UniProtKB - X1WDZ6 (X1WDZ6_DANRE)
Protein
Submitted name:
Synaptotagmin VIIa
Gene
syt7a
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- calcium-dependent phospholipid binding Source: GO_Central
- calcium ion binding Source: GO_Central
- clathrin binding Source: GO_Central
- phosphatidylserine binding Source: GO_Central
- SNARE binding Source: GO_Central
GO - Biological processi
- calcium-ion regulated exocytosis Source: GO_Central
- cellular response to calcium ion Source: GO_Central
- regulation of calcium ion-dependent exocytosis Source: GO_Central
- regulation of dopamine secretion Source: GO_Central
- vesicle-mediated transport Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Synaptotagmin VIIaImported |
Gene namesi | Name:syt7aImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-090601-5, syt7a |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- exocytic vesicle Source: GO_Central
- synaptic vesicle Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSDARG00000063568, Expressed in retina and 19 other tissues |
ExpressionAtlasi | X1WDZ6, baseline |
Interactioni
GO - Molecular functioni
- clathrin binding Source: GO_Central
- SNARE binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000087435 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 355 – 443 | C2InterPro annotationAdd BLAST | 89 | |
Domaini | 484 – 575 | C2InterPro annotationAdd BLAST | 92 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 47 | DisorderedSequence analysisAdd BLAST | 47 | |
Regioni | 167 – 232 | DisorderedSequence analysisAdd BLAST | 66 | |
Regioni | 275 – 312 | DisorderedSequence analysisAdd BLAST | 38 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 16 – 31 | PolyampholyteSequence analysisAdd BLAST | 16 | |
Compositional biasi | 32 – 47 | PolarSequence analysisAdd BLAST | 16 | |
Compositional biasi | 275 – 294 | PolarSequence analysisAdd BLAST | 20 |
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG1028, Eukaryota |
GeneTreei | ENSGT00940000157180 |
Family and domain databases
CDDi | cd08386, C2A_Synaptotagmin-7, 1 hit cd08405, C2B_Synaptotagmin-7, 1 hit |
Gene3Di | 2.60.40.150, 2 hits |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR037732, C2A_Synaptotagmin-7 IPR037741, C2B_Synaptotagmin-7 IPR001565, Synaptotagmin IPR015427, Synaptotagmin7 |
PANTHERi | PTHR10024:SF358, PTHR10024:SF358, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 2 hits |
PRINTSi | PR00360, C2DOMAIN PR00399, SYNAPTOTAGMN |
SMARTi | View protein in SMART SM00239, C2, 2 hits |
PROSITEi | View protein in PROSITE PS50004, C2, 2 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
X1WDZ6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GKRNKPGVES VGSPDSGRGR GEKKAINDLD RDFWNNNDSS SVQQRWSSYP
60 70 80 90 100
PKEFVLNISP YAPYGDPRLT LNGTVHGGQK GAAGCVLGDG GGPSRSDSVR
110 120 130 140 150
SMMTGGIKAG RWQTVQSRLH SGDFKNGNLS DHTLSSVETL DYVPSAGATP
160 170 180 190 200
RPRTLLRQQS LQQPLIQAPP PNLASRPPIS QSLGQLHTQP GGAGPGGGGG
210 220 230 240 250
AGSRNSRGEP AQHRSAGAGG RGSGNPGSVD HMMGQIKKRG LDVKSFLEGK
260 270 280 290 300
MVVLSLAIGL AEQDDFANLP DLQEVPASQE TPEKSRNMGN KPANSPKGQP
310 320 330 340 350
PDADGHSSVS DLANSLTGDM VMLSPGSEDD DHEGPVSEKL GRIQFSLGYS
360 370 380 390 400
FQDTTLTVKI LKGQDLPAKD FSGTSDPFVK IYLLPDRKHK LETKVKRKNL
410 420 430 440 450
NPHWNETFLF EGFPYEKVRE RTLYLQVLDY DRFSRNDPIG EVSIPLNKVE
460 470 480 490 500
LGQLKSFWKD LKPCSDGSGS RGDLLVSLCY NPTANTITVN IIKARNLKAM
510 520 530 540 550
DIGGTSDPYV KVWLMHKDKR VEKKKTVTIK RCLNPVFNES FPFDVPAHVL
560 570 580 590 600
RETTIIITVM DKDRLSRNDV IGKIYLSWKS GPGEVKHWKD MLSRPRTNVA
QWHALKA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketE7F578 | E7F578_DANRE | Synaptotagmin VIIa | syt7a | 381 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU855880 Genomic DNA No translation available. CU929279 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000154038; ENSDARP00000128447; ENSDARG00000063568 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU855880 Genomic DNA No translation available. CU929279 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000087435 |
Proteomic databases
PaxDbi | X1WDZ6 |
Genome annotation databases
Ensembli | ENSDART00000154038; ENSDARP00000128447; ENSDARG00000063568 |
Organism-specific databases
ZFINi | ZDB-GENE-090601-5, syt7a |
Phylogenomic databases
eggNOGi | KOG1028, Eukaryota |
GeneTreei | ENSGT00940000157180 |
Gene expression databases
Bgeei | ENSDARG00000063568, Expressed in retina and 19 other tissues |
ExpressionAtlasi | X1WDZ6, baseline |
Family and domain databases
CDDi | cd08386, C2A_Synaptotagmin-7, 1 hit cd08405, C2B_Synaptotagmin-7, 1 hit |
Gene3Di | 2.60.40.150, 2 hits |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR037732, C2A_Synaptotagmin-7 IPR037741, C2B_Synaptotagmin-7 IPR001565, Synaptotagmin IPR015427, Synaptotagmin7 |
PANTHERi | PTHR10024:SF358, PTHR10024:SF358, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 2 hits |
PRINTSi | PR00360, C2DOMAIN PR00399, SYNAPTOTAGMN |
SMARTi | View protein in SMART SM00239, C2, 2 hits |
PROSITEi | View protein in PROSITE PS50004, C2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | X1WDZ6_DANRE | |
Accessioni | X1WDZ6Primary (citable) accession number: X1WDZ6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 14, 2014 |
Last sequence update: | May 14, 2014 | |
Last modified: | February 10, 2021 | |
This is version 45 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |