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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Klebsiella pneumoniae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotationImported
ORF Names:AGG09_23545Imported, B1727_19705Imported, B4U21_18120Imported, B4U36_17135Imported, BL124_0008245Imported, BN49_3494Imported, BVX91_00380Imported, C3483_09435Imported, C3F39_24960Imported, C9J88_10555Imported, CPT10_23660Imported, CSC88_00315Imported, CWQ24_10475Imported, KpST82_2601Imported, PMK1_04750Imported, SM57_02591Imported
OrganismiKlebsiella pneumoniaeImported
Taxonomic identifieri573 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000067608 Componenti: Chromosome
  • UP000053587 Componenti: Unassembled WGS sequence
  • UP000234277 Componenti: Unassembled WGS sequence
  • UP000238271 Componenti: Unassembled WGS sequence
  • UP000215037 Componenti: Unassembled WGS sequence
  • UP000186691 Componenti: Unassembled WGS sequence
  • UP000241666 Componenti: Chromosome
  • UP000239813 Componenti: Chromosome
  • UP000196863 Componenti: Unassembled WGS sequence
  • UP000037134 Componenti: Unassembled WGS sequence
  • UP000238332 Componenti: Chromosome
  • UP000029666 Componenti: Chromosome
  • UP000032739 Componenti: Chromosome
  • UP000232092 Componenti: Chromosome
  • UP000218240 Componenti: Unassembled WGS sequence
  • UP000218464 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 87Arg_tRNA_synt_NInterPro annotationAdd BLAST87
Domaini460 – 577DALR_1InterPro annotationAdd BLAST118

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

W9B9W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALLSEK VSQALIAAGA PADCEPQVRQ SAKVQFGDYQ ANGVMAVAKK
60 70 80 90 100
LGMAPRQLAE QVLSHLDLNG IANKVEIAGP GFINIFLDPA FLADNVNRAL
110 120 130 140 150
QSERLGVTKP QAQTIVVDYS APNVAKEMHV GHLRSTIIGD ASVRTLEFLG
160 170 180 190 200
HKVIRANHVG DWGTQFGMLI AYLEKQQQEN AGEMALADLE GFYREAKKHY
210 220 230 240 250
DEDEAFAERA RSYVVKLQGG DEYFLQMWRK LVDITMSQNQ ITYDRLNVTL
260 270 280 290 300
TRDDVMGESL YNPMLPGIVA DLKAKGLAVE SEGATVVFLD EYKNKEGEPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLHA DRVLYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYVPD SVPLEHHMFG MMLGKDGKPF KTRAGGTVKL ADLLDEALER
410 420 430 440 450
ARRLVAEKNP DMSADELENL AKVVGIGAVK YADLSKNRTT DYVFDWDNML
460 470 480 490 500
AFEGNTAPYM QYAYTRVLSV FRKAGIDENA MIDAPVVIAE DREAQLAARL
510 520 530 540 550
LQFEETLSVV AREGTPHVMC AYLYDLAGLF SGFYEHCPIL SAESEETRNS
560 570
RLKLALLTAK TLKLGLDTLG IETVERM
Length:577
Mass (Da):64,242
Last modified:May 14, 2014 - v1
Checksum:i93D42215E0585926
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP008929 Genomic DNA Translation: AIT04187.1
CP013322 Genomic DNA Translation: ALR27073.1
CP025037 Genomic DNA Translation: AUA50584.1
CP026392 Genomic DNA Translation: AUY21787.1
CP026586 Genomic DNA Translation: AVB71562.1
CP028180 Genomic DNA Translation: AVS26439.1
FO834906 Genomic DNA Translation: CDO15246.1
LK022720 Genomic DNA Translation: CDQ55376.1
LGJJ01000011 Genomic DNA Translation: KMW86368.1
MPYG03000062 Genomic DNA Translation: OSU24155.1
NBSD01001396 Genomic DNA Translation: OWG06557.1
MZXR01000052 Genomic DNA Translation: OXT22331.1
NSMB01000001 Genomic DNA Translation: PAX14883.1
NXFM01000026 Genomic DNA Translation: PCL79528.1
PKRL01001627 Genomic DNA Translation: PLB93395.1
PDVM01000003 Genomic DNA Translation: PPK25889.1
RefSeqiWP_004151452.1, NZ_QCWQ01000009.1

Genome annotation databases

EnsemblBacteriaiAIT04187; AIT04187; PMK1_04750
ALR27073; ALR27073; AGG09_23545
CDO15246; CDO15246; BN49_3494
ODN19143; ODN19143; BCB67_24475
SBX63279; SBX63279; SAMEA3531778_01180
KEGGikpne:KU54_009360
kpnk:BN49_3494
kpnu:LI86_09315
kpx:PMK1_04750
PATRICifig|573.1346.peg.3171

Similar proteinsi

Entry informationi

Entry nameiW9B9W2_KLEPN
AccessioniPrimary (citable) accession number: W9B9W2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: July 18, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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