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Protein
Submitted name:

ABC transporter substrate-binding protein

Gene

dppA_2

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ABC transporter substrate-binding proteinImported
Submitted name:
Peptide ABC transporter substrate-binding proteinImported
Submitted name:
Periplasmic dipeptide transport proteinImported
Submitted name:
Putative D,D-dipeptide-binding periplasmic protein DdpAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dppA_2Imported
Synonyms:dppA_1Imported
ORF Names:A8C65_10580Imported, ACU57_05000Imported, AM266_20115Imported, AM464_25330Imported, APT13_21365Imported, AUQ13_20880Imported, BET08_05940Imported, BUE81_14915Imported, BZL31_23240Imported, C5N07_23345Imported, CA593_20465Imported, DNQ41_11865Imported, EL75_2284Imported, EL79_2287Imported, EL80_2296Imported, NCTC13462_06157Imported, NCTC9010_03445Imported, NCTC9037_02830Imported, NCTC9058_04305Imported, NCTC9060_00894Imported, NCTC9062_00640Imported, NCTC9117_03312Imported, NCTC9706_03771Imported, RK56_010185Imported, SAMEA3472047_03617Imported, SAMEA3472067_04432Imported, SAMEA3484427_02579Imported, SAMEA3484429_02287Imported, SAMEA3752557_03553Imported, SAMEA3752559_04571Imported, SAMEA3753300_04664Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000236496 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000194908 Componenti: Unassembled WGS sequence
  • UP000030018 Componenti: Unassembled WGS sequence
  • UP000030000 Componenti: Unassembled WGS sequence
  • UP000254311 Componenti: Unassembled WGS sequence
  • UP000070045 Componenti: Unassembled WGS sequence
  • UP000250448 Componenti: Unassembled WGS sequence
  • UP000250519 Componenti: Unassembled WGS sequence
  • UP000250370 Componenti: Unassembled WGS sequence
  • UP000255540 Componenti: Unassembled WGS sequence
  • UP000255292 Componenti: Unassembled WGS sequence
  • UP000252069 Componenti: Unassembled WGS sequence
  • UP000250671 Componenti: Unassembled WGS sequence
  • UP000254698 Componenti: Unassembled WGS sequence
  • UP000254460 Componenti: Unassembled WGS sequence
  • UP000254785 Componenti: Unassembled WGS sequence
  • UP000254480 Componenti: Unassembled WGS sequence
  • UP000051850 Componenti: Unassembled WGS sequence
  • UP000238978 Componenti: Unassembled WGS sequence
  • UP000186204 Componenti: Unassembled WGS sequence
  • UP000258442 Componenti: Unassembled WGS sequence
  • UP000249874 Componenti: Chromosome
  • UP000050556 Componenti: Unassembled WGS sequence
  • UP000196822 Componenti: Unassembled WGS sequence
  • UP000250737 Componenti: Unassembled WGS sequence
  • UP000029988 Componenti: Unassembled WGS sequence
  • UP000259784 Componenti: Unassembled WGS sequence
  • UP000194199 Componenti: Chromosome
  • UP000247477 Componenti: Chromosome
  • UP000251336 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501510244226 – 516Sequence analysisAdd BLAST491

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini78 – 432SBP_bac_5InterPro annotationAdd BLAST355

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105DEF Bacteria
COG0747 LUCA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030678 Peptide/Ni-bd
IPR039424 SBP_5
IPR023765 SBP_5_CS
IPR000914 SBP_5_dom

The PANTHER Classification System

More...
PANTHERi
PTHR30290 PTHR30290, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00496 SBP_bac_5, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002741 MppA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01040 SBP_BACTERIAL_5, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W8U109-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRSISFRPT LLALVLATNF PVAHAAVPKD MLVIGKAADP QTLDPAVTID
60 70 80 90 100
NNDWTVTYPS YQRLVQYKTD GDKGSTDVEG DLASSWKASD DQKEWTFTLK
110 120 130 140 150
DNAKFADGTP VTAEAVKLSF ERLLKIGQGP AEAFPKDLKI DAPDEHTVKF
160 170 180 190 200
TLSQPFAPFL YTLANDGASI INPAVLKEHA ADDARGFLAQ NTAGSGPFML
210 220 230 240 250
KSWQKGQQLV LVPNPHYPGN KPNFKRVSVK IIGESASRRL QLSRGDIDIA
260 270 280 290 300
DALPVDQLNA LKQENKVNVA EYPSLRVTYL YLNNSKAPLN QADLRRAISW
310 320 330 340 350
STDYQGMVNG ILSGNGKQMR GPIPEGMWGY DATAMQYNHD ETKAKAEWDK
360 370 380 390 400
VTSKPTSLTF LYSDNDPNWE PIALATQSSL NKLGIIVKLE KLANATMRDR
410 420 430 440 450
VGKGDYDIAI GNWSPDFADP YMFMNYWFES DKKGLPGNRS FYENSEVDKL
460 470 480 490 500
LRNALATTDQ TQRTRDYQQA QKIVIDDAAY VYLFQKNYQL AMNKEVKGFV
510
FNPMLEQVFN INTMSK
Length:516
Mass (Da):57,641
Last modified:May 14, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i86E1C32CC3E06FB9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP021175 Genomic DNA Translation: ARR35287.1
CP029741 Genomic DNA Translation: AWS65873.1
CP029973 Genomic DNA Translation: AWV10928.1
JPKH01000024 Genomic DNA Translation: KGM69572.1
JPKL01000075 Genomic DNA Translation: KGM78910.1
JPMZ01000033 Genomic DNA Translation: KGM81900.1
LDYI01000040 Genomic DNA Translation: KPO16385.1
LIVE01000041 Genomic DNA Translation: KQJ13004.1
LOOZ01000034 Genomic DNA Translation: KXR87803.1
MSEK01000096 Genomic DNA Translation: OLR86594.1
MCNL01000125 Genomic DNA Translation: ONK54540.1
MUAB01000065 Genomic DNA Translation: OUK47633.1
LYBG01000585 Genomic DNA Translation: OWD70958.1
JWSO02000009 Genomic DNA Translation: PNP00984.1
PUJR01000037 Genomic DNA Translation: PQP07247.1
QOWX01000036 Genomic DNA Translation: RCR53554.1
UARY01000011 Genomic DNA Translation: SPW90194.1
UCUN01000018 Genomic DNA Translation: SQK32550.1
UCZA01000022 Genomic DNA Translation: SQP84040.1
UCZF01000036 Genomic DNA Translation: SQP93641.1
UDGC01000012 Genomic DNA Translation: SQY39931.1
UDGL01000011 Genomic DNA Translation: SQZ11436.1
UFYM01000003 Genomic DNA Translation: STD57711.1
UGBV01000003 Genomic DNA Translation: STH75482.1
UGCT01000004 Genomic DNA Translation: STJ07424.1
UGDF01000003 Genomic DNA Translation: STJ66418.1
UGDG01000002 Genomic DNA Translation: STJ69014.1
UGDC01000003 Genomic DNA Translation: STJ80682.1
UGGJ01000005 Genomic DNA Translation: STO39516.1
UINO01000051 Genomic DNA Translation: SVF42170.1
UINP01000031 Genomic DNA Translation: SVF48381.1

