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Entry version 56 (10 Feb 2021)
Sequence version 1 (11 Jun 2014)
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Protein
Submitted name:

Wispy, isoform B

Gene

wisp

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferaseImported, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Wispy, isoform BImported (EC:2.7.7.19Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:wispImported
Synonyms:DmCG15737Imported, Dmel\CG15737Imported, fs(1)M19Imported, PAPImported, TAMPImported, TUTase2Imported, WispImported, WispyImported
ORF Names:CG15737Imported, Dmel_CG15737Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0260780, wisp

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0260780, Expressed in egg cell and 25 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
X2JEK3, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
X2JEK3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1210 – 1271PAP-associatedInterPro annotationAdd BLAST62

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni75 – 155DisorderedSequence analysisAdd BLAST81
Regioni175 – 338DisorderedSequence analysisAdd BLAST164
Regioni424 – 542DisorderedSequence analysisAdd BLAST119
Regioni733 – 769DisorderedSequence analysisAdd BLAST37
Regioni801 – 865DisorderedSequence analysisAdd BLAST65
Regioni879 – 927DisorderedSequence analysisAdd BLAST49
Regioni1319 – 1358DisorderedSequence analysisAdd BLAST40

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi424 – 488PolarSequence analysisAdd BLAST65
Compositional biasi525 – 542PolarSequence analysisAdd BLAST18
Compositional biasi733 – 748PolarSequence analysisAdd BLAST16
Compositional biasi749 – 763Pro-richSequence analysisAdd BLAST15
Compositional biasi801 – 816PolarSequence analysisAdd BLAST16
Compositional biasi824 – 865PolarSequence analysisAdd BLAST42
Compositional biasi907 – 922Pro-richSequence analysisAdd BLAST16
Compositional biasi1319 – 1336PolarSequence analysisAdd BLAST18

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156640

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_258864_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
RLWRYLF

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.460.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043519, NT_sf
IPR002058, PAP_assoc

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03828, PAP_assoc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81301, SSF81301, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

X2JEK3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFSTRISGDM KIFAADVAES SVTATCNTSV QQQQSQQLEF RTRMSAGSPS
60 70 80 90 100
SKSGQCHLKF GKYNNKTANL LRQVNSCHSS NSSSNTSNNN NEAIKGQQQQ
110 120 130 140 150
PLHYCNSNNS HSWARKKYFG NGNSNNSLLQ QQQQPSSFFQ RQQQQHQMQM
160 170 180 190 200
QQEKQATNNN DALMKNQNVV NAHVSDCKSS DSNNNSTSSS NNNSTISSNN
210 220 230 240 250
NNTSSASNNN TGSSSSCSNR TKPAKWLNEN SSSSSSSNNN NISCRNNNTS
260 270 280 290 300
SIDTKRRNSS AGATAAYYRK SESESGSSEG AAESTETEAT RTGGCNSNRT
310 320 330 340 350
AESSSADGGT QATMGKSQDQ EQDQTVKQRP RQQPLSFWKT NYPQTSATQL
360 370 380 390 400
KDETVAAVVS AAAVAAAAAA ASASEQQQQQ QSLSIEHRRN SGYQQHQQHN
410 420 430 440 450
YYPYYYSQPK QLTIASFLQK EMLPDSTEKS SSNTGGSNMI RSSSNGNSNF
460 470 480 490 500
SRHQYGHQST GSGYQQQQQR YRNAQNVYQQ YQHQQQHHAQ QHTHPHFRRK
510 520 530 540 550
HSDNGSGINK KMHYSPPGKS GDPADRSASG QQQHHHPHQQ QKTIEILASS
560 570 580 590 600
HFNAMHRRMQ GGNNKNGYYQ HSYNPMTGEV GSTPTRSEHQ NIYNLTYIHV
610 620 630 640 650
DTEATGEAAS AAGSTPVVKP SLLSKPNISI TPASSTTPTT VDRALLPAVR
660 670 680 690 700
SVSAPASGSA LPAPANHVRN MFPPPPLAML GGHGLLSPVT TTTPTKMISC
710 720 730 740 750
AQLDEAITAA AASGDKLSTS PSYNQAGHYI MPPQQQQQQQ LSSHPIPTGT
760 770 780 790 800
SSHPPPPPPP HMFFHFADGF CNPGQGHQAP PATMWPHSSS PCYPASYGSS
810 820 830 840 850
CGSGTGAGTS PHNNDGNAGA LRPASPALSS SSLGSESQWS GTSNRSRLGH
860 870 880 890 900
NGHPSISPTP SALGSAQLSP HLAEMRVQHP LHQQHPPSHA SHRPHGQMGG
910 920 930 940 950
HAMSSYVPHR PPPPPHPSIS SPNPTPVATG AGGPWYEMIL PPDRYLAQAR
960 970 980 990 1000
NIEVTVQPEK LICMCKYDNL SAEIWKRFRG AQQTHNKFKL KMRLWRYLYL
1010 1020 1030 1040 1050
WMHQPMFERY RICLVGSTIT GFGTDSSDID MCLLPEQGVH PHQHQYHQHH
1060 1070 1080 1090 1100
HFHNEKRTEA LIILTLFNAV LKDTEVFQDF NLIEARVPIL RFKDISNGIE
1110 1120 1130 1140 1150
VDLNFNNCVG IKNTYLLQLY AQMDWRTRPL VVIVKLWAQY HDINDAKRMT
1160 1170 1180 1190 1200
ISSYSLVLMV LHYLQHACVP HVLPCLHSLY PEKFQLGQQD CLDLDLIEPI
1210 1220 1230 1240 1250
EPYQALNTQT LGEHLLGFFK YYSTFDFRNF AISIRTGGVL PVSTCRMAKS
1260 1270 1280 1290 1300
PKNDVYQWKE LNIEEPFDLS NTARSVYDGP TFERVKAVFL ISARRLDHTL
1310 1320 1330 1340 1350
DLATIFRPIH HVPEHFPQLQ QHQQQFEQQL HHPISGQQRS AGGGGDGANP
1360 1370
VPSTLNPDAA STFAETTAAH VA
Length:1,372
Mass (Da):151,184
Last modified:June 11, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44ABEDC8161E6A76
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VYS4GLD2B_DROME
Poly(A) RNA polymerase gld-2 homolo...
wisp CG15737
1,373Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
L7XBB9L7XBB9_DROME
RE03648p1
wisp DmCG15737, Dmel\CG15737, fs(1)M19, PAP, TAMP
1,373Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AHN59613.1

NCBI Reference Sequences

More...
RefSeqi
NP_001285143.1, NM_001298214.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0342742; FBpp0309610; FBgn0260780

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
32152

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AHN59613.1
RefSeqiNP_001285143.1, NM_001298214.1

3D structure databases

SMRiX2JEK3
ModBaseiSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0342742; FBpp0309610; FBgn0260780
GeneIDi32152

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
32152
FlyBaseiFBgn0260780, wisp

Phylogenomic databases

GeneTreeiENSGT00940000156640
HOGENOMiCLU_258864_0_0_1
OMAiRLWRYLF

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
32152, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
32152

Gene expression databases

BgeeiFBgn0260780, Expressed in egg cell and 25 other tissues
ExpressionAtlasiX2JEK3, baseline and differential

Family and domain databases

Gene3Di3.30.460.10, 1 hit
InterProiView protein in InterPro
IPR043519, NT_sf
IPR002058, PAP_assoc
PfamiView protein in Pfam
PF03828, PAP_assoc, 1 hit
SUPFAMiSSF81301, SSF81301, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiX2JEK3_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: X2JEK3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: February 10, 2021
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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