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Protein

Putative hydroxypyruvate isomerase

Gene

HYI

Organism
Panthera tigris altaica (Siberian tiger)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).UniRule annotation

Catalytic activityi

Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150Proton donor/acceptorUniRule annotation1
Active sitei249Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
LigandPyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydroxypyruvate isomeraseUniRule annotation (EC:5.3.1.22UniRule annotation)
Gene namesi
Name:HYIImported
OrganismiPanthera tigris altaica (Siberian tiger)Imported
Taxonomic identifieri74533 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaePantherinaePanthera

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 220AP_endonuc_2InterPro annotationAdd BLAST196

Sequence similaritiesi

Belongs to the hyi family.UniRule annotation

Phylogenomic databases

KOiK01816

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit

Sequencei

Sequence statusi: Complete.

W6FGU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPLRFSANV SWLFPELPGL PARLRAAGSS GFEAAEVAWP YSESPESLAR
60 70 80 90 100
AAREAGLRLV LINTPPGDRE KGEMGLGAVP GRQAAFREGL EQAVLYAKAL
110 120 130 140 150
GCPRIHLMAG RVPQGADRAA VRSEMETVFL ENLRHAAGVL AQESLVGLLE
160 170 180 190 200
PINTRSTDPQ YFLDTPQQAA AILQKVGRPN LQLQMDIFHW QIMDGNLTGN
210 220 230 240 250
IREFLPLVGH VQVAQVPGRG EPDSPGELNF PYLFQLLEDE GYKGFVGCEY
260 270
QPQGDTAEGL KWLRSYWDRR GRPQAGQ
Length:277
Mass (Da):30,400
Last modified:April 16, 2014 - v1
Checksum:i1F3FBFAB4A922DDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF896417 mRNA Translation: AHJ25719.1
RefSeqiNP_001277512.1, NM_001290583.1

Genome annotation databases

GeneIDi102968342
KEGGiptg:102968342

Similar proteinsi

Entry informationi

Entry nameiW6FGU6_PANTA
AccessioniPrimary (citable) accession number: W6FGU6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: March 28, 2018
This is version 12 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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