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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Paenibacillus pini JCM 16418
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi485MagnesiumUniRule annotation1
Metal bindingi491MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotation, RNA-bindingUniRule annotation, Transferase
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
ORF Names:JCM16418_3895Imported
OrganismiPaenibacillus pini JCM 16418Imported
Taxonomic identifieri1236976 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
Proteomesi
  • UP000019364 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini621 – 689S1 motifInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 2 hits
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

W7YYN5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKRVEMQLG GRTLILETGR LAKQANAAVT VRYGDTVVLC TVTASKDPKD
60 70 80 90 100
LDFFPLTVNY EERLYAVGKI PGGFIKREGR PSEKAILSSR LTDRPIRPLF
110 120 130 140 150
PEGFRNDVQV LNLVMSVDQD CAPDIAAMIG TSAALSISDV PFNGPIGGIA
160 170 180 190 200
VGRIDGQFII NPNVAQQEAS DLYLVVAGTK DAIMMVEAEA NEVPEEVMLE
210 220 230 240 250
AIMFGHDEIK NIVAVIEQLV VQAGKPKMEV KLHAVDATVN AEVRAFAEAR
260 270 280 290 300
IVEAVRIEEK HARQDAIDGI NNESVSFFEQ KYIETPELLK DVKEVLHDIV
310 320 330 340 350
KEEVRRLITH DKVRPDGRKL DEIRPIECDT NILPRTHGTG LFTRGQTQAL
360 370 380 390 400
SVCTLGALGD VQILDGVDPQ ETKRFMHHYN FPPFSVGEAR PLRAPGRREI
410 420 430 440 450
GHGALGERAM SKVIPSETEF PYTIRLVSEV IESNGSTSQA SICASILAMM
460 470 480 490 500
DAGVPIKAPV AGVAMGLIKD GDHVSILTDI QGMEDHLGDM DFKVAGTAEG
510 520 530 540 550
VTAIQMDIKI DGIDRSILND ALAQAKEGRL FILSKMVEAI EKPRESLSQY
560 570 580 590 600
APKIMIMNIN PDKIRDVIGA GGKIINKIIE ETGVKIDIEQ DGRVFIASTN
610 620 630 640 650
EEMNQRARAI IEGIVREVQI GEIYVGTVKR IEKFGAFVEI LPNKDGLVHI
660 670 680 690
SQLSTDRVAK VEDVIAIGDT ITVKVTEIDQ QGRINLSRKA VLTTETKA
Length:698
Mass (Da):76,427
Last modified:April 16, 2014 - v1
Checksum:iF1E690E94E628F82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BAVZ01000014 Genomic DNA Translation: GAF09741.1
RefSeqiWP_036651553.1, NZ_BAZT01000014.1

Genome annotation databases

EnsemblBacteriaiGAF09741; GAF09741; JCM16418_3895

Similar proteinsi

Entry informationi

Entry nameiW7YYN5_9BACL
AccessioniPrimary (citable) accession number: W7YYN5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: February 28, 2018
This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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