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The annotation and conditions in this rule are derived from the following entries: Q9UWW1 (PRIL_SACS2), Q8U4H7 (PRIL_PYRFU), O57935 (PRIL_PYRHO), Q5JJ73 (PRIL_THEKO), Q9V291 (PRIL_PYRAB)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00701
    • taxon = Archaea
    • fragment ≠ the sequence is fragmented

Special conditions

    • Subsequence at position 216 - 216 aligns to "C" in entry Q9UWW1 Subsequence at position 293 - 293 aligns to "C" in entry Q9UWW1 Subsequence at position 280 - 280 aligns to "C" in entry Q9UWW1 Subsequence at position 289 - 289 aligns to "C" in entry Q9UWW1
  • Subsequence at position 216 - 216 aligns to "C" in entry Q9UWW1 (applies "Iron-sulfur (4Fe-4S)") Subsequence at position 293 - 293 aligns to "C" in entry Q9UWW1 (applies "Iron-sulfur (4Fe-4S)") Subsequence at position 280 - 280 aligns to "C" in entry Q9UWW1 (applies "Iron-sulfur (4Fe-4S)") Subsequence at position 289 - 289 aligns to "C" in entry Q9UWW1 (applies "Iron-sulfur (4Fe-4S)")

... then these annotations are applied i

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namei

  • Recommended name:
    DNA primase large subunit PriL

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namei

  • Name:priL

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

  • Heterodimer of a small subunit (PriS) and a large subunit (PriL).

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> describes the function(s) of a protein.<p><a href='/help/function' target='_top'>More...</a></p>Functioni

  • Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi

  • Iron-sulfur (4Fe-4S) (to residues corresponding to position 216)
  • Iron-sulfur (4Fe-4S) (to residues corresponding to position 293)
  • Iron-sulfur (4Fe-4S) (to residues corresponding to position 280)
  • Iron-sulfur (4Fe-4S) (to residues corresponding to position 289)

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO (Gene Ontology) termsi

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