Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 54 (17 Jun 2020)
Sequence version 1 (11 Jun 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

ATP-dependent Clp proteinase

Gene

tfoG

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperoneSAAS annotation, Hydrolase, ProteaseImported
LigandATP-bindingSAAS annotationImported, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ATP-dependent Clp proteinaseImported
Submitted name:
ATP-dependent Clp proteinase ATP-binding chainImported
Submitted name:
ClpB chaperoneImported
Submitted name:
ClpV1 family T6SS ATPaseImported
Submitted name:
Putative ATP-dependent Clp proteaseImported
Submitted name:
Type VI secretion system ATPase TssHImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:tfoGImported
Synonyms:clpB_3Imported, clpVImported, clpV1_1Imported, clpV1_4Imported, deoGImported, saoGImported, tssHImported, xmoGImported
ORF Names:AWE53_025570Imported, AWG78_018100Imported, B6V57_15255Imported, BON91_20460Imported, C4K41_05065Imported, CT146_00890Imported, DU333_12300Imported, EA189_08670Imported, EA222_08435Imported, EA231_00040Imported, EA250_17630Imported, EA410_00980Imported, EA429_04930Imported, EA434_00980Imported, EPS94_14335Imported, EYX99_17495Imported, FQU83_06865Imported, GQE58_07970Imported, HmCmsJML146_01858Imported, MS8345_03008Imported, NCTC9001_06250Imported, NCTC9434_00959Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000433794 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000306171 Componenti: Unassembled WGS sequence
  • UP000233584 Componenti: Chromosome
  • UP000315141 Componenti: Chromosome
  • UP000353002 Componenti: Unassembled WGS sequence
  • UP000254730 Componenti: Unassembled WGS sequence
  • UP000408257 Componenti: Unassembled WGS sequence
  • UP000065249 Componenti: Unassembled WGS sequence
  • UP000421033 Componenti: Unassembled WGS sequence
  • UP000372890 Componenti: Unassembled WGS sequence
  • UP000238807 Componenti: Unassembled WGS sequence
  • UP000272659 Componenti: Unassembled WGS sequence
  • UP000429662 Componenti: Unassembled WGS sequence
  • UP000297637 Componenti: Unassembled WGS sequence
  • UP000430570 Componenti: Unassembled WGS sequence
  • UP000408798 Componenti: Unassembled WGS sequence
  • UP000324147 Componenti: Chromosome
  • UP000076551 Componenti: Unassembled WGS sequence
  • UP000229602 Componenti: Unassembled WGS sequence
  • UP000290055 Componenti: Unassembled WGS sequence
  • UP000304638 Componenti: Unassembled WGS sequence
  • UP000434743 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini235 – 380AAAInterPro annotationAdd BLAST146
Domaini609 – 780AAAInterPro annotationAdd BLAST172
Domaini780 – 873ClpB_D2-smallInterPro annotationAdd BLAST94

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili449 – 469Sequence analysisAdd BLAST21
Coiled coili481 – 518Sequence analysisAdd BLAST38

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ClpA/ClpB family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105C2Z Bacteria
COG0542 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1780.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR017729 ATPase_T6SS_ClpV1
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR041546 ClpA/ClpB_AAA_lid
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF17871 AAA_lid_9, 1 hit
PF02861 Clp_N, 1 hit
PF10431 ClpB_D2-small, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00300 CLPPROTEASEA

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03345 VI_ClpV1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00870 CLPAB_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

