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Entry version 47 (17 Jun 2020)
Sequence version 1 (16 Apr 2014)
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Protein

Potassium transporter

Gene

HAK23

Organism
Zea mays (Maize)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Potassium transporter.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Potassium transportUniRule annotation, Transport
LigandPotassium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Potassium transporterUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HAK23Imported
Synonyms:100383367Imported
ORF Names:ZEAMMB73_Zm00001d020325Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiZea mays (Maize)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4577 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007305 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei101 – 119HelicalUniRule annotationAdd BLAST19
Transmembranei144 – 165HelicalUniRule annotationAdd BLAST22
Transmembranei235 – 253HelicalUniRule annotationAdd BLAST19
Transmembranei273 – 290HelicalUniRule annotationAdd BLAST18
Transmembranei302 – 324HelicalUniRule annotationAdd BLAST23
Transmembranei350 – 369HelicalUniRule annotationAdd BLAST20
Transmembranei381 – 401HelicalUniRule annotationAdd BLAST21
Transmembranei421 – 448HelicalUniRule annotationAdd BLAST28
Transmembranei469 – 493HelicalUniRule annotationAdd BLAST25
Transmembranei499 – 523HelicalUniRule annotationAdd BLAST25
Transmembranei530 – 552HelicalUniRule annotationAdd BLAST23
Transmembranei558 – 576HelicalUniRule annotationAdd BLAST19

Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4577.GRMZM2G036916_P01

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 59DisorderedSequence analysisAdd BLAST59
Regioni730 – 775DisorderedSequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi12 – 49PolarSequence analysisAdd BLAST38
Compositional biasi744 – 770PolarSequence analysisAdd BLAST27

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the HAK/KUP transporter (TC 2.A.72.3) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEMH Eukaryota
COG3158 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008142_2_0_1

KEGG Orthology (KO)

More...
KOi
K03549

Identification of Orthologs from Complete Genome Data

More...
OMAi
LMIMCIV

Database of Orthologous Groups

More...
OrthoDBi
332035at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003855 K+_transporter

The PANTHER Classification System

More...
PANTHERi
PTHR30540 PTHR30540, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02705 K_trans, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00794 kup, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W5U5X2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDGGIQEEP PSTRFLTPTR SGGTRWVDGS EVDSSESTPS WSLEDERSAG
60 70 80 90 100
GVSSNGGAAA ASRVSSGAFR RRFGKRPRRV DSLDVESMNV RGAHGHSSKE
110 120 130 140 150
ISMLSTLAMA FQTLGVVYGD MGTSPLYVFS DVFSKVPIKS EVEILGALSL
160 170 180 190 200
VMYTIALIPF AKYVFIVLKA NDNGEGGTFA LYSLICRYAK VSLLPNQQRV
210 220 230 240 250
DEDISSFRLK LPTPELERAI SVKDCLEKKP LFKNILLFLV LMGTSMVIGD
260 270 280 290 300
GILTPSMSVM SAVSGLQGQV PGFDTNAVVI VSIVVLLLLF SVQRFGTGKV
310 320 330 340 350
GFMFAPILAL WFINLGSIGI YNLVKYDISV VRAFNPVYIY LFFETNGIKA
360 370 380 390 400
WSALGGCVLC ITGAEAMFAD LGHFSVKSIQ VAFTAVVFPC LLIAYMGQAA
410 420 430 440 450
FLMKNPLVVE RIFYDSVPGV LFWPVFVIAT LAAMIASQAM ISATFSCIKQ
460 470 480 490 500
AMALGCFPRI KIIHTSKKVM GQIYIPVMNW FLMVMCIIIV ATFRSTNDIA
510 520 530 540 550
NAYGIAEVGV MMVSTALVTL VMLLIWQTNL FLVLCFPILF GAVEFVYLTA
560 570 580 590 600
VLSKIQEGGW LPLAFSSLFL CIMYTWNYGS VLKYQSEMRG KISLDFILDL
610 620 630 640 650
GATLGTVRVP GIGLVYNELV QGIPSIFGQL LVTLPAMHST IVFVCIKYVP
660 670 680 690 700
VPYVPLEERF LFRRVGQKDY HMFRSVARYG YKDVRKEDHG FFEQLLVESL
710 720 730 740 750
EKFLRREAQE IALEASTMEA ERDDISVVSE VPQTPAGDGD LQTPLLSDQR
760 770 780 790 800
SGDNNRMAAT DGSDPVLPSS SMSLEEDPGL EYELSALREA MASGFTYLLA
810 820 830 840 850
HGDVRARKES VFTKKFVINY FYAFLRRNCR AGTATLKVPH SNIMRVGMTY

MV
Length:852
Mass (Da):93,861
Last modified:April 16, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i66F3368CBB66C2C1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KF815921 mRNA Translation: AHH35063.1
CM007650 Genomic DNA Translation: ONM54716.1

NCBI Reference Sequences

More...
RefSeqi
XP_008651722.1, XM_008653500.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Zm00001d020325_T001; Zm00001d020325_P001; Zm00001d020325

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100383367

Gramene; a comparative resource for plants

More...
Gramenei
Zm00001d020325_T001; Zm00001d020325_P001; Zm00001d020325

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
zma:100383367

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF815921 mRNA Translation: AHH35063.1
CM007650 Genomic DNA Translation: ONM54716.1
RefSeqiXP_008651722.1, XM_008653500.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi4577.GRMZM2G036916_P01

Genome annotation databases

EnsemblPlantsiZm00001d020325_T001; Zm00001d020325_P001; Zm00001d020325
GeneIDi100383367
GrameneiZm00001d020325_T001; Zm00001d020325_P001; Zm00001d020325
KEGGizma:100383367

Phylogenomic databases

eggNOGiENOG410IEMH Eukaryota
COG3158 LUCA
HOGENOMiCLU_008142_2_0_1
KOiK03549
OMAiLMIMCIV
OrthoDBi332035at2759

Family and domain databases

InterProiView protein in InterPro
IPR003855 K+_transporter
PANTHERiPTHR30540 PTHR30540, 1 hit
PfamiView protein in Pfam
PF02705 K_trans, 1 hit
TIGRFAMsiTIGR00794 kup, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW5U5X2_MAIZE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W5U5X2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: June 17, 2020
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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