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Entry version 59 (16 Oct 2019)
Sequence version 1 (14 May 2014)
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Protein
Submitted name:

Inner membrane protein YihN

Gene

yihN

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Inner membrane protein YihNImported
Submitted name:
MFS transporterImported
Submitted name:
MFS transporter family proteinImported
Submitted name:
Major facilitator superfamily proteinImported
Submitted name:
Membrane proteinImported
Submitted name:
Resistance proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yihNImported
Synonyms:yihN_1Imported
ORF Names:AUQ13_20615Imported, BET08_12435Imported, BON93_13545Imported, BUE81_09865Imported, BvCms12BK_03472Imported, BvCms2454_03860Imported, BvCmsHHP056_00237Imported, BvCmsKKP036_02658Imported, BvCmsKKP061_00818Imported, BvCmsKSP011_02792Imported, BvCmsKSP024_00713Imported, BvCmsKSP026_02939Imported, BvCmsKSP045_01217Imported, BvCmsKSP067_00873Imported, BvCmsNSP047_00696Imported, C4J69_10170Imported, C5N07_19090Imported, C9Z12_14835Imported, CA593_06620Imported, D3821_15320Imported, D9J11_11980Imported, DNQ41_00680Imported, E2119_19095Imported, EAI42_02760Imported, EAI52_18650Imported, EC1094V2_4438Imported, EC3234A_72c00200Imported, EC3426_00179Imported, EEP23_17660Imported, EYD11_22405Imported, NCTC10865_06050Imported, NCTC13148_04247Imported, NCTC13462_03718Imported, NCTC9058_02024Imported, NCTC9062_03286Imported, RK56_017995Imported, SAMEA3484427_03341Imported, SAMEA3484429_03456Imported, SAMEA3752557_02784Imported, WQ89_24815Imported, WR15_05255Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei46 – 67HelicalSequence analysisAdd BLAST22
Transmembranei74 – 90HelicalSequence analysisAdd BLAST17
Transmembranei96 – 122HelicalSequence analysisAdd BLAST27
Transmembranei143 – 165HelicalSequence analysisAdd BLAST23
Transmembranei171 – 189HelicalSequence analysisAdd BLAST19
Transmembranei221 – 242HelicalSequence analysisAdd BLAST22
Transmembranei248 – 268HelicalSequence analysisAdd BLAST21
Transmembranei289 – 308HelicalSequence analysisAdd BLAST20
Transmembranei314 – 339HelicalSequence analysisAdd BLAST26
Transmembranei351 – 374HelicalSequence analysisAdd BLAST24
Transmembranei386 – 406HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 410MFSInterPro annotationAdd BLAST410

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105R9B Bacteria
ENOG410XQHZ LUCA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07690 MFS_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850 MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W8SYE1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLTKKKWALF SLLTLCGGTI YKLPSLKDAF YIPMQEYFHL TNGQIGNAMS
60 70 80 90 100
VNSFVTTVGF FLSIYFADKL PRRYTMSFSL IATGLLGVYL TTMPGYWGIL
110 120 130 140 150
FVWALFGVTC DMMNWPVLLK SVSRLGNSEQ QGRLFGFFET GRGIVDTVVA
160 170 180 190 200
FSALAVFTWF GSGLLGFKAG IWFYSLIVIA VGIIIFFVLN DKEEAPSVEV
210 220 230 240 250
KKEDGASKNT SMTSVLKDKT IWLIAFNVFF VYAVYCGLTF FIPFLKNIYL
260 270 280 290 300
LPVALVGAYG IINQYCLKMI GGPIGGMISD KILKSPSKYL CYTFIISTAA
310 320 330 340 350
LVLLIMLPHE SMPVYLGMAC TLGFGAIVFT QRAVFFAPIG EAKIAENKTG
360 370 380 390 400
AAMALGSFIG YAPAMFCFSL YGYILDLNPG IIGYKIVFGI MACFAFSGAV
410 420
VSVMLVKRIS QRKKEMLAAE A
Length:421
Mass (Da):46,335
Last modified:May 14, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4FD9FAAA33A8E846
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP021175 Genomic DNA Translation: ARR32804.1
CP029973 Genomic DNA Translation: AWV08970.1
BHZO01000074 Genomic DNA Translation: GCG05629.1
BFGA01000057 Genomic DNA Translation: GCL81319.1
BFKY01000013 Genomic DNA Translation: GCS29958.1
BFXJ01000077 Genomic DNA Translation: GDG96577.1
BFXY01000025 Genomic DNA Translation: GDH31035.1
BGAI01000012 Genomic DNA Translation: GDJ59034.1
BFZV01000054 Genomic DNA Translation: GDJ85278.1
BGAJ01000060 Genomic DNA Translation: GDK16357.1
BGAV01000023 Genomic DNA Translation: GDL57924.1
BGBI01000011 Genomic DNA Translation: GDO33989.1
BGEG01000025 Genomic DNA Translation: GDR36536.1
LGZN01000016 Genomic DNA Translation: KNF71016.1
LGZP01000064 Genomic DNA Translation: KNF74602.1
LOOZ01000032 Genomic DNA Translation: KXR87972.1
ROIZ01000066 Genomic DNA Translation: MGU40748.1
RNWK01000014 Genomic DNA Translation: MHU14369.1
LCVH01000072 Genomic DNA Translation: OAC40143.1
MSEK01000063 Genomic DNA Translation: OLR87546.1
MCNL01001593 Genomic DNA Translation: ONK50612.1
JWSO02000014 Genomic DNA Translation: PNO95909.1
PSSV01000007 Genomic DNA Translation: PPI94260.1
PUJR01000022 Genomic DNA Translation: PQP08348.1
CP036177 Genomic DNA Translation: QBF93447.1
QZVZ01000018 Genomic DNA Translation: RJX91472.1
RDDG01000054 Genomic DNA Translation: RLX77614.1
RDDQ01000010 Genomic DNA Translation: RLY75606.1
LT883142 Genomic DNA Translation: SMZ47530.1
UARY01000011 Genomic DNA Translation: SPW87721.1
UCZA01000016 Genomic DNA Translation: SQP82526.1
UDGC01000018 Genomic DNA Translation: SQY42154.1
UDGL01000019 Genomic DNA Translation: SQZ13331.1
UGBV01000003 Genomic DNA Translation: STH77971.1
UGCD01000002 Genomic DNA Translation: STI20622.1
UGCT01000004 Genomic DNA Translation: STJ05261.1
UGET01000004 Genomic DNA Translation: STL89186.1
LS992185 Genomic DNA Translation: SYX32987.1
SNTG01000039 Genomic DNA Translation: TEW30054.1
MTYA01000092 Genomic DNA Translation: TFA52280.1
RREH01000017 Genomic DNA Translation: TJS95176.1