X5FED1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTGNHPAALL RRLNPYCARA LDAAASLCQT RAHAEITIEH WLLKLLEQGE
60 70 80 90 100
GDITVIARRY EWDIDTLWQS LLAHLDTLPR SVRERPQLSE PLTALIRQAW
110 120 130 140 150
LIASLEGDDP QIRSQHLLMA LTEKSMLPAC NDLWVLLSLS RVQLERLRPL
160 170 180 190 200
LDAQSDECPA RQPQVTEPLT SALPETATAD APAKTLTEKQ DDALLAVLNR
210 220 230 240 250
FTEDVTEKAR SGRIDPVFGR DTEIRQMVDI LSRRRKNNPI LVGEPGVGKT
260 270 280 290 300
ALVEGLALRI TEGNVPDSLK TVHIRTLDLG LLQAGAGVKG EFEQRLKNVI
310 320 330 340 350
DAVQKSPEPV LLFIDEAHTI IGAGNQAGGA DAANLLKPAL ARGELRTIAA
360 370 380 390 400
TTWSEYKQYF ERDAALERRF QMVKVDEPDD DTACLMLRGL KARYAQHHGV
410 420 430 440 450
HMLDSAIQTA VRLSRRYLTG RQLPDKAVDL LDTAGARVRM SLDTLPEPLT
460 470 480 490 500
QLHARLAALD IEREAIEQDS VFYPEASPER LAELTDLRDE LQAEAGHLEA
510 520 530 540 550
QYQQEKALAQ QIMTLRQEGT DSTELQQQLR THQGFAPLLA LDVDARAVAT
560 570 580 590 600
VVADWTGIPL SSLLRDEQSD LLSMEQSLEN RVVGQRPALC AIAQRLRAAK
610 620 630 640 650
TGLTPENGPQ GVFLLTGPSG TGKTETALTL ADTLFGGEKS LITINLSEYQ
660 670 680 690 700
EPHTVSQLKG SPPGYVGYGQ GGVLTEAVRK RPYSVVLLDE VEKAHRDVMN
710 720 730 740 750
LFYQVFDRGF MRDGEGREID FRNTVILMTA NLGSDHIMQL LEEKPDATDA
760 770 780 790 800
DLHELLYPLL RDHFQPALMA RFQTVIYRPL GQEAMRTIVE MKLAQVVRRL
810 820 830 840 850
HQHYGLETEI NDSLYDQLTA ACLLPDTGAR NIDSLLNQQI LPVLSQQLLA
860 870 880
QQAAHRKPAQ LRLGWDEEDG IVLEFATEEM Q
Length:881
Mass (Da):98,024
Last modified:June 11, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC50F01831BA35B00
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KF678349 Genomic DNA Translation: AHW84485.1
KF678351 Genomic DNA Translation: AHW84530.1
KF678357 Genomic DNA Translation: AHW84656.1
KF678359 Genomic DNA Translation: AHW84696.1
CP025401 Genomic DNA Translation: AUG94583.1
CP020545 Genomic DNA Translation: AWG07761.1
BFRA01000059 Genomic DNA Translation: GDA06564.1
REBC01000001 Genomic DNA Translation: KAA1834341.1
REBD01000015 Genomic DNA Translation: KAA1836610.1
RDTU01000004 Genomic DNA Translation: KAA1885943.1
RDVE01000002 Genomic DNA Translation: KAA2093654.1
RDVD01000001 Genomic DNA Translation: KAA2099764.1
REBJ01000001 Genomic DNA Translation: KAA2165602.1
RDVY01000003 Genomic DNA Translation: KAA2190329.1
WSWB01000004 Genomic DNA Translation: MWD98109.1
PENJ01000001 Genomic DNA Translation: PIM25206.1
PSNQ01000003 Genomic DNA Translation: PPE32033.1
CP042246 Genomic DNA Translation: QDX35490.1
RRUU01000005 Genomic DNA Translation: RRK94230.1
LVSP02000001 Genomic DNA Translation: RRO51334.1
LQSL02000003 Genomic DNA Translation: RRO78080.1
SCIX01000010 Genomic DNA Translation: RXB45687.1
UGFV01000001 Genomic DNA Translation: STN16296.1
MTXY01000042 Genomic DNA Translation: TFA37032.1
SSQV01000063 Genomic DNA Translation: TIJ88405.1
CAADIS010000005 Genomic DNA Translation: VFS40093.1

NCBI Reference Sequences

More...
RefSeqi
WP_000147358.1, NZ_WJRI01000006.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ALD23877; ALD23877; AN206_05305
CRL91065; CRL91065; AL505_50179

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.7203.peg.5089

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF678349 Genomic DNA Translation: AHW84485.1
KF678351 Genomic DNA Translation: AHW84530.1
KF678357 Genomic DNA Translation: AHW84656.1
KF678359 Genomic DNA Translation: AHW84696.1
CP025401 Genomic DNA Translation: AUG94583.1
CP020545 Genomic DNA Translation: AWG07761.1
BFRA01000059 Genomic DNA Translation: GDA06564.1
REBC01000001 Genomic DNA Translation: KAA1834341.1
REBD01000015 Genomic DNA Translation: KAA1836610.1
RDTU01000004 Genomic DNA Translation: KAA1885943.1
RDVE01000002 Genomic DNA Translation: KAA2093654.1
RDVD01000001 Genomic DNA Translation: KAA2099764.1
REBJ01000001 Genomic DNA Translation: KAA2165602.1
RDVY01000003 Genomic DNA Translation: KAA2190329.1
WSWB01000004 Genomic DNA Translation: MWD98109.1
PENJ01000001 Genomic DNA Translation: PIM25206.1
PSNQ01000003 Genomic DNA Translation: PPE32033.1
CP042246 Genomic DNA Translation: QDX35490.1
RRUU01000005 Genomic DNA Translation: RRK94230.1
LVSP02000001 Genomic DNA Translation: RRO51334.1
LQSL02000003 Genomic DNA Translation: RRO78080.1
SCIX01000010 Genomic DNA Translation: RXB45687.1
UGFV01000001 Genomic DNA Translation: STN16296.1
MTXY01000042 Genomic DNA Translation: TFA37032.1
SSQV01000063 Genomic DNA Translation: TIJ88405.1
CAADIS010000005 Genomic DNA Translation: VFS40093.1
RefSeqiWP_000147358.1, NZ_WJRI01000006.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiALD23877; ALD23877; AN206_05305
CRL91065; CRL91065; AL505_50179
PATRICifig|562.7203.peg.5089

Phylogenomic databases

eggNOGiENOG4105C2Z Bacteria
COG0542 LUCA

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR017729 ATPase_T6SS_ClpV1
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR041546 ClpA/ClpB_AAA_lid
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF17871 AAA_lid_9, 1 hit
PF02861 Clp_N, 1 hit
PF10431 ClpB_D2-small, 1 hit
PRINTSiPR00300 CLPPROTEASEA
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit
TIGRFAMsiTIGR03345 VI_ClpV1, 1 hit
PROSITEiView protein in PROSITE
PS00870 CLPAB_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiX5FED1_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: X5FED1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: June 17, 2020
This is version 54 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again