Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

The annotation and conditions in this rule are derived from the following entries: P07862 (DDLB_ECOLI), P0A6J8 (DDLA_ECOLI)

If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00047
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

... then these annotations are applied i

Protein namei

  • Recommended name:
    D-alanine--D-alanine ligase (EC:
    Alternative name(s):
    D-alanylalanine synthetase
    D-Ala-D-Ala ligase

Gene namei

  • Name:ddl

Catalytic activityi

  • ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.


  • Pathwayi: peptidoglycan biosynthesis

    This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.
    View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.


  • Cell wall formation.

Sequence similaritiesi

Subcellular locationi


GO (Gene Ontology) termsi

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again