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Entry version 21 (02 Jun 2021)
Sequence version 1 (16 Apr 2014)
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Protein

RSN1_7TM domain-containing protein

Gene

GSEM1_T00004240001

Organism
Phytomonas sp. isolate EM1
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.17.5.16, the calcium-dependent chloride channel (ca-clc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RSN1_7TM domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:GSEM1_T00004240001Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhytomonas sp. isolate EM1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri134006 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaDiscobaEuglenozoaKinetoplasteaMetakinetoplastinaTrypanosomatidaTrypanosomatidaePhytomonasunclassified Phytomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000027080 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei29 – 48HelicalSequence analysisAdd BLAST20
Transmembranei270 – 292HelicalSequence analysisAdd BLAST23
Transmembranei343 – 367HelicalSequence analysisAdd BLAST25
Transmembranei671 – 691HelicalSequence analysisAdd BLAST21
Transmembranei725 – 747HelicalSequence analysisAdd BLAST23
Transmembranei876 – 899HelicalSequence analysisAdd BLAST24
Transmembranei936 – 953HelicalSequence analysisAdd BLAST18
Transmembranei959 – 979HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini669 – 909RSN1_7TMInterPro annotationAdd BLAST241

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni145 – 238DisorderedSequence analysisAdd BLAST94
Regioni500 – 531DisorderedSequence analysisAdd BLAST32
Regioni1021 – 1048DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili480 – 500Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi145 – 178Polar residuesSequence analysisAdd BLAST34
Compositional biasi1021 – 1038Polar residuesSequence analysisAdd BLAST18

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
208106at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003864, RSN1_7TM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02714, RSN1_7TM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

W6KUT9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPNYDDSFWD NNDWIVFRSS LKVNLTSTII VSCTCLALFS IVFTYLCWSE
60 70 80 90 100
TLWIKRFFRI NHTLLIPPKK RGACLSARAD GVNGASHPSA RASDVRNERN
110 120 130 140 150
AATATAVDPT GWCGLSLPAH SALFSLPSFR DWISVEEELP RASIPVLPSS
160 170 180 190 200
SSAPSSPSSS PYSANTRGGV SGARSHVTSE GSLEPGAPLD CSPTSYSAAS
210 220 230 240 250
ATSERKGGPS GAPRGERGSR RHRGSEAPGE ITSLARQGST LGDLPVELEG
260 270 280 290 300
GFSRDYVDPQ SVLYIFTLKY FASVMFLGGL FVVWIIVLAV HARAEKGRFF
310 320 330 340 350
DEAASRNETC APGSKGCTPQ NTTDLKYEAA FEITVQDIPP KSWMWWIVAL
360 370 380 390 400
LNCAFCAVFT LLTVYFVRAV GRYVDVVMAR QIQHAPGYRL VCIRSGNRKQ
410 420 430 440 450
MTSVESFRRR FLHEAVYFES GSNSPRWHSW LERMYPDYIW RWIRNRGCML
460 470 480 490 500
DRSNTILWEP SKVKRVVITQ RPPSGMLTTM RRERRRVRRF QEAVVVAREE
510 520 530 540 550
QRKAARRAPS PAEAASHPPP PAGGEKGEEG DLTCIEVVPT EASRESKKEE
560 570 580 590 600
PKESGCLRVG RRIGQALKRG ARACTKPCRA RKAHVKYHED RIRSTALELN
610 620 630 640 650
RYIVEAPMQE ADFAGFVEFE DSRSALEFVN LFRARFGSFT SGAVVSIAGP
660 670 680 690 700
HQGILMGNLQ IWRVSAILRR ILMMFFFLLL VTCYTIPIAI ISSLENIAYI
710 720 730 740 750
LGYHDEFVRI YTASMPNWLI QVINSYLPVV VLALFNILLP AIIRFIVGTM
760 770 780 790 800
KLLNQREFEA KCLHLQYLFM VLSGVVFQSA LQGGLKEIAL VVTTDTKNFA
810 820 830 840 850
KTFFLDCVVP KSNVYFYAKV LYSLGLSIWI DAIDPLPFLR ALLLRGYAKT
860 870 880 890 900
QGAYNAIFAR RKPDYVDWYS FDMTTLAIGL LFHMAVPMLV PAVLLYFILR
910 920 930 940 950
YLLQRARLFD QHRAEVPVER DCTNFGITAW VIRRTMLLYI LSEIGGLVVL
960 970 980 990 1000
YVNAHTGGLV LFCLTLSVSV GLTIYVVFAT RNWTISLRRI HELSKARSDA
1010 1020 1030 1040 1050
TELDGHAERL SSVEISTKQV RELKSRAGSP QSEPPQTPVA KGNDKEEDEA
1060 1070 1080 1090 1100
REFMGNLSIV WDRPSTEGAE KIRHEGAVSM DSYATQNEPT SQIMNSGVGE
1110 1120 1130 1140 1150
VCPECEIQLR KRLSRGHACT SRYRKSCLYL PLHLRLRIID VEAEIEKMYV
1160 1170
AKYDVVQYWN KPDPVAERPA SV
Length:1,172
Mass (Da):131,621
Last modified:April 16, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i03ED04E123B9D84D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HF955089 Genomic DNA Translation: CCW64662.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CCW64662; CCW64662; GSEM1_T00004240001

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HF955089 Genomic DNA Translation: CCW64662.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

TCDBi1.A.17.5.16, the calcium-dependent chloride channel (ca-clc) family

Genome annotation databases

EnsemblProtistsiCCW64662; CCW64662; GSEM1_T00004240001

Phylogenomic databases

OrthoDBi208106at2759

Family and domain databases

InterProiView protein in InterPro
IPR003864, RSN1_7TM
PfamiView protein in Pfam
PF02714, RSN1_7TM, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW6KUT9_9TRYP
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W6KUT9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: June 2, 2021
This is version 21 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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