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Entry version 61 (18 Sep 2019)
Sequence version 1 (14 May 2014)
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Protein
Submitted name:

D-glucarate permease

Gene

gudP

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
D-glucarate permeaseImported
Submitted name:
D-glucarate transporterImported
Submitted name:
Glucarate transporterImported
Submitted name:
MFS transporterImported
Submitted name:
Putative D-glucarate transporterImported
Submitted name:
Putative glucarate transporterImported
Submitted name:
Tet(L)_9_AY081910Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gudPImported
ORF Names:A8C65_06220Imported, ACN81_20340Imported, ACU57_24370Imported, AM464_05650Imported, AUQ13_17580Imported, BANRA_01310Imported, BANRA_04315Imported, BON93_20880Imported, BUE81_06930Imported, BvCms2454_02061Imported, BvCmsH15A_01173Imported, BvCmsHHP019_05021Imported, BvCmsKSP026_00093Imported, BW690_04930Imported, BZL31_00865Imported, C4J69_11610Imported, C5N07_06200Imported, C9E25_03280Imported, D3821_11095Imported, D3O91_13470Imported, D3Y67_06475Imported, D9H68_17295Imported, D9I18_10735Imported, D9J11_17780Imported, DAH37_01290Imported, DNQ41_19005Imported, DTL43_09400Imported, E2119_13640Imported, EAI52_12545Imported, EC1094V2_894Imported, EC3234A_48c00980Imported, EEP23_14005Imported, EL75_0904Imported, EL79_0906Imported, EL80_0909Imported, EPT01_17010Imported, ERS085365_02436Imported, ERS085416_02907Imported, ERS139211_02063Imported, EYD11_05160Imported, NCTC13462_04798Imported, NCTC9037_01234Imported, NCTC9045_01210Imported, NCTC9062_02140Imported, RK56_023210Imported, SAMEA3472047_00330Imported, SAMEA3484427_03289Imported, SAMEA3484429_03406Imported, SAMEA3752557_03049Imported, SAMEA3752559_02986Imported, SAMEA3753300_01116Imported, SK85_03033Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei17 – 34HelicalSequence analysisAdd BLAST18
Transmembranei54 – 75HelicalSequence analysisAdd BLAST22
Transmembranei87 – 105HelicalSequence analysisAdd BLAST19
Transmembranei111 – 129HelicalSequence analysisAdd BLAST19
Transmembranei150 – 173HelicalSequence analysisAdd BLAST24
Transmembranei179 – 198HelicalSequence analysisAdd BLAST20
Transmembranei255 – 280HelicalSequence analysisAdd BLAST26
Transmembranei292 – 316HelicalSequence analysisAdd BLAST25
Transmembranei328 – 347HelicalSequence analysisAdd BLAST20
Transmembranei353 – 374HelicalSequence analysisAdd BLAST22
Transmembranei386 – 408HelicalSequence analysisAdd BLAST23
Transmembranei414 – 435HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 440MFSInterPro annotationAdd BLAST420

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105DJB Bacteria
ENOG410XPWC LUCA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR000849 Sugar_P_transporter

