Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 37 (08 May 2019)
Sequence version 2 (11 Nov 2015)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Protein clarinet

Gene

cla-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for synapse development in the active zone of presynaptic terminals of specific neurons including serotonergic NSM neurons (PubMed:29160205). The active zone is a protein-dense neuronal region within the presynaptic bouton, from which synaptic vesicles send neurotransmitter signals across the synapse (PubMed:29160205). Plays a role in the recruitment and clustering of synaptic vesicles in the active zone of presynaptic terminals in serotonergic NSM neurons, and coordinates the release of synaptic vesicles at presynaptic terminals to regulate neurotransmission at neuromuscular junctions (PubMed:29160205). Regulates synapse number in inhibitory motor neurons and plays a role in spontaneous postsynaptic synaptic vesicle release in muscle cells (PubMed:29160205).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein clarinet1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cla-11 PublicationImported
Synonyms:tag-80Imported
ORF Names:F45E4.3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
F45E4.3a ; CE51009 ; WBGene00018468 ; cla-1
F45E4.3b ; CE51026 ; WBGene00018468 ; cla-1
F45E4.3c ; CE49484 ; WBGene00018468 ; cla-1
F45E4.3d ; CE49489 ; WBGene00018468 ; cla-1
F45E4.3e ; CE24980 ; WBGene00018468 ; cla-1
F45E4.3f ; CE24981 ; WBGene00018468 ; cla-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell projection, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi6751 – 8892Missing in wy1048; defective morphology of the active zone region of the synapse, and abnormal clustering and localization of synaptic vesicles at presynaptic terminals of serotonergic NSM neurons. Defective synaptic transmission at neuromuscular junctions with increased sensitivity to the acetylcholinesterase inhibitor Aldicarb, and a 46% reduction in the frequency of spontaneous postsynaptic currents in postsynaptic muscle cells. 1 PublicationAdd BLAST2142

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004456241 – 8922Protein clarinetAdd BLAST8922

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
W6RTA4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
W6RTA4

PeptideAtlas

More...
PeptideAtlasi
W6RTA4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the nervous system.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in the nervous system from the three-fold stage of embryonic development.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00018468 Expressed in 3 organ(s), highest expression level in multi-cellular organism

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
W6RTA4 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
cat-4Q199802EBI-2916517,EBI-311852

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
W6RTA4, 10 interactors

STRING: functional protein association networks

More...
STRINGi
6239.F45E4.3a.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
W6RTA4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8570 – 8661PDZPROSITE-ProRule annotationAdd BLAST92
Domaini8728 – 8819C2PROSITE-ProRule annotationAdd BLAST92

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili385 – 405Sequence analysisAdd BLAST21
Coiled coili7895 – 7915Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1181 Eukaryota
ENOG4111M3T LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00620000087961

