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Entry version 16 (11 Dec 2019)
Sequence version 1 (16 Apr 2014)
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Protein
Submitted name:

Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM

Gene

POLR

Organism
Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DMImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POLRImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCeratitis capitata (Mediterranean fruit fly) (Tephritis capitata)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7213 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaTephritoideaTephritidaeCeratitisCeratitis

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini509 – 796Reverse transcriptaseInterPro annotationAdd BLAST288

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni14 – 50DisorderedSequence analysisAdd BLAST37
Regioni176 – 197DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili306 – 326Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001611 Leu-rich_rpt
IPR000477 RT_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00078 RVT_1, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS51450 LRR, 1 hit
PS50878 RT_POL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W8AXW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPLKKMRRI DQASDNLNNH SNHNFLEGGS SRPQNDHTLD INNNSGENRT
60 70 80 90 100
NYLLPGNVLL ASNAATNPTV SPRQRKKWTT EVNEYLLRTY LQITKLETHR
110 120 130 140 150
TLFRKRLREK FIVKYPQMDV SEQNLSDQIR AIRRHDYITE ARREQIKQEV
160 170 180 190 200
EQELRSNSDL VVGSAEVPEN TAVSRAENIL SEENNNHNSD PTSESDDSID
210 220 230 240 250
VEKVYSRFHQ NYAQYRGMPV TSLPQLPKLH NSAKLGKLVT HFDVAILPEL
260 270 280 290 300
INQEINLEEM VITIYCTAKT VTEIITNKCF DNLLQRRKQQ SNQTARKNKS
310 320 330 340 350
GGPIWLQRLD KNIEEYRRRI GKLTAFARGG ASRRLRNQVS KICKNYNIHS
360 370 380 390 400
RFETNEELPI RTLDTLKQKL RTLCTRREKY SLSMNRREHN RLFENNQKLF
410 420 430 440 450
LRRLKSQNAN TNAQSQTEQF SSEAFTAYWS SIWSQTQRHN PSASWISDMK
460 470 480 490 500
DKYCNVPTPD FSPISSQQIN SVTRKLHNWK SPGCDKIHAY WFKKLPCTHF
510 520 530 540 550
KIAEMFTKII TGVEEIPEFL TLGTTYMIPK SSNSVEPSMY RPITCLPVIY
560 570 580 590 600
KILTACISNI FYEHIEANNL IAEEQKGCIR SSQGCKEQLV IDQVVLGQAK
610 620 630 640 650
KQSRNLYAAY IDWMKAFDSV PHSWLIEVLH LYKFNPNIII FLEKIMKYWR
660 670 680 690 700
TRIKLPQVGT AQYTDQIKIS NGIFQGDSLS PLWFIISMNP LSHILRNTGY
710 720 730 740 750
GYVVKHGQNG RCRLSHLFYV DDLKLYAAKP NNLGKLLECV ATFSNDIKMP
760 770 780 790 800
IGLDKCRKIT IIKGKVMPRD NPVEPDGLDI KEMESNEAYK YLGVMQSNCV
810 820 830 840 850
DTMQMRKKLV AEFRRRLTAL CKTQLNGRNQ TYAINSFVIP VVSYSFGIIK
860 870 880 890 900
WSTTELENMQ RIIRTVMSKY KAHHPKSSVF RTTLARKDGG RGQIDIGALH
910 920 930 940 950
DKLILNLRTY FHVKSSQSEI HQAVESADDN YTPLRMNQHY ESRNTISTDE
960 970 980 990 1000
KLQRWSEMAV HGAYRKDLLS PFVDQKLSHL WLTNRAIFAE TEGTIFAMQD
1010 1020 1030 1040 1050
GVVPTRNYVK YVIRDINAPA DKCRRCNSRS ETLDHVLAGC TALANSMYLK
1060 1070 1080 1090 1100
RHNDIAKIIH MQLAQKYKFH QNKIPYYRYI PESVHEDTSI LIYYDRTVLT
1110 1120 1130 1140 1150
NATRDHNRPD IFVVDKASKV AFIIDIAVPL NKNMQKTYTE KIAKYSDLGI
1160 1170 1180 1190 1200
DAKRQWKLRK VYLLPIIVSA HGLVHINLKE NLRKLQLSDN IIFDIQKAAL
1210
LNSCHIIRNF LQ
Length:1,212
Mass (Da):140,466
Last modified:April 16, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0BD3857FA5036160
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GAMC01016897 mRNA Translation: JAB89658.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMC01016897 mRNA Translation: JAB89658.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR000477 RT_dom
PfamiView protein in Pfam
PF00078 RVT_1, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 1 hit
PS50878 RT_POL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW8AXW6_CERCA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W8AXW6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: December 11, 2019
This is version 16 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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