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Protein
Submitted name:

Four and a half LIM domains protein 5

Gene

FHL5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Four and a half LIM domains protein 5Imported
Gene namesi
Name:FHL5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000112214.10
HGNCiHGNC:17371 FHL5

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000112214

PTM / Processingi

Proteomic databases

PeptideAtlasiX6RED3

Expressioni

Gene expression databases

BgeeiENSG00000112214 Expressed in 164 organ(s), highest expression level in popliteal artery
ExpressionAtlasiX6RED3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliX6RED3
SMRiX6RED3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 100LIM zinc-bindingInterPro annotationAdd BLAST62
Domaini101 – 160LIM zinc-bindingInterPro annotationAdd BLAST60
Domaini161 – 210LIM zinc-bindingInterPro annotationAdd BLAST50

Keywords - Domaini

LIM domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1704 Eukaryota
ENOG410XP0W LUCA
GeneTreeiENSGT00760000118910

Family and domain databases

InterProiView protein in InterPro
IPR037987 FHL2/3/5
IPR001781 Znf_LIM
PANTHERiPTHR24205 PTHR24205, 1 hit
PfamiView protein in Pfam
PF00412 LIM, 3 hits
SMARTiView protein in SMART
SM00132 LIM, 3 hits
PROSITEiView protein in PROSITE
PS00478 LIM_DOMAIN_1, 3 hits
PS50023 LIM_DOMAIN_2, 3 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

X6RED3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTAHFYCQY CTASLLGKKY VLKDDSPYCV TCYDRVFSNY CEECKKPIES
60 70 80 90 100
DSKDLCYKDR HWHEGCFKCT KCNHSLVEKP FAAKDERLLC TECYSNECSS
110 120 130 140 150
KCFHCKRTIM PGSRKMEFKG NYWHETCFVC ENCRQPIGTK PLISKESGNY
160 170 180 190 200
CVPCFEKEFA HYCNFCKKVI TSGGITFCDQ LWHKECFLCS GCRKDLCEEQ
210
FMSRDDYPFC
Length:210
Mass (Da):24,628
Last modified:June 11, 2014 - v1
Checksum:i7DA9D534F3C6757A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5TD97FHL5_HUMAN
Four and a half LIM domains protein...
FHL5 ACT
284Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei210Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132776 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000450218; ENSP00000396390; ENSG00000112214
UCSCiuc063qdy.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132776 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliX6RED3
SMRiX6RED3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiX6RED3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000450218; ENSP00000396390; ENSG00000112214
UCSCiuc063qdy.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000112214.10
HGNCiHGNC:17371 FHL5
OpenTargetsiENSG00000112214
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1704 Eukaryota
ENOG410XP0W LUCA
GeneTreeiENSGT00760000118910

Gene expression databases

BgeeiENSG00000112214 Expressed in 164 organ(s), highest expression level in popliteal artery
ExpressionAtlasiX6RED3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR037987 FHL2/3/5
IPR001781 Znf_LIM
PANTHERiPTHR24205 PTHR24205, 1 hit
PfamiView protein in Pfam
PF00412 LIM, 3 hits
SMARTiView protein in SMART
SM00132 LIM, 3 hits
PROSITEiView protein in PROSITE
PS00478 LIM_DOMAIN_1, 3 hits
PS50023 LIM_DOMAIN_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiX6RED3_HUMAN
AccessioniPrimary (citable) accession number: X6RED3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: September 12, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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