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H2KYL0

Identification of Orthologs from Complete Genome Data

More...
OMAi
QLTEHDE

Database of Orthologous Groups

More...
OrthoDBi
15051at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001478 PDZ
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168 C2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239 C2, 1 hit
SM00228 PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004 C2, 1 hit
PS50106 PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative promoter usage and alternative splicing. AlignAdd to basket
Isoform aImported (identifier: W6RTA4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSWFSYFGF SKGPPLEEVR EESEEDAQVP EQVVSKNTEE EIADAINRLS
60 70 80 90 100
PEQQNLIQDV LRRAESSRKE AKVVVDAEMM RSRFRQRDSI EDSQEIDHRY
110 120 130 140 150
SLIQMDSIPE NMVTNEMEER LATTQNEDII PESSQRSPIT PRKIHEKRAS
160 170 180 190 200
ITEVTTENLR HRFQKMKSHL TTWFNSLDYD GEYIFDFTSK PEKSEKLGEL
210 220 230 240 250
TMQYIDALSQ AIMISSHIEY SHHVLSSNPK FQQMCTQFCE SIFSVAFDEL
260 270 280 290 300
TYQLLDDKVQ ETLNEYCGQI AEEALQAAFF TMISKTLSKS KECEQVLNEI
310 320 330 340 350
SSMHKSRSFE SAKQLDQLLS RIEDDRESSR KSSPYLYEVL GKSSDSPSTS
360 370 380 390 400
ASVEYRSQNS YESEISFETP DIHVEELFDT HLNEKDETKL ILKSVEDKLE
410 420 430 440 450
TTEIEGNVPK IDENLIENIQ YDSGDQEHYI WISGPLGRIN EEHEDDFEAR
460 470 480 490 500
SESSSGSMIT HSTEPKMQLN VEEYIQTMIA RVSTENEITN TSNQTANIVI
510 520 530 540 550
DPGSIDSEEI NKLAAKLVEE SILKASQEAA SDNHEKERSS ATSKADYERS
560 570 580 590 600
FDQDVTYERS SPLLEPSEEP VMESKEPELT QEEIDHIARI QSLAEQSSFE
610 620 630 640 650
QASTIPDRPP LPARLPTVDE PIVISEQHEE DRSSATSGAD YERSFDQEVT
660 670 680 690 700
YERSSPLLEP CEEPVMESKE PELTQEEIDH IARIQSLAEK SSFEQASTIP
710 720 730 740 750
DRPPLPARLP TVDEPIVISE QHEEDRSSAT SGADYERSFD QDVTYEKSSP
760 770 780 790 800
LLEPSEDPVM ESKEPELTQE EIDHIARIQS LAEKSSFEQT STIPDRPPLP
810 820 830 840 850
ARLPTVDEPI VSSEQHEEDR SSATSGADYE RSFDQDVTYE RSSPLLEPCE
860 870 880 890 900
EPVMESKEPE LTQEEIDNIA WIQSIAEQSS FEQASTIPDR PPLPVRLPTV
910 920 930 940 950
DEPIVSSEQQ EEDRSSATSG ADYERSFDQD VTYERSSPLL EPSEDPVMES
960 970 980 990 1000
KEPELTQEEI DHIAWIQSIA EQSSFEQAST VPDRPPLPVR LPTVDEPIVS
1010 1020 1030 1040 1050
SEQHEDDRSS ATSGADYERS FDQDVTYERS SPLLEPCEEP VMESKEPELT
1060 1070 1080 1090 1100
QEEIDHIAWI QSSAEQSSFE QASTVPDRPP LPVRLPTVDE PIVSSEQHEE
1110 1120 1130 1140 1150
DRSSATSGAD YERSFDQDAT YERSSPLLEP CEEPVMESRV PELTQEEIDH
1160 1170 1180 1190 1200
IARIQSLAEK SSFEQTSTIP DRPPLPARLP TVDEPIVSSE QHEEDRSSAT
1210 1220 1230 1240 1250
