UniProtKB - X1WBG3 (X1WBG3_DANRE)
Protein
Submitted name:
Tau tubulin kinase 1b
Gene
ttbk1b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein serine/threonine kinase activity Source: GO_Central
GO - Biological processi
- peptidyl-serine phosphorylation Source: GO_Central
- peptidyl-tyrosine phosphorylation Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Tau tubulin kinase 1bImported |
Gene namesi | Name:ttbk1bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-100609-5, ttbk1b |
Subcellular locationi
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 297 | Protein kinaseInterPro annotationAdd BLAST | 264 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 307 – 332 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 366 – 394 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 409 – 521 | DisorderedSequence analysisAdd BLAST | 113 | |
Regioni | 542 – 647 | DisorderedSequence analysisAdd BLAST | 106 | |
Regioni | 671 – 693 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 718 – 753 | DisorderedSequence analysisAdd BLAST | 36 | |
Regioni | 818 – 1048 | DisorderedSequence analysisAdd BLAST | 231 | |
Regioni | 1089 – 1219 | DisorderedSequence analysisAdd BLAST | 131 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 315 – 332 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 437 – 473 | PolyampholyteSequence analysisAdd BLAST | 37 | |
Compositional biasi | 561 – 585 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 677 – 691 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 818 – 869 | PolyampholyteSequence analysisAdd BLAST | 52 | |
Compositional biasi | 893 – 951 | PolyampholyteSequence analysisAdd BLAST | 59 | |
Compositional biasi | 963 – 977 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 978 – 1001 | PolyampholyteSequence analysisAdd BLAST | 24 | |
Compositional biasi | 1003 – 1019 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 1020 – 1037 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 1100 – 1114 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 1115 – 1200 | PolarSequence analysisAdd BLAST | 86 | |
Compositional biasi | 1203 – 1219 | PolyampholyteSequence analysisAdd BLAST | 17 |
Phylogenomic databases
GeneTreei | ENSGT00940000165311 |
OMAi | NSLPNGP |
Family and domain databases
CDDi | cd14130, STKc_TTBK1, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR042714, TTBK1_STKc |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
X1WBG3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQCVGPGVHG DENMNGAGEQ VDILPSNCLV KDRWKVLKKI GGGGFGEIYE
60 70 80 90 100
AYDLLTRENV ALKVESAQQP KQVLKMEVAV LKKLQGKNHV CKFIGCGRND
110 120 130 140 150
KFNYVVMQLQ GRNLADLRRS QPRGTFSMST TLRLGKQILE SIEAIHSVGF
160 170 180 190 200
LHRDIKPSNF AMGRLPSTCR KCYMLDFGLA RQYTNTNGEV RPPRSVAGFR
210 220 230 240 250
GTVRYASINA HKNKEMGRHD DLWSLFYMLV EFTVGQLPWR KIKDKEQVGQ
260 270 280 290 300
IKERYEHRML LKHMPAEFHI FYDHVLDLDY FTKPDYQLLM SVFENSMKDR
310 320 330 340 350
VITENEPYDW EKSGTDTALP TSTHTPPQQN TRQTAAIVGV VNVTPVPGEL
360 370 380 390 400
PRENTDDVLQ DEHLSDQENA PPALIPSRPS EPAPAAPAGE AWDETDFNRN
410 420 430 440 450
QLRISISKTQ VAAEDGDEPA GGGRSVSPAR GGEGDAQARP PRYRRVNSPE
460 470 480 490 500
SERLSGAEDR GDGADKRSRL DMLGSPSRHV YSSQPAQMLS LEGGQGERLA
510 520 530 540 550
GGRHDVSADG DQEAHSNAFI RSVPLAEEED FDSREWVMID KETELKDFLP
560 570 580 590 600
GAEPTTSGTT DEEPEELRPL EDHEERRRRV HGGAEAVVRP KTQRGMMIVA
610 620 630 640 650
EEEGAGPSPG HSSCHTLPRS CPRRRESEPF GPDGPDIAVA EPSPSFSQTR
660 670 680 690 700
MKRVDFVSGV LMFDDLREEV VKTGGSGSDG SPRSSEGSPE GAASTLLAPA
710 720 730 740 750
HRDHDQEEGS RTLVLVSAGN GQVSPGDGQG TLAALTPQGE RPVPEESEPG
760 770 780 790 800
TLSSVIKSEP RPIVMTTAAV ITSGSSSPPF TKVERTFIHI AETSHLNVMT
810 820 830 840 850
ARHRPSGFDE PISVEREEMG EEKEDRAGQL VEIERNSEGI KVEREGDEKK
860 870 880 890 900
KEESEAEKEK QEVENVIISS REEAETVFLA EQPVSIAIKE NISIETKLDD
910 920 930 940 950
EQDGVTTEKE QEQEESPSVS PEQNRDAEVE DEKDVSPPEV ESPDRKPLPQ
960 970 980 990 1000
RRSRIPVLMS EDETGSDKSS QTSQEQLQRT RKSRHQQLAR LVLERKQTHM
1010 1020 1030 1040 1050
MRSRSASSHS PTLSTTASED EAHQSDDSAK GADGKIKSRI PRPVTPIRGS
1060 1070 1080 1090 1100
YDLLKCTTLP QTQRSVSFIQ YRTNSSINPK IQKSASLHTN IHQQPPKPQL
1110 1120 1130 1140 1150
RPSKTLPPLP PSSGPSHTQG SRTATRTVTR TSAPNATRSI STSPRSYGTS
1160 1170 1180 1190 1200
RTDSPSPQRI RRQLAANETQ RQAQQPRPPV PSVSKSKPQD STTPRKSKSH
1210
PSTSTKAKKD PLESKTKTR
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE7FBX6 | E7FBX6_DANRE | Tau tubulin kinase 1b | ttbk1b | 671 | Annotation score: | ||
X1WH52 | X1WH52_DANRE | Tau tubulin kinase 1b | ttbk1b | 243 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX649523 Genomic DNA No translation available. CT027715 Genomic DNA No translation available. |
RefSeqi | XP_017207296.1, XM_017351807.1 |
Genome annotation databases
Ensembli | ENSDART00000156872; ENSDARP00000127554; ENSDARG00000056659 |
GeneIDi | 100000353 |
KEGGi | dre:100000353 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX649523 Genomic DNA No translation available. CT027715 Genomic DNA No translation available. |
RefSeqi | XP_017207296.1, XM_017351807.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000156872; ENSDARP00000127554; ENSDARG00000056659 |
GeneIDi | 100000353 |
KEGGi | dre:100000353 |
Organism-specific databases
CTDi | 100000353 |
ZFINi | ZDB-GENE-100609-5, ttbk1b |
Phylogenomic databases
GeneTreei | ENSGT00940000165311 |
OMAi | NSLPNGP |
Gene expression databases
ExpressionAtlasi | X1WBG3, baseline |
Family and domain databases
CDDi | cd14130, STKc_TTBK1, 1 hit |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR042714, TTBK1_STKc |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | X1WBG3_DANRE | |
Accessioni | X1WBG3Primary (citable) accession number: X1WBG3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 20, 2018 |
Last sequence update: | June 20, 2018 | |
Last modified: | December 2, 2020 | |
This is version 18 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |