Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 36 (11 Dec 2019)
Sequence version 1 (19 Mar 2014)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStrongylocentrotus purpuratus (Purple sea urchin)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7668 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007110 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini45 – 106PHD-typeInterPro annotationAdd BLAST62
Domaini751 – 998Reverse transcriptaseInterPro annotationAdd BLAST248

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 41DisorderedSequence analysisAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili114 – 134Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 21PolarSequence analysisAdd BLAST21
Compositional biasi22 – 40PolyampholyteSequence analysisAdd BLAST19

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1075 Eukaryota
ENOG410Y65V LUCA

Identification of Orthologs from Complete Genome Data

More...
OMAi
ANESHRE

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit
3.60.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000477 RT_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14529 Exo_endo_phos_2, 1 hit
PF00078 RVT_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56219 SSF56219, 1 hit
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50878 RT_POL, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

W4YEI4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATRGRKTSV SRNTGRKGSV NEKTSATDKN EKHNQAQGRK ENKDNFSCGS
60 70 80 90 100
CGMIVLDDDA ALECELCNFW YHCTCQKIST NLYNTISELD EDDDGVHWYC
110 120 130 140 150
KTCNKTAKSM MTMMTSLKIQ HTKLESSVAE LREEMHECKT GCVQSHSELR
160 170 180 190 200
QEMRDMFDRQ GSSVMANPDQ IDKAETYEIM NKVMKERFDE IDEKEKRKTN
210 220 230 240 250
IIFFGVQESV SGEPATRKRD DETKIRAMID RLPNKSLEIR TLYRLGKKED
260 270 280 290 300
TKTRPLKVVM NNQAMRDEIL QKFRKVMYTN CDSVLNKREE VQTLILNTNP
310 320 330 340 350
DIIALTEVYP KNSPERIQPC ELNLDGYQMF LPERCKQNGR GVIMYLKNGI
360 370 380 390 400
AGSLVELDEN FDESVWVEIT IGESSLLIGC IYRSPSSVSE NNDNLCNLLK
410 420 430 440 450
RSCERRYTHY VAVGDFNYKE INWDNDTVNG SNLRGSHTFL TCVRDLFLYQ
460 470 480 490 500
HIHCNTRYRD GQDPSTLDLI FTKDEDTIHD IDTNPPLGKS DHVVLQFRLE
510 520 530 540 550
VNASSSEKEN SKKRSYYHGD YDEMRRRLEM IDWETDLNNL SGLEAWNHFE
560 570 580 590 600
KTMICCIEDL IPIRRVSQKK RPEWMTSSAK EAVRDKHKAW NKYSKRKTDT
610 620 630 640 650
NWSSYVDKRN AATLMTRNAK SDFESKIANE VKTNAKSFWK YVKSKTKTRT
660 670 680 690 700
GIPDLQMEDG NWVRNDQEKA DALNSFFGSI FTEEDLVNAP DMDPYQVESS
710 720 730 740 750
LNDVEFTEEV IVDILSKLDI DKSPGPDGLH SRVLKETCHQ IGKPLQMIFS
760 770 780 790 800
RLFKEGSVPA TWKEATVVPI FKKGKKSLPG NYRPVSLTSI ICKTMEKIIR
810 820 830 840 850
SKMIQHLELN HLFTDDQYGF RSGRSCSTQL TVVLEQWTKI LDDGHGIDCL
860 870 880 890 900
YLDFRKAFDS VPHQRLLTKV RANGMEGCLI KWIEKYLTGR SQRVVVNGKK
910 920 930 940 950
SETCEVTSGI PQGSVLGPVL FNIYINDLPS VAQNSTAKLF ADDTKLYRVV
960 970 980 990 1000
DNEEDAKLLQ QDLNDIVQWS SNWQLPFNEG KCKVIHYGKR NKKFAYTMEC
1010 1020 1030 1040 1050
PDGRKDVTTD EGMGEKDLGV LFDSDLSFCA HVADVSKRAN IKLGIIKRSF
1060 1070 1080 1090 1100
TSLGSSGMLQ LYKTIVRPTL EYCNAVWRPT YLKDQDLLEK VQQRATRLIP
1110 1120 1130 1140 1150
DVKHLSYEER LKTLKLPSLE YRRQRADLLQ IYKIMHGLEA VERNDIFEII
1160 1170 1180 1190 1200
KESRTRGHRL KIRKPRCKSK MRQMSFSVRS INNWNNLPEI AINASSINKF
1210 1220
KSELENHWKH HPLKYHPYQR ESNAVKRGT
Length:1,229
Mass (Da):141,979
Last modified:March 19, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2AB14BE00F3F1B6D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAGJ04103823 Genomic DNA No translation available.

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
SPU_014165-tr; SPU_014165-tr; SPU_014165

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGJ04103823 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblMetazoaiSPU_014165-tr; SPU_014165-tr; SPU_014165

Phylogenomic databases

eggNOGiKOG1075 Eukaryota
ENOG410Y65V LUCA
OMAiANESHRE

Family and domain databases

Gene3Di3.30.40.10, 1 hit
3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000477 RT_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF14529 Exo_endo_phos_2, 1 hit
PF00078 RVT_1, 1 hit
SUPFAMiSSF56219 SSF56219, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50878 RT_POL, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW4YEI4_STRPU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W4YEI4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: December 11, 2019
This is version 36 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again