Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 53 (26 Feb 2020)
Sequence version 1 (11 Jun 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Sodium channel protein

Gene

para

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channelUniRule annotation, Voltage-gated channelUniRule annotation
Biological processIon transport, Sodium transport, Transport
LigandSodium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:paraImported
Synonyms:basImported, bssImported, Dmel\CG9907Imported, DmNa[[V]]Imported, DmNa[[v]]Imported, DmNa[[v]]1Imported, DmNavImported, DmNav1Imported, l(1)14DaImported, l(1)ESHS48Imported, lincRNA.S9469Imported, Nav1Imported, OcdImported, olfDImported, parImported, ParaImported, sblImported, sbl-1Imported, ShuImported, ShuddererImported
ORF Names:CG9907Imported, Dmel_CG9907Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0285944 para

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei133 – 160HelicalUniRule annotationAdd BLAST28
Transmembranei204 – 226HelicalUniRule annotationAdd BLAST23
Transmembranei238 – 256HelicalUniRule annotationAdd BLAST19
Transmembranei262 – 284HelicalUniRule annotationAdd BLAST23
Transmembranei394 – 416HelicalUniRule annotationAdd BLAST23
Transmembranei799 – 822HelicalUniRule annotationAdd BLAST24
Transmembranei843 – 860HelicalUniRule annotationAdd BLAST18
Transmembranei872 – 896HelicalUniRule annotationAdd BLAST25
Transmembranei931 – 950HelicalUniRule annotationAdd BLAST20
Transmembranei971 – 990HelicalUniRule annotationAdd BLAST20
Transmembranei1005 – 1028HelicalUniRule annotationAdd BLAST24
Transmembranei1331 – 1351HelicalUniRule annotationAdd BLAST21
Transmembranei1357 – 1377HelicalUniRule annotationAdd BLAST21
Transmembranei1458 – 1484HelicalUniRule annotationAdd BLAST27
Transmembranei1547 – 1565HelicalUniRule annotationAdd BLAST19
Transmembranei1577 – 1596HelicalUniRule annotationAdd BLAST20
Transmembranei1608 – 1627HelicalUniRule annotationAdd BLAST20
Transmembranei1671 – 1694HelicalUniRule annotationAdd BLAST24
Transmembranei1757 – 1780HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
X2JFE8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0264255 Expressed in head and 8 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
X2JFE8 differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1801 – 1836EF-handInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni35 – 73DisorderedSequence analysisAdd BLAST39
Regioni541 – 560DisorderedSequence analysisAdd BLAST20
Regioni659 – 679DisorderedSequence analysisAdd BLAST21
Regioni1131 – 1205DisorderedSequence analysisAdd BLAST75
Regioni1925 – 2020DisorderedSequence analysisAdd BLAST96

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili420 – 470Sequence analysisAdd BLAST51

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi35 – 51PolyampholyteSequence analysisAdd BLAST17
Compositional biasi541 – 559PolarSequence analysisAdd BLAST19
Compositional biasi1131 – 1145PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1146 – 1160PolarSequence analysisAdd BLAST15
Compositional biasi1161 – 1190PolyampholyteSequence analysisAdd BLAST30
Compositional biasi1191 – 1205AcidicSequence analysisAdd BLAST15
Compositional biasi1925 – 1948PolyampholyteSequence analysisAdd BLAST24

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sodium channel (TC 1.A.1.10) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2301 Eukaryota
ENOG410XNP6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000167131

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002048 EF_hand_dom
IPR005821 Ion_trans_dom
IPR001696 Na_channel_asu
IPR010526 Na_trans_assoc
IPR024583 Na_trans_cytopl
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520 Ion_trans, 4 hits
PF06512 Na_trans_assoc, 1 hit
PF11933 Na_trans_cytopl, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00170 NACHANNEL

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50222 EF_HAND_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 55 potential isoforms that are computationally mapped.Show allAlign All