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07690 MFS_1, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002808 Hexose_phosphate_transp, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850 MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W8TA50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSLSQAASS VEKRTNARYW IVVMLFIVTS FNYGDRATLS IAGSEMAKDI
60 70 80 90 100
GLDPVGMGYV FSAFSWAYVI GQIPGGWLLD RFGSKRVYFW SIFIWSMFTL
110 120 130 140 150
LQGFVDIFSG FGIIVALFTL RFLVGLAEAP SFPGNSRIVA AWFPAQERGT
160 170 180 190 200
AVSIFNSAQY FATVIFAPIM GWLTHEVGWS HVFFFMGGLG IVISFIWLKV
210 220 230 240 250
IHEPNQHPGV NKKELEYIAA GGALINMDQQ NTKVKVPFSV KWGQIKQLLG
260 270 280 290 300
SRMMIGVYIG QYCINALTYF FITWFPVYLV QARGMSILKA GFVASVPAVC
310 320 330 340 350
GFIGGVLGGI ISDWLMRRTG SLNIARKTPI VMGMLLSMVM VFCNYVNVEW
360 370 380 390 400
MIIGFMALAF FGKGIGALGW AVMADTAPKE ISGLSGGLFN MFGNISGIVT
410 420 430 440 450
PIAIGYIVGT TGSFNGALIY VGVHALIAVL SYLVLVGDIK RIELKPVAGQ
Length:450
Mass (Da):49,142
Last modified:May 14, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0599FACCB1BB488
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP029741 Genomic DNA Translation: AWS62459.1
CP029973 Genomic DNA Translation: AWV12200.1
CYAQ01000019 Genomic DNA Translation: CTS75139.1
CYDH01000018 Genomic DNA Translation: CTV91195.1
CYCX01000022 Genomic DNA Translation: CTW25030.1
BICV01000011 Genomic DNA Translation: GCG43371.1
BFGA01000029 Genomic DNA Translation: GCP03798.1
BFKR01000573 Genomic DNA Translation: GCQ23640.1
BGAJ01000003 Genomic DNA Translation: GDJ94509.1
JPKH01000006 Genomic DNA Translation: KGM71248.1
JPKL01000016 Genomic DNA Translation: KGM83213.1
JPMZ01000005 Genomic DNA Translation: KGM84772.1
LEUM01000018 Genomic DNA Translation: KLX95491.1
LDYI01000161 Genomic DNA Translation: KPO04844.1
LOOZ01000024 Genomic DNA Translation: KXR89041.1
ROGB01000016 Genomic DNA Translation: MGS92110.1
ROIZ01000041 Genomic DNA Translation: MGU40036.1
RNWK01000028 Genomic DNA Translation: MHU15476.1
RNVW01000038 Genomic DNA Translation: MIC25613.1
LCVH01000048 Genomic DNA Translation: OAC43291.1
LGMY01000210 Genomic DNA Translation: OKU18493.1
MSEK01000046 Genomic DNA Translation: OLR88156.1
MTKH01000027 Genomic DNA Translation: ONG31068.1
MUAB01000001 Genomic DNA Translation: OUK55305.1
LYBG01000431 Genomic DNA Translation: OWD73840.1
JWSO02000016 Genomic DNA Translation: PNO94846.1
PSSV01000009 Genomic DNA Translation: PPI93436.1
PUJR01000004 Genomic DNA Translation: PQP12033.1
PYRW01000003 Genomic DNA Translation: PSZ86862.1
CP036177 Genomic DNA Translation: QBF90344.1
QOGZ01000008 Genomic DNA Translation: RDA40180.1
QXNW01000018 Genomic DNA Translation: RHX55761.1
QZVZ01000013 Genomic DNA Translation: RJX93217.1
QZWA01000015 Genomic DNA Translation: RJY02580.1
RDDG01000026 Genomic DNA Translation: RLX80781.1
SCIR01000030 Genomic DNA Translation: RXB64552.1
LT883142 Genomic DNA Translation: SMZ43990.1
UARY01000011 Genomic DNA Translation: SPW88776.1
UCZA01000018 Genomic DNA Translation: SQP82780.1
UCZF01000005 Genomic DNA Translation: SQP85740.1
UDGC01000017 Genomic DNA Translation: SQY42051.1
UDGL01000018 Genomic DNA Translation: SQZ13279.1
UFYM01000003 Genomic DNA Translation: STD54957.1
UGBV01000003 Genomic DNA Translation: STH76893.1
UGDD01000002 Genomic DNA Translation: STJ53373.1
UINO01000002 Genomic DNA Translation: SVF08780.1
UINP01000015 Genomic DNA Translation: SVF34736.1
SNTG01000022 Genomic DNA Translation: TEW32054.1
MTYA01000121 Genomic DNA Translation: TFA48147.1
QAFI01000002 Genomic DNA Translation: TGF68293.1
UWVU01000001 Genomic DNA Translation: VCW51755.1
UWXQ01000001 Genomic DNA Translation: VCZ27309.1

NCBI Reference Sequences

More...
RefSeqi
WP_000097072.1, NZ_UYIZ01000001.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AOT31538; AOT31538; FORC31_1073
CTS75139; CTS75139; ERS085365_02436
CTV91195; CTV91195; ERS139211_02063
CTW25030; CTW25030; ERS085416_02907
KGM71248; KGM71248; EL75_0904
KGM83213; KGM83213; EL80_0909
KGM84772; KGM84772; EL79_0906
KLX95491; KLX95491; SK85_03033
KPO04844; KPO04844; ACU57_24370
KQJ12946; KQJ12946; AM266_20200
KXQ40750; KXQ40750; AUQ01_08230
OAC43291; OAC43291; EC3234A_48c00980
OCO61570; OCO61570; AN669_0208235
ODH32146; ODH32146; A6803_04605

