Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 51 (16 Oct 2019)
Sequence version 1 (11 Jun 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Rapamycin-insensitive companion of Tor, isoform C

Gene

rictor

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Rapamycin-insensitive companion of Tor, isoform CImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rictorImported
Synonyms:8002Imported, Dmel\CG8002Imported, dRicImported, dRICTORImported, dRictorImported, RictorImported
ORF Names:CG8002Imported, Dmel_CG8002Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0031006 rictor

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
X2JFR5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0031006 Expressed in 28 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
X2JFR5 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini48 – 428RICTOR_NInterPro annotationAdd BLAST381
Domaini568 – 788RICTOR_MInterPro annotationAdd BLAST221
Domaini964 – 1038RICTOR_VInterPro annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1424 – 1455DisorderedSequence analysisAdd BLAST32
Regioni1683 – 1741DisorderedSequence analysisAdd BLAST59
Regioni1772 – 1794DisorderedSequence analysisAdd BLAST23

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1683 – 1703PolarSequence analysisAdd BLAST21

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3694 Eukaryota
ENOG410XQ5Z LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000002096

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR028268 Pianissimo_fam
IPR028267 Pianissimo_N
IPR029453 Rictor_IV
IPR029451 RICTOR_M
IPR029452 RICTOR_V

The PANTHER Classification System

More...
PANTHERi
PTHR13298 PTHR13298, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14663 RasGEF_N_2, 1 hit
PF14666 RICTOR_M, 1 hit
PF14664 RICTOR_N, 1 hit
PF14668 RICTOR_V, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01307 RICTOR_M, 1 hit
SM01308 RICTOR_N, 1 hit
SM01310 RICTOR_V, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