SGADYERSSD QEVTYERSSP LLEPCEEPVM ESKEPELTQE EIDHIAWIQS
1260 1270 1280 1290 1300
IAEQSSFEQA STVPDRPPLP VRLPTVDEPI VSSEQHEDDR SSATSGADYE
1310 1320 1330 1340 1350
RSFDQDVTYE RSSPLLEPCE EPVMESKEPE LTQEEIDHIA WIQSIAEQSS
1360 1370 1380 1390 1400
FEQASTVPDR PPLPVRLPTV DEPIVSSEQH EDDRSSATSG DDYERPFDQD
1410 1420 1430 1440 1450
FTYERSSPLL EPCEEPVMES RVPELTQEEI DHIAWIQSIA EQSSFEQAST
1460 1470 1480 1490 1500
IPDRPPLPVR LPTVDEPIVS SEQHEDDRSS ATSGADYERS SDQEVTYERS
1510 1520 1530 1540 1550
SPLLEPCEEP VMESKKPELT QEEIDHIAWI QSIAEQSSFE QASTIPDRPP
1560 1570 1580 1590 1600
LPVRLPTVDE PIVSSEQHED DRSSATSGAD YERSFDQDVT YERSSPLLEP
1610 1620 1630 1640 1650
SEDPVMESKE PELTQEEIDH IAWIQSIAEQ SSFEQASTIP DRPPLPVQLP
1660 1670 1680 1690 1700
TVDEPIVSSE QQEEDRSSAT SGADYERSFD QDVTYERSSP LLEPSEDPVM
1710 1720 1730 1740 1750
ESKEPELTQE EIDHIAWIQS IAEQSSFEQA SKIPDRPPLP VRLPTVDEPI
1760 1770 1780 1790 1800
VSSEQHEEDR SSATSGADYE RSFDQDVTYE RSSPLLEPSE EPVMESRVPE
1810 1820 1830 1840 1850
LTQEEIDHIA WIQSIAEQSS FEQASTIPDR PPLPVRLPTV DEPIVSSEQH
1860 1870 1880 1890 1900
EEDRSSATSG ADYERSSDQE VTYERSSPLL EPCEEPVMES KEPELTQEEI
1910 1920 1930 1940 1950
DHIAWIQSIA EQSSFEQAST IPDRPPLPVR LPTVDEPIVI SEQHEEDRSS
1960 1970 1980 1990 2000
ATSGADYERS FDQDVTYERS SPLLIPSEDP VMESKESELT QEEIDHIARI
2010 2020 2030 2040 2050
QSLAEQSLFE QASTIPDRPP LPVRLPTVDE PIVISEQHEG DRSSATSGAD
2060 2070 2080 2090 2100
YERSFDQDVM YERSSPLLIP SEDPVMESKE SELTQEEIDH IARIQSLAEQ
2110 2120 2130 2140 2150
SSFEQASTIP DRPPLPVRLP TVDEPIVISE QHEGDRSSAT SGADYERSFD
2160 2170 2180 2190 2200
QDVTYERSSP LLEPCDEPVM ESKEPELTQE EIDHIARIQN LAEQSSFEQA
2210 2220 2230 2240 2250
STITDRPPLP VRLPTVDEPI VISEQHEGDR SSATPGADYE RSYDQDVTYE
2260 2270 2280 2290 2300
RSSPLLEPSE VPVMVSKAAV LTQEEIDHIA IMQSLAETED RKALLEPCEE
2310 2320 2330 2340 2350
PVMESKKPEL TQEEIDHIAW IQSIAEQSSF EQASTIPDRP PLPVRLPTVD
2360 2370 2380 2390 2400
EPIVSSEQHE DDRSSATSGA DYERSIDQEV TYERSSPLLE PCEEPVMESK
2410 2420 2430 2440 2450
KPELTQEEID HIAWIQSIAE QSSFEQASTI PDRPPLPVRL PTVDEPIVSS
2460 2470 2480 2490 2500
EQHEEDRSSA TSGADYERSS DQEVTYDRSS PLLEPCEEPV MESKPELTQE
2510 2520 2530 2540 2550
EIDHIAWIQS IAEQSSFEQA STIPDRPPLP VRLPTVDEPI VSSEQHEEDR
2560 2570 2580 2590 2600
SSATSGADYE RSFDQDVTYE RSSPLLEPSE DPVMESKEPE LTQEEIDHIA
2610 2620 2630 2640 2650
WIQSIAEQSS FEQASTIPDR PPLPVRLPTV DEPIVSSEQH EDDRSSATSG
2660 2670 2680 2690 2700
TDYERSFDQD VTYERSSPLL EPCEDPVMES KEPELTQEEI DHIAWIQSIA
2710 2720 2730 2740 2750
EQSSFEQAST IPDRPPLPVR LPTVDEPIVS SEQHEDDRSS ATSGADYERS
2760 2770 2780 2790 2800
FDQDVTYERS SPLLEPSEDP VMESKEPELT QEEIDHIARI QSLAEQSSFE
