Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cadherin 10 type 2 isoform B

Gene

CDH10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cadherins are calcium-dependent cell adhesion proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionUniRule annotation
LigandCalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin 10 type 2 isoform BImported
Gene namesi
Name:CDH10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei603 – 632HelicalSequence analysisAdd BLAST30

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500495490223 – 786Sequence analysisAdd BLAST764

Structurei

3D structure databases

ProteinModelPortaliX5DNG6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 158CAInterPro annotationAdd BLAST82
Domaini182 – 267CAInterPro annotationAdd BLAST86
Domaini291 – 383CAInterPro annotationAdd BLAST93
Domaini406 – 487CAInterPro annotationAdd BLAST82
Domaini510 – 594CAInterPro annotationAdd BLAST85

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 2 hits

Sequencei

Sequence statusi: Fragment.

X5DNG6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIHQFLLLF LFWVCLPHFC SPEIMFRRTP VPQQRILSSR VPRSDGKILH
60 70 80 90 100
RQKRGWMWNQ FFLLEEYTGS DYQYVGKLHS DQDKGDGSLK YILSGDGAGT
110 120 130 140 150
LFIIDEKTGD IHATRRIDRE EKAFYTLRAQ AINRRTLRPV EPESEFVIKI
160 170 180 190 200
HDINDNEPTF PEEIYTASVP EMSVVGTSVV QVTATDADDP SYGNSARVIY
210 220 230 240 250
SILQGQPYFS VEPETGIIRT ALPNMNRENR EQYQVVIQAK DMGGQMGGLS
260 270 280 290 300
GTTTVNITLT DVNDNPPRFP QNTIHLRVLE SSPVGTAIGS VKATDADTGK
310 320 330 340 350
NAEVEYRIID GDGTDMFDIV TEKDTQEGII TVKKPLDYES RRLYTLKVEA
360 370 380 390 400
ENTHVDPRFY YLGPFKDTTI VKISIEDVDE PPVFSRSSYL FEVHEDIEVG
410 420 430 440 450
TIIGTVMARD PDSISSPIRF SLDRHTDLDR IFNIHSGNGS LYTSKPLDRE
460 470 480 490 500
LSQWHNLTVI AAEINNPKET TRVAVFVRIL DVNDNAPQFA VFYDTFVCEN
510 520 530 540 550
ARPGQLIQTI SAVDKDDPLG GQKFFFSLAA VNPNFTVQDN EDNTARILTR
560 570 580 590 600
KNGFNRHEIS TYLLPVVISD NDYPIQSSTG TLTIRVCACD SQGNMQSCSA
610 620 630 640 650
EALLLPAGLS TGALIAILLC IIILLVVLFA ALKRQRKKEP LILSKEDIRD
660 670 680 690 700
NIVSYNDEGG GEEDTQAFDI GTLRNPAAIE EKKLRRDIIP ETLFIPRRTP
710 720 730 740 750
TAPDNTDVRD FINERLKEHD LDPTAPPYDS LATYAYEGND SIAESLSSLE
760 770 780
SGTTEGDQNY DYLREWGPRF NKLAEMYGGG ESDKDS
Length:786
Mass (Da):88,239
Last modified:June 11, 2014 - v1
Checksum:i3BE3B1BD6B060377
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei786Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534806 mRNA Translation: AHW56446.1
RefSeqiNP_001304153.1, NM_001317224.1
XP_016864404.1, XM_017008915.1
UniGeneiHs.92489

Genome annotation databases

GeneIDi1008

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534806 mRNA Translation: AHW56446.1
RefSeqiNP_001304153.1, NM_001317224.1
XP_016864404.1, XM_017008915.1
UniGeneiHs.92489

3D structure databases

ProteinModelPortaliX5DNG6
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1008

Organism-specific databases

CTDi1008

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA

Miscellaneous databases

ChiTaRSiCDH10 human
GenomeRNAii1008

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiX5DNG6_HUMAN
AccessioniPrimary (citable) accession number: X5DNG6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: January 31, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again