NCBI Reference Sequences

More...
RefSeqi
WP_000956313.1, NZ_VIAN01000011.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
KHH07213; KHH07213; PU69_19445
KIH35641; KIH35641; PD07_13685
KLG75540; KLG75540; WR12_19680
KNF71016; KNF71016; WR15_05255
KNF74602; KNF74602; WQ89_24815
KQJ13481; KQJ13481; AM266_18290
KXQ35275; KXQ35275; AUQ01_23135
OAC40143; OAC40143; EC3234A_72c00200
OCO47651; OCO47651; AN669_0200395
ODH29371; ODH29371; A6803_14210

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.10493.peg.5286

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP021175 Genomic DNA Translation: ARR32804.1
CP029973 Genomic DNA Translation: AWV08970.1
BHZO01000074 Genomic DNA Translation: GCG05629.1
BFGA01000057 Genomic DNA Translation: GCL81319.1
BFKY01000013 Genomic DNA Translation: GCS29958.1
BFXJ01000077 Genomic DNA Translation: GDG96577.1
BFXY01000025 Genomic DNA Translation: GDH31035.1
BGAI01000012 Genomic DNA Translation: GDJ59034.1
BFZV01000054 Genomic DNA Translation: GDJ85278.1
BGAJ01000060 Genomic DNA Translation: GDK16357.1
BGAV01000023 Genomic DNA Translation: GDL57924.1
BGBI01000011 Genomic DNA Translation: GDO33989.1
BGEG01000025 Genomic DNA Translation: GDR36536.1
LGZN01000016 Genomic DNA Translation: KNF71016.1
LGZP01000064 Genomic DNA Translation: KNF74602.1
LOOZ01000032 Genomic DNA Translation: KXR87972.1
ROIZ01000066 Genomic DNA Translation: MGU40748.1
RNWK01000014 Genomic DNA Translation: MHU14369.1
LCVH01000072 Genomic DNA Translation: OAC40143.1
MSEK01000063 Genomic DNA Translation: OLR87546.1
MCNL01001593 Genomic DNA Translation: ONK50612.1
JWSO02000014 Genomic DNA Translation: PNO95909.1
PSSV01000007 Genomic DNA Translation: PPI94260.1
PUJR01000022 Genomic DNA Translation: PQP08348.1
CP036177 Genomic DNA Translation: QBF93447.1
QZVZ01000018 Genomic DNA Translation: RJX91472.1
RDDG01000054 Genomic DNA Translation: RLX77614.1
RDDQ01000010 Genomic DNA Translation: RLY75606.1
LT883142 Genomic DNA Translation: SMZ47530.1
UARY01000011 Genomic DNA Translation: SPW87721.1
UCZA01000016 Genomic DNA Translation: SQP82526.1
UDGC01000018 Genomic DNA Translation: SQY42154.1
UDGL01000019 Genomic DNA Translation: SQZ13331.1
UGBV01000003 Genomic DNA Translation: STH77971.1
UGCD01000002 Genomic DNA Translation: STI20622.1
UGCT01000004 Genomic DNA Translation: STJ05261.1
UGET01000004 Genomic DNA Translation: STL89186.1
LS992185 Genomic DNA Translation: SYX32987.1
SNTG01000039 Genomic DNA Translation: TEW30054.1
MTYA01000092 Genomic DNA Translation: TFA52280.1
RREH01000017 Genomic DNA Translation: TJS95176.1
RefSeqiWP_000956313.1, NZ_VIAN01000011.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiKHH07213; KHH07213; PU69_19445
KIH35641; KIH35641; PD07_13685
KLG75540; KLG75540; WR12_19680
KNF71016; KNF71016; WR15_05255
KNF74602; KNF74602; WQ89_24815
KQJ13481; KQJ13481; AM266_18290
KXQ35275; KXQ35275; AUQ01_23135
OAC40143; OAC40143; EC3234A_72c00200
OCO47651; OCO47651; AN669_0200395
ODH29371; ODH29371; A6803_14210
PATRICifig|562.10493.peg.5286

Phylogenomic databases

eggNOGiENOG4105R9B Bacteria
ENOG410XQHZ LUCA

Family and domain databases

InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW8SYE1_ECOLX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W8SYE1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: October 16, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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