2810 2820 2830 2840 2850
QASTVPDRPP LPVRLPTVDE PIVSSEQHED DRSSATSGAD YERPFDQDFT
2860 2870 2880 2890 2900
YERSSPLLEP CEEPVMESKK PELTQEEIDH IAWIQSIAEQ SSFEQASTIP
2910 2920 2930 2940 2950
DRPPLPVRLP TVDEPIVSSE QHEEDRSSAT SGADYERSFD QDVTYERSSP
2960 2970 2980 2990 3000
LLEPYEEPVM ESKVPELTQE EIDHIARIQS LAEQSSFEQA PTIPDRPPLP
3010 3020 3030 3040 3050
VRLPTVDEPI VISEQHEGDR SSATSGADYE RSFDQDVTYE RSSPLLIPSE
3060 3070 3080 3090 3100
DPGNPSEPAP TPEEIHHTAC DPSIAAPSSS FEQASTVPDR PPLPVRLPTV
3110 3120 3130 3140 3150
DEPIVSSEQH EDDRSSATSG ADYERSFDQD VTYERSSPLL EPCEEPVMES
3160 3170 3180 3190 3200
KEPELTQEEI DHIAWIQSIA EQSSFEQAST VPDRPPLPVR LPTVDEPIVS
3210 3220 3230 3240 3250
SEQHEDDRSS ATSGADYERS FDQDVTYERS SPLLEPCEEP VMESKEPELT
3260 3270 3280 3290 3300
QEEIDHIAWI QSIAEQSSFE QASTIPDRPP LPVRLPTVDE PIVSSEQHED
3310 3320 3330 3340 3350
DRSSATSGTD YERSFDQDVT YERSSPLLEP SEEPVMLSKE AELTQEEIDH
3360 3370 3380 3390 3400
IAIIQSLAEK SSFEQFGIQT GHPFLPVRIL TERQNDHDRI SEEDNTSSCS
3410 3420 3430 3440 3450
SENNIILKYS DISYDRNTPL LNSDDEFLEK DFGASAESSE PSQGNWAKFE
3460 3470 3480 3490 3500
EISSSSNAEW PTNISTYKFP SFSEKNVNED LLNKSSWDCR DNVIVDDVIE
3510 3520 3530 3540 3550
EEDENDLLGD VTYSREVNKD YWKDSSTIPL VRIECVSDEQ INVNEETPGI
3560 3570 3580 3590 3600
DKEIKSAEIS KDDNSVVSCS SENQIDHTND EHFDFGQEDS EHEELKHCSS
3610 3620 3630 3640 3650
QYSFDSSLPP FHRYVACPSI TPSEGDDGGS SETGHPTTDE CYNEDVNRQI
3660 3670 3680 3690 3700
EQYSALASLS KSVLPVVEIK IDEATSESSV LQLDDDDKSI SEQEDFIDNM
3710 3720 3730 3740 3750
DLTLKRNEDK TNITNLGASE IQQQEENEIS AQTAEVESSD SWNSKTVKML
3760 3770 3780 3790 3800
SDDSAFAEET QHVDLVSTSA TKHEDYAEEQ TLSQEEIDHI ARITAMATED
3810 3820 3830 3840 3850
NTDLQTLPTP QVRQNEPELS QKEIDHITRI AAMANKDFGM YPSIVSEHPA
3860 3870 3880 3890 3900
PVESELTQEE LDHIARITEI ASMDISTLPP PTGKPSETSL TQEELDHIAR
3910 3920 3930 3940 3950
IAEMASAEYD VPVKIFEPPE LTQEELDHIA KITAMAAQDV QLPATQRSIT
3960 3970 3980 3990 4000
HKVSLTPPPP PPSKHFEQDL TQEELDHIAR IAEMADMDYN TPFTAEPVQD
4010 4020 4030 4040 4050
EEEEPITESG SDATSGADIF DEQEDASSDR EKRSGTSFPD NAETSLEDDT
4060 4070 4080 4090 4100
AHEKSYPQLE PSEEPVMKSK EPELTQEEID HFARIQSLAE QSSFEQASTI
4110 4120 4130 4140 4150
PDRQPLPVRL PTVDEPIVIS EQHEGDRSSA TSGADYERSF DQDVTYERSS
4160 4170 4180 4190 4200
PLLEPCDEPV MESKEPELTQ EEIDHIARIQ SLAEQSSFEQ TSTIPDRQPL
4210 4220 4230 4240 4250
PVRHPTVDEP IVISGQHEED RSSATSGADY QQSFDQDDPS KRSSPLLEPN
4260 4270 4280 4290 4300
EEQMMESTQP ELTQDHSSTT ISDILIKEVD KFIPEAKFGR SFEEHDGRLI
4310 4320 4330 4340 4350
HSGNLDIDVP LESDCRKTFG QDKSESTMPT ELTEADLERV ARIHQHFDQS
4360 4370 4380 4390 4400
