Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 27 (12 Aug 2020)
Sequence version 1 (14 May 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Endonuclease

Gene
N/A
Organism
Acyrthosiphon pisum (Pea aphid)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
EndonucleaseARBA annotation
Alternative name(s):
Reverse transcriptaseARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcyrthosiphon pisum (Pea aphid)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7029 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeMacrosiphiniAcyrthosiphon
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007819 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 189Reverse transcriptaseInterPro annotationAdd BLAST185
Domaini678 – 837Integrase catalyticInterPro annotationAdd BLAST160

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni409 – 446DisorderedSequence analysisAdd BLAST38
Regioni1596 – 1652DisorderedSequence analysisAdd BLAST57

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili156 – 176Sequence analysisAdd BLAST21
Coiled coili308 – 328Sequence analysisAdd BLAST21
Coiled coili854 – 874Sequence analysisAdd BLAST21
Coiled coili1090 – 1110Sequence analysisAdd BLAST21
Coiled coili1519 – 1539Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi409 – 427PolarSequence analysisAdd BLAST19
Compositional biasi1617 – 1644AcidicSequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0017, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_242435_0_0_1

Database of Orthologous Groups

More...
OrthoDBi
1416296at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit
3.30.70.270, 2 hits
3.40.220.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR022048, Envelope_fusion-like
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR043472, Macro_dom-like
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR041577, RT_RNaseH_2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12259, Baculo_F, 1 hit
PF17921, Integrase_H2C2, 1 hit
PF17919, RT_RNaseH_2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52949, SSF52949, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS50878, RT_POL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

