
    • Subsequence at position 205 - 206 aligns to "T-H" in entry P22634 (individually applies "Substrate binding")
    • Subsequence at position 204 - 204 aligns to "C" in entry P22634 (individually applies "Proton donor/acceptor")
    • Subsequence at position 93 - 94 aligns to "N-[TS]" in entry P22634 (individually applies "Substrate binding")
    • Subsequence at position 92 - 92 aligns to "C" in entry P22634 (individually applies "Proton donor/acceptor")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namei

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:murI

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi

  • Pathwayi: peptidoglycan biosynthesis

    This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.
    View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Provides the (R)-glutamate required for cell wall biosynthesis.

<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni

  • Substrate binding (to residues corresponding to positions 60 - 61)
  • Substrate binding (to residues corresponding to positions 28 - 29)
  • Substrate binding (to residues corresponding to positions 205 - 206)
  • Substrate binding (to residues corresponding to positions 93 - 94)

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei

  • Proton donor/acceptor (to residues corresponding to position 204)
  • Proton donor/acceptor (to residues corresponding to position 92)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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