SFDEVVVPTS HPDDGRSSSV RSSEYLDTVT PLSSCAATPI LTNPKLVQEE
4410 4420 4430 4440 4450
LDHIAFIQKM AEQFTFDEVE TPILRQNTTS HSVSYNFVQR SCHEDVSFQK
4460 4470 4480 4490 4500
KESPALTSLK EIAESSQLTQ EELDHIASIQ QMADQPYFEE SHFIFKSDVK
4510 4520 4530 4540 4550
EEKKEDKLHH ELFVEECVAQ ESITQDDVER KPLELTQEEI DHIAKIQKLA
4560 4570 4580 4590 4600
DQSSFEQASA IQSLPTAEEP IVEKREDDKS NITSGADYQQ SFDQDVTYKR
4610 4620 4630 4640 4650
SSPLLEPSEE PVMESKEPEL TQEEIDHIAR IQSLAEQSSF EQASTIPDRP
4660 4670 4680 4690 4700
PLPVRLPTVD EPIVISEQHE GDISSATSGA DYERSLDQDV TYERSSPLLE
4710 4720 4730 4740 4750
PCDEPVMESK EPELTQEEID HIARIQSLAE QSSFEQASTI PDRPPLPVRL
4760 4770 4780 4790 4800
PTVDEPIVSS EQHEEDRSSA TSGADIERSF DIDVSQDRVS PISEHEEGVT
4810 4820 4830 4840 4850
QEEMEHIARI AAMAAEDFKH PEGNLEPEFS QPDKDHIAMM KKLEEQSKME
4860 4870 4880 4890 4900
NQELPANPII HTDQVDRQES EGSSSATSGA DIPSSFDISS PIPPEPLQDH
4910 4920 4930 4940 4950
ITTSQKLISR PSIEISNVPS RLPELSLTAV QRGSEDISSA TSGAGIERSF
4960 4970 4980 4990 5000
DGISPLPNFS EEPIMINDEM NYVLMVTHMA QKIDVQQPIQ ETSTLRKAVL
5010 5020 5030 5040 5050
CESPEDFSEA TSGADTESIS ETTANKKDSN DSNGLTEEEM KHIAEVLRKA
5060 5070 5080 5090 5100
EASSAASGMF ERDSNLPPLR RTSITYTSHF SPSVIRDLRS STSFTSVPAA
5110 5120 5130 5140 5150
SDEEEIVKGK LKREPSTQVV YTDHFLRDLQ SINAYLEKGE DGTDVTIEET
5160 5170 5180 5190 5200
SHDNESSSLP EEDEHITDVY HFDVGTSLLV QQYILQQSTF QEAAGLHISP
5210 5220 5230 5240 5250
IRRTMSAACT AEKHIDDEEN IKEREVKHAQ SHDQIKKRAG GEPNAYELLE
5260 5270 5280 5290 5300
QHSFRHTQPL LCNVDFLWRL NFAANRMTEE IADEAGRELR AHYRNVANPR
5310 5320 5330 5340 5350
ARYFSDAYDI GTDDEEEEVT ETSQAGFSVE PMRHEEQSYG LFSFFTSSKR
5360 5370 5380 5390 5400
SVSDRPRSAL AMFTNPSPSA SPSLLRKESE DRGDILNLLR RSSGADSRAS
5410 5420 5430 5440 5450
NDSSASRLPD TALVGLSEAE KQHIMSVMSR SNRNTSPMTS RRCSSALQML
5460 5470 5480 5490 5500
PEVDNLSEAE KEHIQTILEK AESKTPFMIK VPMKKQISSR TESTNSRVSS
5510 5520 5530 5540 5550
EGIDEEVENE VQRKKTIEEP IVEIPSRAVT PRNNLRVIPP PIAISHPTPP
5560 5570 5580 5590 5600
HSAKTDTGSR HSSGSSAHSQ FGFSTPSISG FKIFFDKAKT ATETLVKEIK
5610 5620 5630 5640 5650
DEVIVEVDKD KTETKPEPNV SNELTAEEFE HIRRINEMAG IDEPIQPPPI
5660 5670 5680 5690 5700
AQERRKSSVV SGLKNMFGVG KHDESELTTE EKEHIRQMSL MAEKMDEEIL
5710 5720 5730 5740 5750
DEQSKPKSTF GLKNFFGKAT QSVMHATDSV IKNVQNQSKQ SLSGLTQEEL
5760 5770 5780 5790 5800
DNIAQATESA QQESKQELTQ DEIDHIARIN AMAAEDFEQP AVNMNQGLSQ
5810 5820 5830 5840 5850
AEKDHIARIE AMAADDSQSK IIVPPPSIIQ KDIELSMEEM DHIARIAAMA
5860 5870 5880 5890 5900
DEDFTHPVKG AVAPIYDENY SRDDGAIDRF PASTATPVFA QPSEIELSEE
5910 5920 5930 5940 5950
EREHISRIAA MAEEDFNTPY VSTHPTQQIE IELTEEEKEH IARIEAMASE
