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Protein

Importin subunit alpha

Gene

KPNA1

Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in nuclear protein import.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Importin subunit alphaUniRule annotation
Gene namesi
Name:KPNA1Imported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis
Proteomesi
  • UP000002356 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 57IBBInterPro annotationAdd BLAST57
Repeati131 – 174ARMPROSITE-ProRule annotationAdd BLAST44
Repeati174 – 202ARMPROSITE-ProRule annotationAdd BLAST29
Repeati216 – 244ARMPROSITE-ProRule annotationAdd BLAST29
Repeati343 – 374ARMPROSITE-ProRule annotationAdd BLAST32

Sequence similaritiesi

Belongs to the importin alpha family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119094
OMAiSWLLFVN
OrthoDBiEOG091G095Z

Family and domain databases

Gene3Di1.20.5.690, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032413 Arm_3
IPR000225 Armadillo
IPR002652 Importin-a_IBB
IPR036975 Importin-a_IBB_sf
IPR024931 Importing_su_alpha
PfamiView protein in Pfam
PF00514 Arm, 8 hits
PF16186 Arm_3, 1 hit
PF01749 IBB, 1 hit
PIRSFiPIRSF005673 Importin_alpha, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 8 hits
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 4 hits
PS51214 IBB, 1 hit

Sequencei

Sequence statusi: Complete.

W5QFX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV
60 70 80 90 100
ATAEEETEEE VMSDGGFHEA QINNMEMAPG GVITSDMIEM IFSNSPEQQL
110 120 130 140 150
SATQKFRKLL SKVYGETEPN PPIDEVISTP GVVARFVEFL KRKENCTLQF
160 170 180 190 200
ESAWVLTNIA SGNSLQTRIV IQAGAVPIFI ELLSSEFEDV QEQAVWALGN
210 220 230 240 250
IAGDSTMCRD YVLDCNILPP LLQLFSKQNR LTMTRNAVWA LSNLCRGKSP
260 270 280 290 300
PPEFAKVSPC LNVLSWLLFV SDTDVLADAC WALSYLSDGP NDKIQAVIDA
310 320 330 340 350
GVCRRLVELL MHNDYKVVSP ALRAVGNIVT GDDIQTQVIL NCSALQSLLH
360 370 380 390 400
LLSSPKESIK KEACWTISNI TAGNRAQIQT VIDANIFPAL ISILQTAEFR
410 420 430 440 450
TRKEAAWAIT NATSGGSAEQ IKYLVELGCI KPLCDLLTVM DSKIVQVALN
460 470 480 490 500
GLENILRLGE QEAKRNGTGI NPYCALIEEA YGLDKIEFLQ SHENQEIYQK
510 520 530 540
AFDLIEHYFG TEDEDSSIAP QVDLNQQQYI FQQCEAPMEG FQL
Length:543
Mass (Da):60,754
Last modified:April 16, 2014 - v1
Checksum:i47413C621C823C16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMGL01008660 Genomic DNA No translation available.
AMGL01008661 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOART00000021927; ENSOARP00000021625; ENSOARG00000020139

Similar proteinsi

Entry informationi

Entry nameiW5QFX7_SHEEP
AccessioniPrimary (citable) accession number: W5QFX7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: March 28, 2018
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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