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Protein

Eukaryotic translation initiation factor 3 subunit H

Gene

EIF3H

Organism
Lepisosteus oculatus (Spotted gar)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorUniRule annotation
Biological processProtein biosynthesis

Protein family/group databases

MEROPSiM67.971

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit HUniRule annotation
Short name:
eIF3hUniRule annotation
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 3UniRule annotation
eIF-3 gammaUniRule annotation
eIF3 p40 subunitUniRule annotation
Gene namesi
Name:EIF3HUniRule annotationImported
Synonyms:EIF3S3UniRule annotation
OrganismiLepisosteus oculatus (Spotted gar)Imported
Taxonomic identifieri7918 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiHolosteiSemionotiformesLepisosteidaeLepisosteus
Proteomesi
  • UP000018468 Componenti: Linkage group LG11

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 168MPNInterPro annotationAdd BLAST135

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili262 – 282Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the eIF-3 subunit H family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00730000111042
OMAiKFNRYQQ
OrthoDBiEOG091G0E5O

Family and domain databases

CDDicd08065 MPN_eIF3h, 1 hit
HAMAPiMF_03007 eIF3h, 1 hit
InterProiView protein in InterPro
IPR027524 eIF3h
IPR000555 JAMM/MPN+_dom
IPR037518 MPN
PANTHERiPTHR10410:SF3 PTHR10410:SF3, 1 hit
PfamiView protein in Pfam
PF01398 JAB, 1 hit
SMARTiView protein in SMART
SM00232 JAB_MPN, 1 hit
PROSITEiView protein in PROSITE
PS50249 MPN, 1 hit

Sequencei

Sequence statusi: Complete.

W5M698-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARKESAAP ASTASAPAVA STTGNTLDSP VKMIQIEGLV VLKIIKHYQE
60 70 80 90 100
EGQGSEVVQG VLLGLVVEDR LEITNCFPFP QHTEDDADFD EVQYQMEMMR
110 120 130 140 150
SLRHVNIDHL HVGWYQSTYY GSFVSRALLD SQFSYQHAIE ESVVLIYDPI
160 170 180 190 200
KTAQGSLSLK AYRLTPKLME ICKEKDFSPE GLKKANVGFE CMFEEVPIVI
210 220 230 240 250
KNSHLINVLM WELEEKSTLS DKHELLNLSS SNHLEKSLQL LMDRVDDMSQ
260 270 280 290 300
DIVKYNTYSR NVSKQQQQKH QYLQRRQQEN AQRQSRGEPL LPEEDMSKMF
310 320 330 340
KPPQPPPRMD TLLIAGQINT YCQNIKEFTS QNLGKLFMAE ALQDNSS
Length:347
Mass (Da):39,550
Last modified:April 16, 2014 - v1
Checksum:i47ED06D6DC5A4EF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHAT01012168 Genomic DNA No translation available.
AHAT01012169 Genomic DNA No translation available.
AHAT01012170 Genomic DNA No translation available.
AHAT01012171 Genomic DNA No translation available.
AHAT01012172 Genomic DNA No translation available.
AHAT01012173 Genomic DNA No translation available.
RefSeqiXP_006635632.1, XM_006635569.2

Genome annotation databases

EnsembliENSLOCT00000003914; ENSLOCP00000003906; ENSLOCG00000003303
GeneIDi102689737

Similar proteinsi

Entry informationi

Entry nameiW5M698_LEPOC
AccessioniPrimary (citable) accession number: W5M698
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: June 20, 2018
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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