5960 5970 5980 5990 6000
DLNAPSPFIQ QEQRVATMPV PINYHVEEPT LSQEEIDHIA RITAMATEDN
6010 6020 6030 6040 6050
TDLQTLPTPQ VKQNEPELSQ EEIDHITRIA AMANEDFGMY PSIVSEHPAP
6060 6070 6080 6090 6100
VESELTQEEL DHIAKITGMA SMDISTLPPP TGKPSETSLT QEELDHIARI
6110 6120 6130 6140 6150
AEMASAEYDV PVKIFEPPEL TQEELDHIAK ITAMAAQDVQ LPATQRSITH
6160 6170 6180 6190 6200
KVSLTPPPPP PSKHFEQDLT QEELDHIARI AEMADMDYNT PFTAEPVQDE
6210 6220 6230 6240 6250
EEEPITESGS DATSGADIFD EQEDASSGAS GSFDNNNAQV LTSGFSPDRV
6260 6270 6280 6290 6300
TSPAALDTTE EPQGPIMAQK TVSPTPSADS MASRKSSEYD IRSISEIRQE
6310 6320 6330 6340 6350
SESDIGKWYE EQLSFMRQSI HDEEEDVGHE IRTDVEEFPL EYVEDQLHFL
6360 6370 6380 6390 6400
EGIDVESQHH EPTTSSAFFG TGRSIGEGEK RKYGDDAVEQ QKLENYEEEE
6410 6420 6430 6440 6450
KTKSSSREAF DDGFETQREE SLRAQQTPID SLPGSRMLKR PNFGFLSNIA
6460 6470 6480 6490 6500
NDAINKAKEA GSQIQAAVPI KPSSSSSNIV NNNVFSSSKS STSLGTSAPT
6510 6520 6530 6540 6550
KSIPSPQIGI PMDGLSEEER RQIMSVMAAA DFDDSVNNVK PSTSGSSNIP
6560 6570 6580 6590 6600
AGMEDLSEAE REKIMSVMAN AEMEMGARFP PPSSQIPTRS PSVMSSSIMS
6610 6620 6630 6640 6650
ELPPGLDDLS DDERMKIMAV MAEADMQNVR KPIARGPPPM PPSTSMIPPG
6660 6670 6680 6690 6700
MEGLSEEERQ KIMSVMANAE TDSSSSVITS RQPSRSPSVA RMQPQLMPPQ
6710 6720 6730 6740 6750
QAIPIIPPGL EGLSDEERHT IMSVMAEAEF EESRSQVPSR QPSRSPSFVN
6760 6770 6780 6790 6800
PQQSFHPIPS FEPIVPPGLE DLSEEERQKI MSVMMNAEVE ESRSQLPSRQ
6810 6820 6830 6840 6850
PSRSPSVAMI QAPAVPIIPS GMEDLPEAER QKIMSVMAEA EIQNFVPSRS
6860 6870 6880 6890 6900
PSNYSMQPVP VIPHGLEDLS EAERQKILSV MAEAEIDSAK IPSRSTSSYS
6910 6920 6930 6940 6950
MPPPLPQMSQ PEITTGLEHS SEADMEFGRD SSRSHQVIPP GLENLSEEER
6960 6970 6980 6990 7000
QQIMSVMAHA ELESIIPSGH IDQPISLPRG HTGFKPAGIV NEDELFETER
7010 7020 7030 7040 7050
KQREESPTRE SGYATSTSYE RELAMGDEER MDGLLEDIIR IREGARSRRD
7060 7070 7080 7090 7100
SRDEVLHRRE EDPEVHTPEE SSTAVVTDVP SVSPVTENVP EKQTDDFDFT
7110 7120 7130 7140 7150
YSDSRFAEIV QMQEEEEAGS LQKQKVDEKP RMWETVFDGD ESELPHQDFV
7160 7170 7180 7190 7200
FNEPTTKKTS DFDFPKETDE VFEKPSEIQR IRVTKNHDVD MDEIYDNVIA
7210 7220 7230 7240 7250
TEAPSSVSQR RQPVDSETSV KSRTIQRGPT KPPPMIKITV EEETKSDSDE
7260 7270 7280 7290 7300
ESCSEDDEEY PDRVVAAPTA PAPTFEEVEN ERIRQEELGK EVLQQIMAFG
7310 7320 7330 7340 7350
EVANDEFDVQ WAKTTTSQTP STSTKPTVTA PKRSDPIPIA PSQRSKEIEE
7360 7370 7380 7390 7400
ERIRTEALEE EEFYRHGHNP FLESPEEDEV SINMEDVEYA EIARLYESAN
7410 7420 7430 7440 7450
QTMRRPGPVY TITEDESEDD GTLSNSESRL VAREKRLMDK KTADSLMAKY
7460 7470 7480 7490 7500
QKMKKVQAKQ TTTASSTSVT ATPAYAIINF SDLKTSTRTT DSNSYFETTK
7510 7520 7530 7540 7550
