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Protein
Submitted name:

Cholinergic receptor, nicotinic, gamma

Gene
N/A
Organism
Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Cholinergic receptor, nicotinic, gammaImported
OrganismiAstyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus)Imported
Taxonomic identifieri7994 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCharaciformesCharacoideiCharacidaeCharacidae incertae sedisAstyanax cladeAstyanax
Proteomesi
  • UP000018467 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei246 – 269HelicalSequence analysisAdd BLAST24
Transmembranei281 – 300HelicalSequence analysisAdd BLAST20
Transmembranei312 – 333HelicalSequence analysisAdd BLAST22
Transmembranei482 – 504HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 245Neur_chan_LBDInterPro annotationAdd BLAST218
Domaini252 – 499Neur_chan_membInterPro annotationAdd BLAST248

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000144023
OMAiEEWFLVG
OrthoDBiEOG091G0R20

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

W5LBI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LPGNSSLILY WVYVCVYSLG VVCNLEGDLH MDLMAGYSKN IRPMENNGDI
60 70 80 90 100
TEVKLKMTLT NLISLNEKEE TLTTCVWVEM QWYDYRLRWA NRPGFEGYEN
110 120 130 140 150
ITRTRIPSTS IWLPDIILEN NVDGHFEITL YTNALVDPDG LVYWLPPAIY
160 170 180 190 200
RSACAIKVNY FPFDWQNCSM VFRSQTYSAN EIELKLTDEE NSVVEWIEID
210 220 230 240 250
PEAFTENGEW MIKHRPAKKM INEQFSRDEL DYQEIIFFLI IQRKPLFYVI
260 270 280 290 300
NIIVPCVLFS SLGLLVYFLP AKAGGQKCTM SIIILLAQTV FLFLIAKKVP
310 320 330 340 350
ETSQAVPLIG KYLMFVMSVT TITVMNCVVV LNVSLRTPNT HPMNDKVRKV
360 370 380 390 400
LLNILPRLLR MRMQRWSPQG GANGSTLPLR RRSSLGLIVK ADEYVMKTAR
410 420 430 440 450
SELMFSKLKE RDGLMRSALE KIKTTLEGDT VQDLSSSLAM ASPEVQQCVE
460 470 480 490 500
SCKHIAESTK RQNDFQSENE EWVLVARVID RLCFIAMAML FILGTVGIFL
510 520 530
MGHFNQAPSL PFPGDPKKYL PDMPPANATG
Length:530
Mass (Da):60,487
Last modified:April 16, 2014 - v1
Checksum:iDE91774D2DD4B8EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
APWO01055100 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSAMXT00000017199; ENSAMXP00000017199; ENSAMXG00000016691

Similar proteinsi

Entry informationi

Entry nameiW5LBI7_ASTMX
AccessioniPrimary (citable) accession number: W5LBI7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: March 28, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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