X2JFR5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWPYYSFIKV SQDPEDFYRL DPQRSAAENA FEIYSMLCLE ETRDTKRLFL
60 70 80 90 100
LNALASLCLG ARKGSHHSNI RFTTEELLYC LSASLVHTFT QVRAAALRTI
110 120 130 140 150
RYAISTPNDI KTFNALQLQH LLCRSIDLML KNDDERVQAL KLVRKMLAIA
160 170 180 190 200
PEDISPAVVR CLVSLADSGI EENDNLLRAC LATLAEFAVL NPALLIVCGG
210 220 230 240 250
VTSITRNVLE CHNPRIAESL CGVLLYLLEW PQTRNICGVR LDCLAAPYCD
260 270 280 290 300
FTYRQSIVDK NKDARELRYT SCRLALLSVL RSWTGTLEFC DPSKPSGLKA
310 320 330 340 350
IVDALYLNQI EVRKAILDLL YELLTLPQPT WTDDYAVALQ AVDPSDFQDT
360 370 380 390 400
WLLSNGFVSA EGRSILPTLA ARAPSVVEQH LALMLYCFLE TGLLNALVEV
410 420 430 440 450
VVSSDQFVSV QATVLIGKIL QLMHTHLPPD ICCTSPALPT LVSHATLGNQ
460 470 480 490 500
QANAAVAALQ NYQKLLRQRP ASRSLFLDSI IQGGALIQTR LFRRHLNVQE
510 520 530 540 550
QAGPVLQLQE TAEAAAFAVP PVTQFRGTLD RSRLDSVSSS DESNSQASTS
560 570 580 590 600
SRSSFRLKRK FLPQALYDNF RAFNRLLTDS RVLSQADAHL WDWDVITTIL
610 620 630 640 650
KSNLIRKLDY TQGKFLKRLV DFYKPRNNRF SHQDLVPGQR LPTYVSAGLD
660 670 680 690 700
LIDVLLSSNE LECMRFITDY FSDISQQLAA VTTSNRAHDC LFSPQHMNNT
710 720 730 740 750
MCQQYFLYIG RMCRTVKGIE VLKNTTVFEY LINLVRVTDH VCYVKLIVSG
760 770 780 790 800
LNYSYEKLPR QVLEKALTSA KTRGRLYSTQ FMAVLLRARL PHFEVWGIPL
810 820 830 840 850
IINQTRDSDR SVGLAAMDVL EEACHDKYYL EEIVSRWPNL THRGDAGRLL
860 870 880 890 900
MARYYSLPRG LNSTMARIED EIRYWRNGYN KRYVLLVEAD THSSLTLHIR
910 920 930 940 950
NEDGYYSRRN CNQRPQTVPP NVAPHLYGQM AQTGQGMTAL RKHGDLPQLL
960 970 980 990 1000
ELLRRAKCTD DAECLELKAA IWALAHASTH SNGIEYFVEL NARLYEKLIV
1010 1020 1030 1040 1050
LVTKCEVYSV RATCFSALGL IAGTQAGANI LFKLNWLSVR HDKNTMWPVH
1060 1070 1080 1090 1100
QPEDWMSSQY TPVRHYYEDV PADNMTMMDD YIERFYETGS DFWHMLADQT
1110 1120 1130 1140 1150
DASGGGGGVA GTVVGMHPIV QDPNATITTT DSVRTTTDDV HPRMLVGVAA
1160 1170 1180 1190 1200
KSKTLPEGSN LRQGKHQRSL SESKTTDVIS LLGSGVGTMS GAVLYPTPYQ
1210 1220 1230 1240 1250
HRIRYNSCTD SNTSGVSSCE SVTGRTAAAY AAAANELQQF PLSPIPSMSN
1260 1270 1280 1290 1300
LLESDELFRR NQLATSMLPS TLSPMAMKGY VQLRSLRKHS RPVFSESSAE
1310 1320 1330 1340 1350
FYDFAEILDT PEVQMRKLDW THSHRRLKVR SLDRQLSDVY RRLSADELNV
1360 1370 1380 1390 1400
LLPTLNAPKF LPPNDLKGPC YAGICLPKNV LDLFPTRNLS RTYVSRDIQD
1410 1420 1430 1440 1450
QDIVGINLLN TMLRPQCLND SLTNEGGDES SVISSLSDVS SASRRQTRQL
1460 1470 1480 1490 1500
QQGAKHSRSL CLHCARSPRQ QRNDSGSHSN GGGGASLAPC ELYSSAAAAL
1510 1520 1530 1540 1550
VAAGIQAGPV LAKKSGSSAQ GASAALGADI SFHSPESMLS EDSLPDRLTA
1560 1570 1580 1590 1600
SILYNVQRLA NPVSAKQSKM ALLELKQKHP HAFQDICLYS EACKTIGRSS
1610 1620 1630 1640 1650
YRMIARRFLQ ELFLDLNFDS FYVEPQLIIG ARKFSAEEKA EATAPTAMQA
1660 1670 1680 1690 1700
MPFKQTILKP KPAAQLASVY ETSWENLLMD QSPRINKSSP ADQPANAQTK
1710 1720 1730 1740 1750
AKARNQLHID DTESSLSSTD GENDSGEDVC DGSGAGTQAS SVTTAHTALP
1760 1770 1780 1790 1800
TGNSNRSSIG TCTASQLVPG AATSNSAGAG TSASDNASTS LKNENRQFTR
1810 1820 1830 1840 1850
GRFYTLELDL SCTKNKFPIK NRSQRTPTPP PIESLIESKP TVQTDVNTSA
1860 1870 1880 1890 1900
LPIMQRTGGS NDSSSALRYS TVTKSLSASM ARPVGSLYCE KRLQSSKSEA
1910 1920
VLDEVAKARR ASGGVGLTTV RDNS
Length:1,924
Mass (Da):213,192
Last modified:June 11, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE60A94F4E8FD2582
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VWJ6Q9VWJ6_DROME
FI03615p
rictor 8002, Dmel\CG8002, dRic, dRICTOR, dRictor
1,936Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X2JL73X2JL73_DROME
Rapamycin-insensitive companion of ...
rictor 8002, Dmel\CG8002, dRic, dRICTOR, dRictor
1,916Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AHN59903.1

NCBI Reference Sequences

More...
RefSeqi
NP_001285433.1, NM_001298504.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0343635; FBpp0310228; FBgn0031006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32919

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AHN59903.1
RefSeqiNP_001285433.1, NM_001298504.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiX2JFR5

Genome annotation databases

EnsemblMetazoaiFBtr0343635; FBpp0310228; FBgn0031006
GeneIDi32919

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
253260
FlyBaseiFBgn0031006 rictor

Phylogenomic databases

eggNOGiKOG3694 Eukaryota
ENOG410XQ5Z LUCA
GeneTreeiENSGT00390000002096

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32919

Gene expression databases

BgeeiFBgn0031006 Expressed in 28 organ(s), highest expression level in female gonad
ExpressionAtlasiX2JFR5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR028268 Pianissimo_fam
IPR028267 Pianissimo_N
IPR029453 Rictor_IV
IPR029451 RICTOR_M
IPR029452 RICTOR_V
PANTHERiPTHR13298 PTHR13298, 1 hit
PfamiView protein in Pfam
PF14663 RasGEF_N_2, 1 hit
PF14666 RICTOR_M, 1 hit
PF14664 RICTOR_N, 1 hit
PF14668 RICTOR_V, 1 hit
SMARTiView protein in SMART
SM01307 RICTOR_M, 1 hit
SM01308 RICTOR_N, 1 hit
SM01310 RICTOR_V, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiX2JFR5_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: X2JFR5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: October 16, 2019
This is version 51 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again