UniProtKB - X2J9A5 (X2J9A5_DROME)
Protein
Submitted name:
Uncharacterized protein, isoform B
Gene
CG9332
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- glyoxylate reductase (NADP) activity Source: GO_Central
- hydroxypyruvate reductase activity Source: GO_Central
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: GO_Central
- protein homodimerization activity Source: GO_Central
Keywordsi
Molecular function | OxidoreductaseUniRule annotationImported |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CG9332Imported Synonyms:BcDNA:LD14730Imported, CCG31673Imported, Dmel\CG31673Imported ORF Names:CG31673Imported, Dmel_CG31673Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0051673 CG31673 |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Expressioni
Gene expression databases
Bgeei | FBgn0051673 Expressed in 31 organ(s), highest expression level in adult Malpighian tubule (Drosophila) |
ExpressionAtlasi | X2J9A5 baseline and differential |
Structurei
3D structure databases
ProteinModelPortali | X2J9A5 |
SMRi | X2J9A5 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 321 | 2-Hacid_dhInterPro annotationAdd BLAST | 312 | |
Domaini | 116 – 293 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 178 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0069 Eukaryota COG1052 LUCA |
GeneTreei | ENSGT00940000170865 |
OrthoDBi | 1378766at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
X2J9A5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRATRAFKV LISHPNVPAP ALELLRSRGA ETIICQSVPP SRDEILQKVP
60 70 80 90 100
GVDAIYWAHY QPLNAGILDA AGSQLRCVST MSSGIDFVDI PEFQKRGIPL
110 120 130 140 150
GHTPGVVKNA VADLAIGLMI AAGRHFHAGR TEIERSQWKI EQINWMMGQE
160 170 180 190 200
IRDSVIGFFG FGGISQAIAK RLQCWDVAKI IYHTRTRKEN DGDFKAEHVS
210 220 230 240 250
FEQLLQESDF LVVAAPLTNE TREKFNGKAF NLMKRSSVFV NVARGGLVNQ
260 270 280 290 300
TDLHDALTNG TISAAGLDVT TPEPLPANSP LLNVPNFILP HMGTQTMKTT
310 320
IEMGLLAANN ILNAIEGKPM IRPAY
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ9VII9 | Q9VII9_DROME | LD14730p | Dmel\CG31673 BcDNA:LD14730, CCG31673, CG9332, CG31673, Dmel_CG31673 | 326 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AHN54624.1 |
RefSeqi | NP_001286110.1, NM_001299181.1 |
UniGenei | Dm.13891 |
Genome annotation databases
EnsemblMetazoai | FBtr0339562; FBpp0308642; FBgn0051673 |
GeneIDi | 35348 |
KEGGi | dme:Dmel_CG31673 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE014134 Genomic DNA Translation: AHN54624.1 |
RefSeqi | NP_001286110.1, NM_001299181.1 |
UniGenei | Dm.13891 |
3D structure databases
ProteinModelPortali | X2J9A5 |
SMRi | X2J9A5 |
ModBasei | Search... |
MobiDBi | Search... |
Proteomic databases
PRIDEi | X2J9A5 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblMetazoai | FBtr0339562; FBpp0308642; FBgn0051673 |
GeneIDi | 35348 |
KEGGi | dme:Dmel_CG31673 |
Organism-specific databases
FlyBasei | FBgn0051673 CG31673 |
Phylogenomic databases
eggNOGi | KOG0069 Eukaryota COG1052 LUCA |
GeneTreei | ENSGT00940000170865 |
OrthoDBi | 1378766at2759 |
Miscellaneous databases
GenomeRNAii | 35348 |
Gene expression databases
Bgeei | FBgn0051673 Expressed in 31 organ(s), highest expression level in adult Malpighian tubule (Drosophila) |
ExpressionAtlasi | X2J9A5 baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | X2J9A5_DROME | |
Accessioni | X2J9A5Primary (citable) accession number: X2J9A5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 11, 2014 |
Last sequence update: | June 11, 2014 | |
Last modified: | January 16, 2019 | |
This is version 46 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |