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Protein

Coatomer subunit gamma

Gene
N/A
Organism
Lepisosteus oculatus (Spotted gar)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Coatomer subunit gammaUniRule annotation
OrganismiLepisosteus oculatus (Spotted gar)Imported
Taxonomic identifieri7918 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiHolosteiSemionotiformesLepisosteidaeLepisosteus
Proteomesi
  • UP000018468 Componenti: Linkage group LG8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Oligomeric complex.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 538Adaptin_NInterPro annotationAdd BLAST514
Domaini612 – 758COP-gamma_platfInterPro annotationAdd BLAST147
Domaini760 – 872Coatomer_g_CplaInterPro annotationAdd BLAST113

Sequence similaritiesi

Belongs to the COPG family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000016313
OMAiISFLGMQ
OrthoDBiEOG091G0HWQ

Family and domain databases

Gene3Di1.25.10.10, 2 hits
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

Sequencei

Sequence statusi: Complete.

W5NF14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKKFDKKDE ESGSGSNPFQ HLEKSAVLQE ARIFNETPIN PRRCLHILTK
60 70 80 90 100
IIYLLNQGEH FGTTEATEAF FAMTRLFQSN DQTLRRMCYL TIKEMANISE
110 120 130 140 150
DVIIVTSSLT KDMTGKEDVY RGPAIRALCR ITDTTMLQAI ERYMKQAIVD
160 170 180 190 200
KVPSVSSSAL VSSLHMVKMS YDVVKRWVNE AQEAASSDNI MVQYHALGLL
210 220 230 240 250
YHLRKNDRLA VSKMLNKFTK SGLKSPFAYC MLIRIASRLL EEADGGHDNP
260 270 280 290 300
LFDFIESCLR NKHEMVVYEA ASAIVHLPNC TARELAPAVS VLQLFCSSPK
310 320 330 340 350
AALRYAAVRT LNKVAMKHPS AVTACNLDLE NLITDSNRSI ATLAITTLLK
360 370 380 390 400
TGSESSVDRL MKQISSFVSE ISDEFKVVVV QAISALCQKY PRKHSVMMNF
410 420 430 440 450
LSNMLRDDGG FDYKRAIVDC IISIIEENPE SKETGLAHLC EFIEDCEHTV
460 470 480 490 500
LATKILHLLG KEGPRTPTPS KYIRFIFNRV VLESEAVRAA AVSALAKFGA
510 520 530 540 550
QNDDLLPSVL VLLQRCMMDS DDEVRDRATF YMNVLQQKQK ALNAAYIFNG
560 570 580 590 600
LSVSIPGLEK SLHQYTLEPT EKPFDMKTVP LATAPITEQK TEIAPVVTSK
610 620 630 640 650
LPEKVAPSRQ DIYQEQLAAI PEFKGLGPLF KSSEPVQLTE AETEYVVRCI
660 670 680 690 700
KHTFTNHMVF QFDCTNTLND QLLQKVVVQM EPSEAYEVVH YVPAPNLPYS
710 720 730 740 750
QPGSCYTLVR LPDDDPTAVS CTFSCTMKYL VRDCDPNTGE PDDDGYDDEY
760 770 780 790 800
VLEDLEVTVA DHIQKVLKPN FGAAWEEVGD DFEKEETFAL ASVRTLEEAV
810 820 830 840 850
NNIISFLGMQ PCERSDKVPE NKNSHVLFLA GVFRGGHDLL VRSRLALADG
860 870
VTMQVTVRSK EETPVDVILA SVG
Length:873
Mass (Da):97,605
Last modified:April 16, 2014 - v1
Checksum:i779FCC3413A1E35C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHAT01016138 Genomic DNA No translation available.
RefSeqiXP_006633341.1, XM_006633278.2

Genome annotation databases

EnsembliENSLOCT00000019255; ENSLOCP00000019223; ENSLOCG00000015612
GeneIDi102686419

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHAT01016138 Genomic DNA No translation available.
RefSeqiXP_006633341.1, XM_006633278.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSLOCT00000019255; ENSLOCP00000019223; ENSLOCG00000015612
GeneIDi102686419

Organism-specific databases

CTDi26958

Phylogenomic databases

GeneTreeiENSGT00390000016313
OMAiISFLGMQ
OrthoDBiEOG091G0HWQ

Family and domain databases

Gene3Di1.25.10.10, 2 hits
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiW5NF14_LEPOC
AccessioniPrimary (citable) accession number: W5NF14
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: November 7, 2018
This is version 30 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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