NIPALEIKDP KKDIPPEISA SIDKTMAEVD ALLGQVYTNE KAIPNLLCFD
7560 7570 7580 7590 7600
QSNFSNHPPT SSASTSTADD LILLKNNNSS SPSFLLPLQS SVLGSQLDSV
7610 7620 7630 7640 7650
RDDNERNENE TTSPRGLKRS PGMLLPSPTS TSIFPMPPTA AESVGAAIGA
7660 7670 7680 7690 7700
TTASMFGGIS VADPPPTMDG LTNSYKWLQN IEDDGNLANN DMGRRKLPSI
7710 7720 7730 7740 7750
PPNSSAFPPP TSVTTNVIST DTSMPSTSSG PAPTYVDDYN VTLPSDPIVA
7760 7770 7780 7790 7800
ESLLKGGSLT RRHQHQQQHQ APVYITSSAS RPPSAAGSNI FQESRPTSSL
7810 7820 7830 7840 7850
SMYQNDVILS RPGSAASNYT TASTINPTIL AGASYSSKAS SHIRQPVSVR
7860 7870 7880 7890 7900
SPRAQTGTTQ TTAASGSASN SIRPSIGSSS VTTRVPNTLA RVLLKKELKD
7910 7920 7930 7940 7950
VLIQRKQRLE ATEIEANQRH YKVQKMLITG LLPEKPEDDI PNIVKCDLPA
7960 7970 7980 7990 8000
DLVRGVHISM QPPSPAVSAF SPRRYHHPTS VASHQSHPST FKHMSKSIAC
8010 8020 8030 8040 8050
QADELPPVKP MISLRTQLDM ERRPQLMTYV GKRSAETQTE LANYESITPT
8060 8070 8080 8090 8100
VRYGSIPRSS RERTASRRYR EQQQQIYNQM PQNHNDLLEI TKKYFEDYDR
8110 8120 8130 8140 8150
QLREFGERAR RHSRRRFDFH DDDDQDDMRK NQVMHELARR KERMCASCEI
8160 8170 8180 8190 8200
LSTTDPIRTA LNPNVPMSSD YSSHVPHYGS LPRIDYPRGT RSDVRDFTYR
8210 8220 8230 8240 8250
QQHLPQQPPT NYSYNYGSLP RNFERGFSDL PPIEIENEQS FGAPPRHRSN
8260 8270 8280 8290 8300
LGYESTSMFN LSDPVYLGYD SIPMVQHQQP RVYDQIPSGY AQDTTNLNSL
8310 8320 8330 8340 8350
NQGVRGSDMV SQYASYLNSQ FQSGLQQSAQ LPQPMIPITR YDAPMSDPYV
8360 8370 8380 8390 8400
SSRSRLVDQM NQGYNSNQYH HHSTLLAPKS AQMTHIAPTY NQLAQQQGIP
8410 8420 8430 8440 8450
MQNTQMDPLM MSSGRIPSSS SQVYSRNEMN YGSRPAQSSL FEYGNRRQYG
8460 8470 8480 8490 8500
AAPPPTYDVP NVSSASDWRT TQQQGLIQQM PMQMQQQQHN TFDARWPKED
8510 8520 8530 8540 8550
ALSRMYATAS RRRAQETALT SSNKISTGSR SYARRPIRPS SYRNPEATNS
8560 8570 8580 8590 8600
MPDRHVARRT AENSRYDVKR ILLTRSYKHH NIYNDLGVRV VGGKRQMNGE
8610 8620 8630 8640 8650
LSAYVSQLHS TANNQTLGQI KIGDEVVEWN GILLRGKTFE EVERIVNKSH
8660 8670 8680 8690 8700
GEIEMVIRTY KNPSSGVYDT LPLNRNTMRD DLSPDRVPPV PMHRINGINN
8710 8720 8730 8740 8750
NSVLHHHTLS DSSCHGHIQV SLGYDGNSRL VAKIIRARGL KSRDQSRSAP
8760 8770 8780 8790 8800
NPFVKVYLLP GRKVSHKRRT RFVDSSCAPE WNQVLEYQVA PHTLNTMFLE
8810 8820 8830 8840 8850
FTVCDYQRDV DDLPLGNVQI PLADKSAINT GPRWYPLQGS YDQPIPQHYM
8860 8870 8880 8890 8900
NGTSLSQIPS IAAASKHSAA VHNHHNHNYS EVPPSILYPK GGVGTRHPDK
8910 8920
PVRHATFNYN PVSLDIGYPA IN
Length:8,922
Mass (Da):1,000,209
Last modified:November 11, 2015 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6874549BD09F2F54
GO
Isoform bImported (identifier: W6RTA4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     8516-8527: ETALTSSNKIST → GDNSPSFLIDGR
     8528-8922: Missing.

