Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

PX domain-containing protein kinase-like protein

Gene

PXK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
PX domain-containing protein kinase-like proteinImported
Submitted name:
PXKImported
Gene namesi
Name:PXKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000168297.15
HGNCiHGNC:23326 PXK

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168297

PTM / Processingi

Proteomic databases

EPDiW5RWE6
PRIDEiW5RWE6

Expressioni

Gene expression databases

BgeeiENSG00000168297

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 126PXInterPro annotationAdd BLAST113
Domaini88 – 481Protein kinaseInterPro annotationAdd BLAST394
Domaini527 – 546WH2InterPro annotationAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili416 – 436Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IF7B Eukaryota
ENOG410Z20X LUCA
GeneTreeiENSGT00390000017669

Family and domain databases

CDDicd06871 PX_MONaKA, 1 hit
Gene3Di3.30.1520.10, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR037903 MONaKA_PX
IPR001683 Phox
IPR000719 Prot_kinase_dom
IPR036871 PX_dom_sf
IPR003124 WH2_dom
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00787 PX, 1 hit
PF02205 WH2, 1 hit
SMARTiView protein in SMART
SM00312 PX, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
SSF64268 SSF64268, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS50195 PX, 1 hit
PS51082 WH2, 1 hit

Sequencei

Sequence statusi: Complete.

W5RWE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFMEKPPAG KVLLDDTVPL TAAIEASQSL QSHTEYIIRV QRGISVENSW
60 70 80 90 100
QIVRRYSDFD LLNNSLQIAG LSLPLPPKKL IGNMDREFIA ERQKGLQNYL
110 120 130 140 150
NVITTNHILS NCELVKKFLD PNNYSANYTE IALQQVSMFF RSEPKWEVVE
160 170 180 190 200
PLKDIGWRIR KKYFLMKIKN QPKERLVLSW ADLGPDKYLS DKDFQCLIKL
210 220 230 240 250
LPSCLHPYIY RVTFATANES SALLIRMFNE KGTLKDLIYK AKPKDPFLKK
260 270 280 290 300
YCNPKKIQGL ELQQIKTYGR QILEVLKFLH DKGFPYGHLH ASNVMLDGDT
310 320 330 340 350
CRLLDLENSL LGLPSFYRSY FSQFRKINTL ESVDVHCFGH LLYEMTYGRP
360 370 380 390 400
PDSVPVDSFP PAPSMAVVAV LESTLSCEAC KNGMPTISRL LQMPLFSDVL
410 420 430 440 450
LTTSEKPQFK IPTKLKEALR IAKECIEKRL IEEQKQIHQH RRLTRAQSHH
460 470 480 490 500
GSEEERKKRK ILARKKSKRS ALENSEEHSA KYSNSNNSGI SALPPPPPPP
510 520 530 540 550
PPPAAPLPPA STEAPAQLSS QAVNGMSRGA LLSSIQNFQK GTLRKAKTCD

HSAPKIG
Length:557
Mass (Da):63,095
Last modified:April 16, 2014 - v1
Checksum:i23750E6FDC5FEA24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098479 Genomic DNA No translation available.
AC135507 Genomic DNA No translation available.
KF774202 mRNA Translation: AHG94944.1
RefSeqiXP_005265309.1, XM_005265252.4
UniGeneiHs.190544

Genome annotation databases

EnsembliENST00000302779; ENSP00000305045; ENSG00000168297
UCSCiuc032rpa.2 human

Similar proteinsi

Entry informationi

Entry nameiW5RWE6_HUMAN
AccessioniPrimary (citable) accession number: W5RWE6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: July 18, 2018
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health