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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Rhodococcus opacus PD630
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei386UniRule annotation1
Active sitei512UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00181

UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:Pd630_LPD02164Imported
OrganismiRhodococcus opacus PD630Imported
Taxonomic identifieri543736 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
Proteomesi
  • UP000019682 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01810

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

W8GZJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSDITGTAA WQKLRDHHAQ IQSVHLRELF EKDPARGQEL TVSAGDLYID
60 70 80 90 100
YSKHRIDRDT IGLLLELARS ADLEARRDAM FEGEHINTSE DRAVLHTALR
110 120 130 140 150
LPADASLVVD GQDVVADVHE VLDRMGDFTD RVRSGEWRGA TGERIKTVVN
160 170 180 190 200
IGIGGSDLGP VMVYRALRHY ADAGISVRFI SNVDPADLVR SLQGLDPATT
210 220 230 240 250
LFIVASKTFS TLETLTNATA ARRWLLGGLG LGNEAVAKHF VAVSTHADRV
260 270 280 290 300
AEFGIDTANM FGFWDWVGGR YSVDSAIGLS VMAAIGKERF AEFLAGFHAV
310 320 330 340 350
DEHFRTAPLE ENAPVLLGLI GLWYSNFFGA ESRAVLPYSN DLVRFPAYLQ
360 370 380 390 400
QLTMESNGKS VRADGSPVPT STGEIFWGEP GTNGQHAFYQ LLHQGTRLVP
410 420 430 440 450
SDFIGFGEPT DDLPTADGTG SMHDLLMSNF FAQTKVLAFG KTAEEIAAEG
460 470 480 490 500
TPEHLVPHKV MPGNRPSTTI LAPKLTPSVI GQLIALYEHQ VFVEGVVWGI
510 520 530 540 550
DSFDQWGVEL GKTQAVELQP VLTAADEPAA QSDSSTDSLV RWYRRQRGRA
Length:550
Mass (Da):60,070
Last modified:May 14, 2014 - v1
Checksum:i6D2668233E6F4562
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003949 Genomic DNA Translation: AHK29390.1
RefSeqiWP_005238524.1, NZ_JH377098.1

Genome annotation databases

EnsemblBacteriaiAHK29390; AHK29390; Pd630_LPD02164
KEGGiroa:Pd630_LPD02164
PATRICifig|543736.9.peg.2136

Similar proteinsi

Entry informationi

Entry nameiW8GZJ5_RHOOP
AccessioniPrimary (citable) accession number: W8GZJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: March 28, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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