X2JFE8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEDSDSISE EERSLFRPFT RESLVQIEQR IAAEHEKQKE LERKRAEGEI
60 70 80 90 100
RYDDEDEDEG PQPDPTLEQG VPIPVRLQGS FPPELASTPL EDIDPYYSNV
110 120 130 140 150
LTFVVVSKGK DIFRFSASKA MWMLDPFNPI RRVAIYILVH PLFSLFIITT
160 170 180 190 200
ILVNCILMIM PTTPTVESTE VIFTGIYTFE SAVKVMARGF ILCPFTYLRD
210 220 230 240 250
AWNWLDFVVI ALAYVTMGID LGNLAALRTF RVLRALKTVA IVPGLKTIVG
260 270 280 290 300
AVIESVKNLR DVIILTMFSL SVFALMGLQI YMGVLTQKCI KKFPLDGSWG
310 320 330 340 350
NLTDENWDYH NRNSSNWYSE DEGISFPLCG NISGAGQCDD DYVCLQGFGP
360 370 380 390 400
NPNYGYTSFD SFGWAFLSAF RLMTQDFWED LYQLVLRAAG PWHMLFFIVI
410 420 430 440 450
IFLGSFYLVN LILAIVAMSY DELQKKAEEE EAAEEEAIRE AEEAAAAKAA
460 470 480 490 500
KLEERANAQA QAAADAAAAE EAALHPEMAK SPTYSCISYE LFVGGEKGND
510 520 530 540 550
DNNKEKMSIR SVEVESESVS VIQRQPAPTT AHQATKVRKV STTSLSLPGS
560 570 580 590 600
PFNIRRGSRS SHKYTIRNGR GRFGIPGSDR KPLVLSTYQD AQQHLPYADD
610 620 630 640 650
SNAVTPMSEE NGAIIVPVYY GNLGSRHSSY TSHQSRISYT SHGDLLGGMA
660 670 680 690 700
VMGVSTMTKE SKLRNRNTRN QSVGATNGGT TCLDTNHKLD HRDYEIGLEC
710 720 730 740 750
TDEAGKIKHH DNPFIEPVQT QTVVDMKDVM VLNDIIEQAA GRHSRASDRG
760 770 780 790 800
VSVYYFPTED DDEDGPTFKD KALEVILKGI DVFCVWDCCW VWLKFQEWVS
810 820 830 840 850
LIVFDPFVEL FITLCIVVNT MFMAMDHHDM NKEMERVLKS GNYFFTATFA
860 870 880 890 900
IEATMKLMAM SPKYYFQEGW NIFDFIIVAL SLLELGLEGV QGLSVLRSFR
910 920 930 940 950
LLRVFKLAKS WPTLNLLISI MGRTMGALGN LTFVLCIIIF IFAVMGMQLF
960 970 980 990 1000
GKNYHDHKDR FPDGDLPRWN FTDFMHSFMI VFRVLCGEWI ESMWDCMYVG
1010 1020 1030 1040 1050
DVSCIPFFLA TVVIGNLVVL NLFLALLLSN FGSSSLSAPT ADNDTNKIAE
1060 1070 1080 1090 1100
AFNRIGRFKS WVKRNIADCF KLIRNKLTNQ ISDQPSEHGD NELELGHDEI
1110 1120 1130 1140 1150
LADGLIKKGI KEQTQLEVAI GDGMEFTIHG DMKNNKPKKS KYLNNATDDD
1160 1170 1180 1190 1200
TASINSYGSH KNRPFKDESH KGSAETMEGE EKRDASKEDL GLDEELDEEG
1210 1220 1230 1240 1250
ECEEGPLDGD IIIHAHDEDI LDEYPADCCP DSYYKKFPIL AGDDDSPFWQ
1260 1270 1280 1290 1300
GWGNLRLKTF QLIENKYFET AVITMILMSS LALALEDVHL PQRPILQDIL
1310 1320 1330 1340 1350
YYMDRIFTVI FFLEMLIKWL ALGFKVYFTN AWCWLDFVIV MVVVNALVQA
1360 1370 1380 1390 1400
IPSIFNVLLV CLIFWLIFAI MGVQLFAGKY FKCEDMNGTK LSHEIIPNRN
1410 1420 1430 1440 1450
ACESENYTWV NSAMNFDHVG NAYLCLFQVA TFKGWIQIMN DAIDSREVDK
1460 1470 1480 1490 1500
QPIRETNIYM YLYFVFFIIF GSFFTLNLFI GVIIDNFNEQ KKKAGGSLEM
1510 1520 1530 1540 1550
FMTEDQKKYY NAMKKMGSKK PLKAIPRPRW RPQAIVFEIV TDKKFDIIIM
1560 1570 1580 1590 1600
LFIGLNMFTM TLDRYDASDT YNAVLDYLNA IFVVIFSSEC LLKIFALRYH
1610 1620 1630 1640 1650
YFIEPWNLFD VVVVILSILG LVLSDIIEKY FVSPTLLRVV RVAKVGRVLR
1660 1670 1680 1690 1700
LVKGAKGIRT LLFALAMSLP ALFNICLLLF LVMFIFAIFG MSFFMHVKEK
1710 1720 1730 1740 1750
SGINDVYNFK TFGQSMILLF QMSTSAGWDG VLDAIINEEA CDPPDNDKGY
1760 1770 1780 1790 1800
PGNCGSATVG ITFLLSYLVI SFLIVINMYI AVILENYSQA TEDVQEGLTD
1810 1820 1830 1840 1850
DDYDMYYEIW QQFDPEGTQY IRYDQLSEFL DVLEPPLQIH KPNKYKIISM
1860 1870 1880 1890 1900
DIPICRGDLM YCVDILDALT KDFFARKGNP IEETGEIGEI AARPDTEGYE
1910 1920 1930 1940 1950
PVSSTLWRQR EEYCARLIQH AWRKHKARGE GGGSFEPDTD HGDGGDPDAG
1960 1970 1980 1990 2000
DPAPDEATDG DAPAGGDGSV NGTAEGAADA DESNVNSPGE DAAAAAAAAA
2010 2020 2030 2040 2050
AAAAAGTTTA GSPGAGSAGR QTAVLVESDG FVTKNGHKVV IHSRSPSITS