NCBI Reference Sequences

More...
RefSeqi
WP_000830550.1, NZ_UILI01000040.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AOT32989; AOT32989; FORC31_2530
KGM69572; KGM69572; EL75_2284
KGM78910; KGM78910; EL80_2296
KGM81900; KGM81900; EL79_2287
KPO16385; KPO16385; ACU57_05000
KQJ13004; KQJ13004; AM266_20115
KXQ39141; KXQ39141; AUQ01_14785
OCO55765; OCO55765; AN669_0213875
ODH27271; ODH27271; A6803_22080

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.10494.peg.2768

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP021175 Genomic DNA Translation: ARR35287.1
CP029741 Genomic DNA Translation: AWS65873.1
CP029973 Genomic DNA Translation: AWV10928.1
JPKH01000024 Genomic DNA Translation: KGM69572.1
JPKL01000075 Genomic DNA Translation: KGM78910.1
JPMZ01000033 Genomic DNA Translation: KGM81900.1
LDYI01000040 Genomic DNA Translation: KPO16385.1
LIVE01000041 Genomic DNA Translation: KQJ13004.1
LOOZ01000034 Genomic DNA Translation: KXR87803.1
MSEK01000096 Genomic DNA Translation: OLR86594.1
MCNL01000125 Genomic DNA Translation: ONK54540.1
MUAB01000065 Genomic DNA Translation: OUK47633.1
LYBG01000585 Genomic DNA Translation: OWD70958.1
JWSO02000009 Genomic DNA Translation: PNP00984.1
PUJR01000037 Genomic DNA Translation: PQP07247.1
QOWX01000036 Genomic DNA Translation: RCR53554.1
UARY01000011 Genomic DNA Translation: SPW90194.1
UCUN01000018 Genomic DNA Translation: SQK32550.1
UCZA01000022 Genomic DNA Translation: SQP84040.1
UCZF01000036 Genomic DNA Translation: SQP93641.1
UDGC01000012 Genomic DNA Translation: SQY39931.1
UDGL01000011 Genomic DNA Translation: SQZ11436.1
UFYM01000003 Genomic DNA Translation: STD57711.1
UGBV01000003 Genomic DNA Translation: STH75482.1
UGCT01000004 Genomic DNA Translation: STJ07424.1
UGDF01000003 Genomic DNA Translation: STJ66418.1
UGDG01000002 Genomic DNA Translation: STJ69014.1
UGDC01000003 Genomic DNA Translation: STJ80682.1
UGGJ01000005 Genomic DNA Translation: STO39516.1
UINO01000051 Genomic DNA Translation: SVF42170.1
UINP01000031 Genomic DNA Translation: SVF48381.1
RefSeqiWP_000830550.1, NZ_UILI01000040.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAOT32989; AOT32989; FORC31_2530
KGM69572; KGM69572; EL75_2284
KGM78910; KGM78910; EL80_2296
KGM81900; KGM81900; EL79_2287
KPO16385; KPO16385; ACU57_05000
KQJ13004; KQJ13004; AM266_20115
KXQ39141; KXQ39141; AUQ01_14785
OCO55765; OCO55765; AN669_0213875
ODH27271; ODH27271; A6803_22080
PATRICifig|562.10494.peg.2768

Phylogenomic databases

eggNOGiENOG4105DEF Bacteria
COG0747 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR030678 Peptide/Ni-bd
IPR039424 SBP_5
IPR023765 SBP_5_CS
IPR000914 SBP_5_dom
PANTHERiPTHR30290 PTHR30290, 1 hit
PfamiView protein in Pfam
PF00496 SBP_bac_5, 1 hit
PIRSFiPIRSF002741 MppA, 1 hit
PROSITEiView protein in PROSITE
PS01040 SBP_BACTERIAL_5, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW8U109_ECOLX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W8U109
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: December 5, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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