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Entry version 28 (02 Jun 2021)
Sequence version 1 (14 May 2014)
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Protein
Submitted name:

Si:ch211-106e7.2

Gene

si:ch211-106e7.2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Si:ch211-106e7.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:si:ch211-106e7.2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 25

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-031116-72, si:ch211-106e7.2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000097414, Expressed in blastula and 35 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 22DisorderedSequence analysisAdd BLAST22
Regioni176 – 217DisorderedSequence analysisAdd BLAST42
Regioni303 – 334DisorderedSequence analysisAdd BLAST32
Regioni354 – 379DisorderedSequence analysisAdd BLAST26
Regioni778 – 824DisorderedSequence analysisAdd BLAST47
Regioni1242 – 1308DisorderedSequence analysisAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 15Polar residuesSequence analysisAdd BLAST15
Compositional biasi303 – 324Polar residuesSequence analysisAdd BLAST22
Compositional biasi364 – 379Polar residuesSequence analysisAdd BLAST16
Compositional biasi1242 – 1267Acidic residuesSequence analysisAdd BLAST26
Compositional biasi1268 – 1304Basic and acidic residuesSequence analysisAdd BLAST37

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_244427_0_0_1

Database of Orthologous Groups

More...
OrthoDBi
74303at2759

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

X1WFD0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQANSKQSGQ LQKFTPGDGT PKIIRQNIYQ QCVSTNSAKS SYPGQTTPEN
60 70 80 90 100
HLTKVTIQQA NREQNLTSSI QAKRAQENKF HPIYTLPTGI QDSQIILWNV
110 120 130 140 150
PSNCQIFVPV QNLNLPVAPT DNPPSGSHCA FKSNSSLYVQ QKTTSLAAGP
160 170 180 190 200
NISPQVKAKP IDTISRNEAR RDVNTINLNN RQQHANAPNL TPGSSKTRLS
210 220 230 240 250
LPSDLKYKPT ENASQSNSFS GCYNQVMVPE KATHANVQAL STCVQNTWAQ
260 270 280 290 300
RAIAVVTPLS PIGTTPVDAT DESANIKINA RSVQDDVQHL PNVPHTLEAC
310 320 330 340 350
TNLRDQTENK NEPTSENQQP KSAEPRLNGG CGAESPVITA KSVVQSHFAS
360 370 380 390 400
LPKLKRVEAD PEKSNSAPMQ TEPSKNINTC TITNNKTGEA ETIPFIKWPL
410 420 430 440 450
DRLHTLTNMM QQIENSQQKN VHKNDAGKEI LKLYWNGDYR KFLEAVQTGI
460 470 480 490 500
YENVMEEVFL YCSMKEPVIL RQIKSDARNR VIKDFQTLNH NEEPPKTTYK
510 520 530 540 550
SSWLNLNENV DDIDKECGYS WFYRSCQNFT EPTQNYTTTT SSEFQEAAEM
560 570 580 590 600
PSPPRFKPTA VENKVLEEAT RDKKTTPENL SVVYNGQSPS ALTINSSPKH
610 620 630 640 650
NGMVTVKNKS QTNITNTLED VTTGVKDSDQ QDVLNGMSSS ENQCCNDAKA
660 670 680 690 700
NHLVLPKYTN QSDCTTSPKL NREFAFTPEE NSASALQSAL LPVTPLAEHN
710 720 730 740 750
QHTVEMRKDV GDQTLSDKTL DSESLCKKST PMTDNCAVKP NVDHKQVISQ
760 770 780 790 800
PNTTTPLNGL ANLVRIIKKR QELLKCQNLS GKNSSLKRKH QPSSPPRLNG
810 820 830 840 850
SLCNTAGAKS PVSPNGTSAQ SDCTNPLALS PEAEVQWKSV PLTSVQKGSS
860 870 880 890 900
QILMNSDCGT HDTISKPGQE SSVTTNEEEI VEMDTSAPLK IKVLPREMAQ
910 920 930 940 950
QYFEQNMTTP PNKTDDNYSQ KCSMFIEQTT SESNTVHPLD GTSPDNEVDS
960 970 980 990 1000
SASFMINVLP HEVAKQCFAG EFMENEVISS ALEKKSCLLN SIQYTTTTKG
1010 1020 1030 1040 1050
QISMPRLEEM DKCSSKGTVV SEQTNGLGEA MAGLDGNLSK GTKRPVLTGS
1060 1070 1080 1090 1100
MNRSCNESPP KLYPVITEPC KILNESTVEM PVLDCMLKEE SVGCKTDQIY
1110 1120 1130 1140 1150
SDGLNMDTNE EINKIDALDS IQISVLSHEA AELWFAGEVE NKDLNNDTGV
1160 1170 1180 1190 1200
HISTKDQDEC QDLELNEVVV LEDVKPKRSS GKEELDSFCC LAKWFQTLDF
1210 1220 1230 1240 1250
DNGSLCMCHK KSELSEKGSK PIHDSSLDVQ TNEVEECGIE IISDTTEDSD
1260 1270 1280 1290 1300
TTEDSEMECF EIQEDSETKE DDIPKDPTMD RTENKDVSRS EEACAEETET
1310 1320 1330 1340 1350
LEQTRDGSPL KCAANATLNH NEIEQDAQVA DFKIKTSSVF LALFGSSSGT
1360 1370 1380 1390 1400
KKEVMPTKRY KGIENCEDPP ETLQITLTSN ENIKVQRKSR RCKSVESEAG
1410 1420 1430 1440 1450
VDENVPFKNM SRCENLPSNP ISELSKNAIS PTSIRKMLNP NANGKFQYKK
1460 1470 1480 1490 1500
RKRQNKCTTQ QMSMNKFVIR GKTGVSNLPH PLANVLKSKY ELGNPALMPL
1510 1520 1530 1540 1550
EGTALEFKVL PESFNFQDGA ELEMSLSTQN ATSVHDDDEA KRMKSGGSTA
1560 1570 1580 1590
QGVWSFSPLK KKRTQSNQAT DVIGPCSLFQ EFKKKYQEKR EITFKQT
Length:1,597
Mass (Da):176,827
Last modified:May 14, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7FDF78153E5A9184
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
BX323444 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
XP_002666926.3, XM_002666880.5

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000154681; ENSDARP00000128934; ENSDARG00000097414

Database of genes from NCBI RefSeq genomes

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GeneIDi
100329241

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:100329241

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323444 Genomic DNA No translation available.
RefSeqiXP_002666926.3, XM_002666880.5

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSDART00000154681; ENSDARP00000128934; ENSDARG00000097414
GeneIDi100329241
KEGGidre:100329241

Organism-specific databases

ZFINiZDB-GENE-031116-72, si:ch211-106e7.2

Phylogenomic databases

HOGENOMiCLU_244427_0_0_1
OrthoDBi74303at2759

Gene expression databases

BgeeiENSDARG00000097414, Expressed in blastula and 35 other tissues

Family and domain databases

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiX1WFD0_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: X1WFD0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: June 2, 2021
This is version 28 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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