X1WLD3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEALEREGVI TASESLWNAP LLVVPKKPDV NGQVKYRVCV DFRRLNEVTI
60 70 80 90 100
GDAFPLPNIV DILDQLGRSK YYSTLDSTHG YHQIPMDPSD RSKTAFSTDR
110 120 130 140 150
GHFEFERMPF GLKGAPGTLQ KLMNKVLIGI NGIKVFVYLD DIIIYAKDLN
160 170 180 190 200
DHSQKITEIF QRLRKYNLKL QQLKCEFLRK EVNYLGHQIT DEGVKPDPQK
210 220 230 240 250
ISCVKQFPIP RNVKEVKFFL GLSGYYRKFI RNYGRIAKPL TFLLKKDVTF
260 270 280 290 300
RWSDLCQQSF EQLKDLSTQA PILQYPDFSK TFNLTCGASE YAIGCVLSQG
310 320 330 340 350
PIGKDLPIAF ASRTLNKAEV NYNTTEKELT SIVWGIKMYR PYLFGQKFNI
360 370 380 390 400
ITNHRVLVWL FNITDPGSRL TRWCLKLEEY QYTIHFKPGV NNTNADALSR
410 420 430 440 450
IQIVTTRAQT SSSHYNQSEP PETQETSLKS VDNEHPDLES NGEGDTGYQA
460 470 480 490 500
FLKADETKLG PTKNIAERTG DLFSTDAEIS LAHCVSADFK ARKGIAFEFR
510 520 530 540 550
NRFGKVNELH RQKCQITEIA TINVSNHQVF YIITKEFSWQ KTSYEILFQS
560 570 580 590 600
LQNLKSICVN YKVTHLACPR LDCNLDGLKW VVVRNMLRYI FRDSSVYIQI
610 620 630 640 650
YTRDEITTDD KPQIIKEFHK NPLGGHQGVT RTYNKITQQY QWQGMRAQIR
660 670 680 690 700
EYIKKYPACQ INKTPNQTIK KPMVITTTAS KPFEKVFVDI VGPLNKSYHG
710 720 730 740 750
NSYILTLIDD FSKFTWACAM KDHEANTVAQ HFVTQFVCLH GQPESLVTDC
760 770 780 790 800
GTEFLNKVFK EVCKLLNISQ TSTTPYHLQS NGSLERSHRT LGEYLRNYSG
810 820 830 840 850
KNPQNWDIHV PYAMYCHNST VHTSTGFQPH EVVYGYPLSI PNSLSRKPEP
860 870 880 890 900
QYNYQDYQYE MKRLMQEMHQ MVTEQRMKSK QKSQERYNRT AVPLQINEGD
910 920 930 940 950
KVIISLVCCG LSNSQSGRFQ VTSFQNSAGL YFEAMGPLRI SYTNWDFITY
960 970 980 990 1000
VNLTTYYIKY QILRKFHDQT GDVCIQLKKR EDSILTSACT DFIQSTFPFM
1010 1020 1030 1040 1050
QEIESNFNSV VRIFGSDHRT SEHPNRQPCG LINAVGRLAN ILFGVCSDQD
1060 1070 1080 1090 1100
AEFFYKNIED LARSEDKHVH LSQEQIRIVS SVMNNVNYTM HELLTDDQKL
1110 1120 1130 1140 1150
QQNINRIEEQ SRRSVATINV LEIQNTFLEH TAILKVFLNQ FAWETQNLQS
1160 1170 1180 1190 1200
IVNSALNGLM HTNAQYLAIS DTNEYHFSLT DDQYEKCETL FSFKLCVNHE
1210 1220 1230 1240 1250
AISKSKHQEN YQATSNYTVE SNEKCAKTDA VDTDLPIVLE DKTENYNITY
1260 1270 1280 1290 1300
FIKPKPTSLK YFFKLHPVQP CDDSTLPFNS RKAFIRTYKT VRTWCTYDKS
1310 1320 1330 1340 1350
NKKMFCSVCL AFSVETNPFV CGMTDWKHIY QRITEHENSK SHVQCCEAYF
1360 1370 1380 1390 1400
MHCHQKDISS LLNSNQMHLH REEVKKNRQI LERIIEVIKI IGKRGLSVRA
1410 1420 1430 1440 1450
KRNEAAYFLR DPALDHGTFL EMIMLLNKTE NYNITYFIKP KPTSLKYFFK
1460 1470 1480 1490 1500
LHPVQPCDDS TLPFNSRKAF IRTYKTVRTW CTYDKSNKKM FCSVCLAFSV
1510 1520 1530 1540 1550
EINPFVCGMT DWKHIYQRIT EHENSKSHLS EEASEARNKH YRQYRLHFAR
1560 1570 1580 1590 1600
KFSRVDCNRD ILHRLLLSSD PYISNCRQRQ HKKTEPFSKE AVNLMIANAP
1610 1620 1630 1640 1650
SIPPTEDDRD SGRNMEDTEE GDYEEENDKE DDDEEEDEYD DGENDDKQYN

SN
Length:1,652
Mass (Da):191,819
Last modified:May 14, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iADDE71E29EABF17A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
ABLF02011604 Genomic DNA No translation available.
ABLF02041632 Genomic DNA No translation available.

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
ACYPI061196-RA; ACYPI061196-PA; ACYPI061196

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABLF02011604 Genomic DNA No translation available.
ABLF02041632 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiACYPI061196-RA; ACYPI061196-PA; ACYPI061196

Phylogenomic databases

eggNOGiKOG0017, Eukaryota
HOGENOMiCLU_242435_0_0_1
OrthoDBi1416296at2759

Family and domain databases

Gene3Di3.30.420.10, 1 hit
3.30.70.270, 2 hits
3.40.220.10, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR022048, Envelope_fusion-like
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR043472, Macro_dom-like
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR041577, RT_RNaseH_2
PfamiView protein in Pfam
PF12259, Baculo_F, 1 hit
PF17921, Integrase_H2C2, 1 hit
PF17919, RT_RNaseH_2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit
SUPFAMiSSF52949, SSF52949, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS50878, RT_POL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiX1WLD3_ACYPI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: X1WLD3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: August 12, 2020
This is version 27 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported, Transposable elementARBA annotation
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again