RTADV
Length:2,055
Mass (Da):230,840
Last modified:June 11, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEB3D2210233DCB46
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 55 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P35500SCNA_DROME
Sodium channel protein para
para CG9907
2,131Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X2JKQ0X2JKQ0_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,131Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7Z0Z2B7Z0Z2_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,114Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MS71M9MS71_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,092Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MS73M9MS73_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,079Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MS92M9MS92_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,143Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MSP9M9MSP9_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,062Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MS61M9MS61_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,108Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MS65M9MS65_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,100Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M9MS66M9MS66_DROME
Sodium channel protein
para bas, bss, Dmel\CG9907, DmNa[[V]], DmNa[[v]]
2,097Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AHN59803.1

NCBI Reference Sequences

More...
RefSeqi
NP_001285333.1, NM_001298404.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0344944; FBpp0311217; FBgn0285944

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32619

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AHN59803.1
RefSeqiNP_001285333.1, NM_001298404.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiX2JFE8

Genome annotation databases

EnsemblMetazoaiFBtr0344944; FBpp0311217; FBgn0285944
GeneIDi32619

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
32619
FlyBaseiFBgn0285944 para

Phylogenomic databases

eggNOGiKOG2301 Eukaryota
ENOG410XNP6 LUCA
GeneTreeiENSGT00940000167131

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
para fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32619

Gene expression databases

BgeeiFBgn0264255 Expressed in head and 8 other tissues
ExpressionAtlasiX2JFE8 differential

Family and domain databases

Gene3Di1.20.120.350, 3 hits
InterProiView protein in InterPro
IPR002048 EF_hand_dom
IPR005821 Ion_trans_dom
IPR001696 Na_channel_asu
IPR010526 Na_trans_assoc
IPR024583 Na_trans_cytopl
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF00520 Ion_trans, 4 hits
PF06512 Na_trans_assoc, 1 hit
PF11933 Na_trans_cytopl, 1 hit
PRINTSiPR00170 NACHANNEL
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiX2JFE8_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: X2JFE8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: February 26, 2020
This is version 53 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again