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Entry version 29 (31 Jul 2019)
Sequence version 1 (19 Mar 2014)
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Protein

MFS domain-containing protein

Gene
N/A
Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MFS domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStrongylocentrotus purpuratus (Purple sea urchin)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7668 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007110 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei20 – 42HelicalSequence analysisAdd BLAST23
Transmembranei48 – 67HelicalSequence analysisAdd BLAST20
Transmembranei137 – 154HelicalSequence analysisAdd BLAST18
Transmembranei166 – 187HelicalSequence analysisAdd BLAST22
Transmembranei194 – 215HelicalSequence analysisAdd BLAST22
Transmembranei221 – 242HelicalSequence analysisAdd BLAST22
Transmembranei254 – 275HelicalSequence analysisAdd BLAST22
Transmembranei300 – 324HelicalSequence analysisAdd BLAST25
Transmembranei331 – 350HelicalSequence analysisAdd BLAST20
Transmembranei356 – 377HelicalSequence analysisAdd BLAST22
Transmembranei389 – 411HelicalSequence analysisAdd BLAST23
Transmembranei417 – 436HelicalSequence analysisAdd BLAST20
Transmembranei507 – 524HelicalSequence analysisAdd BLAST18
Transmembranei536 – 557HelicalSequence analysisAdd BLAST22
Transmembranei564 – 584HelicalSequence analysisAdd BLAST21
Transmembranei616 – 636HelicalSequence analysisAdd BLAST21
Transmembranei648 – 669HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini262 – 763MFSInterPro annotationAdd BLAST502

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0255 Eukaryota
COG0477 LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
FTVFWNL

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083 Sugar_tr, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850 MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W4ZH03-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLISMVIGT EFVGPSRRAF VAIFISVSFS LGYLLLTFYA YLIRNWRYLL
60 70 80 90 100
LTLNMTFALF FFFYPFIPES VRWQISKGRY KRAEISIRKV AKINKVKLTD
110 120 130 140 150
DFFQQTNFYN SKDRQGDKKH DTNLTDLFRT PVLRKRMMIM IVIWMTNNLI
160 170 180 190 200
FYGFHLSTGS FGVDIYLSFV ISGVVEIVSV VLCIPLIEWF GRRYSFIASF
210 220 230 240 250
VIAGVASFIV IFVHAGAAKT SIAMVGKFGI AGSWAICGIY VIEILPTPTR
260 270 280 290 300
SAGVGICSMA SRIVAIATPL LLLLYDVWAP GPFVLQTIAA LFDLVCDRKY
310 320 330 340 350
LINLSQSLFF VGVLIGCVTF GAIADRFGRK VTLILCNIIF VLFGIGAAFS
360 370 380 390 400
PNYITFVVMR TIEAAACFGF ALTSYVIGTE FVGPSKRAFV SVMLTAVFPL
410 420 430 440 450
GYILLTFYAY LINNWRHLLL ALHLTFALYF FFYPFIPESV RWQISKGRYK
460 470 480 490 500
EAQATVKRVA KINKVKLTDD FFYQHNFYRT RETTNPERNH DPNLIDLFRT
510 520 530 540 550
PVLRKRMIVL IIVWMTNNLI FYGLHLSTGS FGVNIYLSFL ISAVVEVVAM
560 570 580 590 600
IICVPVIERV GRRYSLIACL TISGIASCIA IFIQRCNPSG LYKALSLCLM
610 620 630 640 650
SGCGMAFPPF LPAKALAYRF VALLLSSNFF CSSGLQHLYS TRSRLSDHII
660 670 680 690 700
VVSVFDVINL FTEFAIALFE HPSMSFVPTC NTKTVGFVRP LVIDSSHAFV
710 720 730 740 750
WSKRRPRFPA QWMTVPKSIS AQPVRSALRW AQKTMESPTI HICSVDKIRK
760
EDWAAFCIPK NMR
Length:763
Mass (Da):86,422
Last modified:March 19, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF07F1EDF844C8E83
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAGJ04116990 Genomic DNA No translation available.
AAGJ04116991 Genomic DNA No translation available.
AAGJ04116992 Genomic DNA No translation available.
AAGJ04116993 Genomic DNA No translation available.
AAGJ04116994 Genomic DNA No translation available.
AAGJ04116995 Genomic DNA No translation available.
AAGJ04116996 Genomic DNA No translation available.
AAGJ04116997 Genomic DNA No translation available.
AAGJ04116998 Genomic DNA No translation available.
AAGJ04116999 Genomic DNA No translation available.

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
SPU_027463-tr; SPU_027463-tr; SPU_027463

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGJ04116990 Genomic DNA No translation available.
AAGJ04116991 Genomic DNA No translation available.
AAGJ04116992 Genomic DNA No translation available.
AAGJ04116993 Genomic DNA No translation available.
AAGJ04116994 Genomic DNA No translation available.
AAGJ04116995 Genomic DNA No translation available.
AAGJ04116996 Genomic DNA No translation available.
AAGJ04116997 Genomic DNA No translation available.
AAGJ04116998 Genomic DNA No translation available.
AAGJ04116999 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiSPU_027463-tr; SPU_027463-tr; SPU_027463

Phylogenomic databases

eggNOGiKOG0255 Eukaryota
COG0477 LUCA
OMAiFTVFWNL

Family and domain databases

InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF00083 Sugar_tr, 2 hits
SUPFAMiSSF103473 SSF103473, 2 hits
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW4ZH03_STRPU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W4ZH03
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: July 31, 2019
This is version 29 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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