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The annotation and conditions in this rule are derived from the following entries: P23494 (LACA_LACLL)

If a protein meets these conditions... i

Common conditions

... then these annotations are applied i

Protein namei

  • Recommended name:
    Galactose-6-phosphate isomerase subunit LacA (EC:

Gene namei

  • Name:lacA

Subunit structurei

  • Heteromultimeric protein consisting of LacA and LacB.


  • Pathwayi: D-galactose 6-phosphate degradation

    This protein is involved in step 1 of the subpathway that synthesizes D-tagatose 6-phosphate from D-galactose 6-phosphate. This subpathway is part of the pathway D-galactose 6-phosphate degradation, which is itself part of Carbohydrate metabolism.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-tagatose 6-phosphate from D-galactose 6-phosphate, the pathway D-galactose 6-phosphate degradation and in Carbohydrate metabolism.

Catalytic activityi

  • D-galactose 6-phosphate = D-tagatose 6-phosphate.

Sequence similaritiesi


GO (Gene Ontology) termsi

  • GO:0019512 lactose catabolic process via tagatose-6-phosphate
  • GO:0050044 galactose-6-phosphate isomerase activity

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