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.10481.peg.2281

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP029741 Genomic DNA Translation: AWS62459.1
CP029973 Genomic DNA Translation: AWV12200.1
CYAQ01000019 Genomic DNA Translation: CTS75139.1
CYDH01000018 Genomic DNA Translation: CTV91195.1
CYCX01000022 Genomic DNA Translation: CTW25030.1
BICV01000011 Genomic DNA Translation: GCG43371.1
BFGA01000029 Genomic DNA Translation: GCP03798.1
BFKR01000573 Genomic DNA Translation: GCQ23640.1
BGAJ01000003 Genomic DNA Translation: GDJ94509.1
JPKH01000006 Genomic DNA Translation: KGM71248.1
JPKL01000016 Genomic DNA Translation: KGM83213.1
JPMZ01000005 Genomic DNA Translation: KGM84772.1
LEUM01000018 Genomic DNA Translation: KLX95491.1
LDYI01000161 Genomic DNA Translation: KPO04844.1
LOOZ01000024 Genomic DNA Translation: KXR89041.1
ROGB01000016 Genomic DNA Translation: MGS92110.1
ROIZ01000041 Genomic DNA Translation: MGU40036.1
RNWK01000028 Genomic DNA Translation: MHU15476.1
RNVW01000038 Genomic DNA Translation: MIC25613.1
LCVH01000048 Genomic DNA Translation: OAC43291.1
LGMY01000210 Genomic DNA Translation: OKU18493.1
MSEK01000046 Genomic DNA Translation: OLR88156.1
MTKH01000027 Genomic DNA Translation: ONG31068.1
MUAB01000001 Genomic DNA Translation: OUK55305.1
LYBG01000431 Genomic DNA Translation: OWD73840.1
JWSO02000016 Genomic DNA Translation: PNO94846.1
PSSV01000009 Genomic DNA Translation: PPI93436.1
PUJR01000004 Genomic DNA Translation: PQP12033.1
PYRW01000003 Genomic DNA Translation: PSZ86862.1
CP036177 Genomic DNA Translation: QBF90344.1
QOGZ01000008 Genomic DNA Translation: RDA40180.1
QXNW01000018 Genomic DNA Translation: RHX55761.1
QZVZ01000013 Genomic DNA Translation: RJX93217.1
QZWA01000015 Genomic DNA Translation: RJY02580.1
RDDG01000026 Genomic DNA Translation: RLX80781.1
SCIR01000030 Genomic DNA Translation: RXB64552.1
LT883142 Genomic DNA Translation: SMZ43990.1
UARY01000011 Genomic DNA Translation: SPW88776.1
UCZA01000018 Genomic DNA Translation: SQP82780.1
UCZF01000005 Genomic DNA Translation: SQP85740.1
UDGC01000017 Genomic DNA Translation: SQY42051.1
UDGL01000018 Genomic DNA Translation: SQZ13279.1
UFYM01000003 Genomic DNA Translation: STD54957.1
UGBV01000003 Genomic DNA Translation: STH76893.1
UGDD01000002 Genomic DNA Translation: STJ53373.1
UINO01000002 Genomic DNA Translation: SVF08780.1
UINP01000015 Genomic DNA Translation: SVF34736.1
SNTG01000022 Genomic DNA Translation: TEW32054.1
MTYA01000121 Genomic DNA Translation: TFA48147.1
QAFI01000002 Genomic DNA Translation: TGF68293.1
UWVU01000001 Genomic DNA Translation: VCW51755.1
UWXQ01000001 Genomic DNA Translation: VCZ27309.1
RefSeqiWP_000097072.1, NZ_UYIZ01000001.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAOT31538; AOT31538; FORC31_1073
CTS75139; CTS75139; ERS085365_02436
CTV91195; CTV91195; ERS139211_02063
CTW25030; CTW25030; ERS085416_02907
KGM71248; KGM71248; EL75_0904
KGM83213; KGM83213; EL80_0909
KGM84772; KGM84772; EL79_0906
KLX95491; KLX95491; SK85_03033
KPO04844; KPO04844; ACU57_24370
KQJ12946; KQJ12946; AM266_20200
KXQ40750; KXQ40750; AUQ01_08230
OAC43291; OAC43291; EC3234A_48c00980
OCO61570; OCO61570; AN669_0208235
ODH32146; ODH32146; A6803_04605
PATRICifig|562.10481.peg.2281

Phylogenomic databases

eggNOGiENOG4105DJB Bacteria
ENOG410XPWC LUCA

Family and domain databases

InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR000849 Sugar_P_transporter
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
PIRSFiPIRSF002808 Hexose_phosphate_transp, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW8TA50_ECOLX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W8TA50
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: September 18, 2019
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health

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