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Protein
Submitted name:

Rab11 family-interacting protein 3

Gene

RAB11FIP3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Rab11 family-interacting protein 3Imported
Gene namesi
Name:RAB11FIP3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000090565.15
HGNCiHGNC:17224 RAB11FIP3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000090565

PTM / Processingi

Proteomic databases

PRIDEiX6RFI8

Expressioni

Gene expression databases

BgeeiENSG00000090565 Expressed in 207 organ(s), highest expression level in cortex of kidney
ExpressionAtlasiX6RFI8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliX6RFI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 113EF-handInterPro annotationAdd BLAST36
Domaini120 – 145EF-handInterPro annotationAdd BLAST26
Domaini615 – 677FIP-RBDInterPro annotationAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili322 – 342Sequence analysisAdd BLAST21
Coiled coili408 – 435Sequence analysisAdd BLAST28
Coiled coili455 – 524Sequence analysisAdd BLAST70
Coiled coili529 – 563Sequence analysisAdd BLAST35
Coiled coili581 – 615Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00440000033742

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR037245 FIP-RBD_C_sf
IPR019018 Rab-bd_FIP-RBD
IPR032920 Rab11-FIP3
PANTHERiPTHR15726:SF6 PTHR15726:SF6, 1 hit
PfamiView protein in Pfam
PF09457 RBD-FIP, 1 hit
SUPFAMiSSF144270 SSF144270, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 2 hits
PS51511 FIP_RBD, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

X6RFI8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
WTEEPEECGP ASCPESAPFR LQGSSSSHRA RGEVDVFSPF PAPTAGELAL
60 70 80 90 100
EQGPGSPPQP SDLSQTHPLP SEPVGSQEDG PRLRAVFDAL DGDGDGFVRI
110 120 130 140 150
EDFIQFATVY GAEQVKDLTK YLDPSGLGVI SFEDFYQGIT AIRNGDPDGQ
160 170 180 190 200
CYGGVASAQD EEPLACPDEF DDFVTYEANE VTDSAYMGSE STYSECETFT
210 220 230 240 250
DEDTSTLVHP ELQPEGDADS AGGSAVPSEC LDAMEEPDHG ALLLLPGRPH
260 270 280 290 300
PHGQSVITVI GGEEHFEDYG EGSEAELSPE TLCNGQLGCS DPAFLTPSTD
310 320 330 340 350
PLAAKLHSIL TDEAFEFYCS QCHKQINRLE DLSARLSDLE MNSPTKRLSS
360 370 380 390 400
KKVARYLHQS GALTMEALED PSPELMEGPE EDIADKVVFL ERRVLELEKD
410 420 430 440 450
TAATGEQHSR LRQENLQLVH RANALEEQLK EQELRACEMV LEETRRQKEL
460 470 480 490 500
LCKMEREKSI EIENLQTRLQ QLDEENSELR SCTPCLKANI ERLEEEKQKL
510 520 530 540 550
LDEIESLTLR LSEEQENKRR MGDRLSHERH QFQRDKEATQ ELIEDLRKQL
560 570 580 590 600
EHLQLLKLEA EQRRGRSSSM GLQEYHSRAR ESELEQEVRR LKQDNRNLKE
610 620 630 640 650
QNEELNGQII TLSIQGAKSL FSTAFSESLA AEISSVSRDE LMEAIQKQEE
660 670
INFRLQDYID RIIVAIMETN PSILEVK
Length:677
Mass (Da):75,916
Last modified:June 11, 2014 - v1
Checksum:i6B831F139C1D32F3
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O75154RFIP3_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3 ARFO1, KIAA0665
756Annotation score:
A0A0J9YWV4A0A0J9YWV4_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
677Annotation score:
H0Y7F9H0Y7F9_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
136Annotation score:
A0A0J9YXZ3A0A0J9YXZ3_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
136Annotation score:
F6X994F6X994_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
182Annotation score:
A0A0A0MSV1A0A0A0MSV1_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
157Annotation score:
A0A0J9YY48A0A0J9YY48_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
182Annotation score:
A0A0J9YWM0A0A0J9YWM0_HUMAN
Rab11 family-interacting protein 3
RAB11FIP3
157Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023881 Genomic DNA No translation available.
AL049542 Genomic DNA No translation available.
Z98882 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000434585; ENSP00000399644; ENSG00000090565
UCSCiuc059okn.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023881 Genomic DNA No translation available.
AL049542 Genomic DNA No translation available.
Z98882 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliX6RFI8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiX6RFI8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000434585; ENSP00000399644; ENSG00000090565
UCSCiuc059okn.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000090565.15
HGNCiHGNC:17224 RAB11FIP3
OpenTargetsiENSG00000090565
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00440000033742

Miscellaneous databases

ChiTaRSiRAB11FIP3 human

Gene expression databases

BgeeiENSG00000090565 Expressed in 207 organ(s), highest expression level in cortex of kidney
ExpressionAtlasiX6RFI8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR037245 FIP-RBD_C_sf
IPR019018 Rab-bd_FIP-RBD
IPR032920 Rab11-FIP3
PANTHERiPTHR15726:SF6 PTHR15726:SF6, 1 hit
PfamiView protein in Pfam
PF09457 RBD-FIP, 1 hit
SUPFAMiSSF144270 SSF144270, 1 hit
SSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 2 hits
PS51511 FIP_RBD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiX6RFI8_HUMAN
AccessioniPrimary (citable) accession number: X6RFI8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: November 7, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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