Note: Produced by alternative splicing.1 Publication
Show »
Length:8,527
Mass (Da):955,704
Checksum:iA5386AA74BCF6881
GO
Isoform cImported (identifier: W6RTA4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-6280: Missing.
     8516-8527: ETALTSSNKIST → GDNSPSFLIDGR
     8528-8922: Missing.

Note: Produced by alternative promoter usage and alternative splicing.1 Publication
Show »
Length:2,247
Mass (Da):250,740
Checksum:iA19A894F2046581D
GO
Isoform dImported (identifier: W6RTA4-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-6280: Missing.

Note: Produced by alternative promoter usage.1 Publication
Show »
Length:2,642
Mass (Da):295,245
Checksum:i80FC3FA47A0B73F1
GO
Isoform eImported (identifier: W6RTA4-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-7691: Missing.

Note: Produced by alternative promoter usage.1 Publication
Show »
Length:1,231
Mass (Da):138,652
Checksum:i8292B1AAF432490D
GO
Isoform fImported (identifier: W6RTA4-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-7691: Missing.
     8516-8527: ETALTSSNKIST → GDNSPSFLIDGR
     8528-8922: Missing.

Note: Produced by alternative promoter usage and alternative splicing.1 Publication
Show »
Length:836
Mass (Da):94,147
Checksum:i36886DCC2A3AC52C
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0599201 – 7691Missing in isoform e and isoform f. CuratedAdd BLAST7691
Alternative sequenceiVSP_0599211 – 6280Missing in isoform c and isoform d. CuratedAdd BLAST6280
Alternative sequenceiVSP_0599228516 – 8527ETALT…NKIST → GDNSPSFLIDGR in isoform b, isoform c and isoform f. CuratedAdd BLAST12
Alternative sequenceiVSP_0599238528 – 8922Missing in isoform b, isoform c and isoform f. CuratedAdd BLAST395

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD63778.1
BX284604 Genomic DNA Translation: CCD63779.1
BX284604 Genomic DNA Translation: CDM63472.1
BX284604 Genomic DNA Translation: CDM63473.1
BX284604 Genomic DNA Translation: CDM63478.2
BX284604 Genomic DNA Translation: CDM63477.2

NCBI Reference Sequences

More...
RefSeqi
NP_001294143.1, NM_001307214.1 [W6RTA4-3]
NP_001294144.1, NM_001307215.1 [W6RTA4-4]
NP_001294148.2, NM_001307219.2 [W6RTA4-1]
NP_001294149.2, NM_001307220.2 [W6RTA4-2]
NP_501237.1, NM_068836.3 [W6RTA4-5]
NP_501238.1, NM_068837.3 [W6RTA4-6]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F45E4.3a; F45E4.3a; WBGene00018468 [W6RTA4-1]
F45E4.3b; F45E4.3b; WBGene00018468 [W6RTA4-2]
F45E4.3c; F45E4.3c; WBGene00018468 [W6RTA4-3]
F45E4.3d; F45E4.3d; WBGene00018468 [W6RTA4-4]
F45E4.3e.1; F45E4.3e.1; WBGene00018468 [W6RTA4-5]
F45E4.3e.2; F45E4.3e.2; WBGene00018468 [W6RTA4-5]
F45E4.3f.1; F45E4.3f.1; WBGene00018468 [W6RTA4-6]
F45E4.3f.2; F45E4.3f.2; WBGene00018468 [W6RTA4-6]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
177539

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F45E4.3

Keywords - Coding sequence diversityi

Alternative promoter usage, Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD63778.1
BX284604 Genomic DNA Translation: CCD63779.1
BX284604 Genomic DNA Translation: CDM63472.1
BX284604 Genomic DNA Translation: CDM63473.1
BX284604 Genomic DNA Translation: CDM63478.2
BX284604 Genomic DNA Translation: CDM63477.2
RefSeqiNP_001294143.1, NM_001307214.1 [W6RTA4-3]
NP_001294144.1, NM_001307215.1 [W6RTA4-4]
NP_001294148.2, NM_001307219.2 [W6RTA4-1]
NP_001294149.2, NM_001307220.2 [W6RTA4-2]
NP_501237.1, NM_068836.3 [W6RTA4-5]
NP_501238.1, NM_068837.3 [W6RTA4-6]

3D structure databases

SMRiW6RTA4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiW6RTA4, 10 interactors
STRINGi6239.F45E4.3a.1

Proteomic databases

EPDiW6RTA4
PaxDbiW6RTA4
PeptideAtlasiW6RTA4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF45E4.3a; F45E4.3a; WBGene00018468 [W6RTA4-1]
F45E4.3b; F45E4.3b; WBGene00018468 [W6RTA4-2]
F45E4.3c; F45E4.3c; WBGene00018468 [W6RTA4-3]
F45E4.3d; F45E4.3d; WBGene00018468 [W6RTA4-4]
F45E4.3e.1; F45E4.3e.1; WBGene00018468 [W6RTA4-5]
F45E4.3e.2; F45E4.3e.2; WBGene00018468 [W6RTA4-5]
F45E4.3f.1; F45E4.3f.1; WBGene00018468 [W6RTA4-6]
F45E4.3f.2; F45E4.3f.2; WBGene00018468 [W6RTA4-6]
GeneIDi177539
KEGGicel:CELE_F45E4.3

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
177539
WormBaseiF45E4.3a ; CE51009 ; WBGene00018468 ; cla-1
F45E4.3b ; CE51026 ; WBGene00018468 ; cla-1
F45E4.3c ; CE49484 ; WBGene00018468 ; cla-1
F45E4.3d ; CE49489 ; WBGene00018468 ; cla-1
F45E4.3e ; CE24980 ; WBGene00018468 ; cla-1
F45E4.3f ; CE24981 ; WBGene00018468 ; cla-1

Phylogenomic databases

eggNOGiKOG1181 Eukaryota
ENOG4111M3T LUCA
GeneTreeiENSGT00620000087961
InParanoidiH2KYL0
OMAiQLTEHDE
OrthoDBi15051at2759

Gene expression databases

BgeeiWBGene00018468 Expressed in 3 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiW6RTA4 baseline and differential

Family and domain databases

Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF00168 C2, 1 hit
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit
PS50106 PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCLA1_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W6RTA4
Secondary accession number(s): H2KYL0
, Q9BI65, W6RT96, W6SB84, W6SB91
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 7, 2018
Last sequence update: November 11, 2015
Last modified: May 8, 2019
This is version 37 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again