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Protein
Submitted name:

Transcription termination factor 2

Gene

TTF2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription termination factor 2Imported
Gene namesi
Name:TTF2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000116830.11
HGNCiHGNC:12398 TTF2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000116830

PTM / Processingi

Proteomic databases

MaxQBiX6RI15
PeptideAtlasiX6RI15
PRIDEiX6RI15

Expressioni

Gene expression databases

BgeeiENSG00000116830 Expressed in 184 organ(s), highest expression level in corpus callosum
ExpressionAtlasiX6RI15 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliX6RI15
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 138Helicase C-terminalInterPro annotationAdd BLAST138

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili100 – 120Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410INU3 Eukaryota
ENOG410XPDU LUCA
GeneTreeiENSGT00910000144263

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51194 HELICASE_CTER, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

X6RI15-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
NMLKVVALHL KKHGLTYATI DGSVNPKQRM DLVEAFNHSR GPQVMLISLL
60 70 80 90 100
AGGVGLNLTG GNHLFLLDMH WNPSLEDQAC DRIYRVGQQK DVVIHRFVCE
110 120 130 140
GTVEEKILQL QEKKKDLAKQ VLSGSGESVT KLTLADLRVL FGI
Length:143
Mass (Da):15,857
Last modified:June 11, 2014 - v1
Checksum:iA811C410B7345235
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UNY4TTF2_HUMAN
Transcription termination factor 2
TTF2
1,162Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139248 Genomic DNA No translation available.
AL391476 Genomic DNA No translation available.
AL445231 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000427271; ENSP00000408111; ENSG00000116830
UCSCiuc057jtd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139248 Genomic DNA No translation available.
AL391476 Genomic DNA No translation available.
AL445231 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliX6RI15
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiX6RI15
PeptideAtlasiX6RI15
PRIDEiX6RI15

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000427271; ENSP00000408111; ENSG00000116830
UCSCiuc057jtd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000116830.11
HGNCiHGNC:12398 TTF2
OpenTargetsiENSG00000116830
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410INU3 Eukaryota
ENOG410XPDU LUCA
GeneTreeiENSGT00910000144263

Miscellaneous databases

ChiTaRSiTTF2 human

Gene expression databases

BgeeiENSG00000116830 Expressed in 184 organ(s), highest expression level in corpus callosum
ExpressionAtlasiX6RI15 baseline and differential

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51194 HELICASE_CTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiX6RI15_HUMAN
AccessioniPrimary (citable) accession number: X6RI15
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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