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Protein
Submitted name:

MPN domain-containing protein

Gene

MPND

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
MPN domain-containing proteinImported
Gene namesi
Name:MPNDImported
Synonyms:FLJ14981Imported
ORF Names:hCG_2004608Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000008382.15
HGNCiHGNC:25934 MPND

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000008382

PTM / Processingi

Proteomic databases

MaxQBiW4VSR2
PRIDEiW4VSR2

Expressioni

Gene expression databases

BgeeiENSG00000008382 Expressed in 143 organ(s), highest expression level in liver
ExpressionAtlasiW4VSR2 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiW4VSR2, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini272 – 407MPNInterPro annotationAdd BLAST136

Phylogenomic databases

GeneTreeiENSGT00530000063766

Family and domain databases

InterProiView protein in InterPro
IPR000555 JAMM/MPN+_dom
IPR037518 MPN
PfamiView protein in Pfam
PF01398 JAB, 1 hit
PROSITEiView protein in PROSITE
PS50249 MPN, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

W4VSR2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPEPLSPA GGAGEEAPEE DEDEAEAEDP ERPNAGAGGG RSGGGGSSVS
60 70 80 90 100
GGGGGGGAGA GGCGGPGGAL TRRAVTLRVL LKDALLEPGA GVLSIYYLGK
110 120 130 140 150
KFLGDLQPDG RIMWQETGQT FNSPSAWATH CKKLVNPAKK SGCGWASVKY
160 170 180 190 200
KGQKLDKYKA TWLRLHQLHT PATAADESPA SEGEEEELLM EEEEEDVLAG
210 220 230 240 250
VSAEDKSRRP LGKSPSEPAH PEATTPGKRV DSKIRVPVRY CMLGSRDLAR
260 270 280 290 300
NPHTLVEVTS FAAINKFQPF NVAVSSNVLF LLDFHSHLTR SEVVGYLGGR
310 320 330 340 350
WDVNSQMLTV LRAFPCRSRL GDAETAAAIE EEIYQSLFLR GLSLVGWYHS
360 370 380 390 400
HPHSPALPSL QDIDAQMDYQ LRLQGSSNGF QPCLALLCSP YYSGNPGPES
410 420 430 440 450
KISPFWVMPP PEQRPSDYGI PMDVEMAYVQ DSFLTNDILH EMMLLVEFYK
460 470 480 490 500
GSPDLVRLQE PWSQEHTYLD KLKISLASRT PKDQSLCHVL EQVCGVLKQG

S
Length:501
Mass (Da):54,160
Last modified:March 19, 2014 - v1
Checksum:iB5DBA18A689E7490
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8N594MPND_HUMAN
MPN domain-containing protein
MPND
471Annotation score:
M0R189M0R189_HUMAN
MPN domain-containing protein
MPND
503Annotation score:
M0R044M0R044_HUMAN
MPN domain-containing protein
MPND
419Annotation score:
M0R0F2M0R0F2_HUMAN
MPN domain-containing protein
MPND
469Annotation score:
M0QXC4M0QXC4_HUMAN
MPN domain-containing protein
MPND
109Annotation score:
M0QXK5M0QXK5_HUMAN
MPN domain-containing protein
MPND
121Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007292 Genomic DNA No translation available.
CH471139 Genomic DNA Translation: EAW69231.1
RefSeqiNP_001287791.1, NM_001300862.1
UniGeneiHs.321689

Genome annotation databases

EnsembliENST00000599840; ENSP00000471735; ENSG00000008382
GeneIDi84954
UCSCiuc060rwd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007292 Genomic DNA No translation available.
CH471139 Genomic DNA Translation: EAW69231.1
RefSeqiNP_001287791.1, NM_001300862.1
UniGeneiHs.321689

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiW4VSR2, 1 interactor

Proteomic databases

MaxQBiW4VSR2
PRIDEiW4VSR2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000599840; ENSP00000471735; ENSG00000008382
GeneIDi84954
UCSCiuc060rwd.1 human

Organism-specific databases

CTDi84954
EuPathDBiHostDB:ENSG00000008382.15
HGNCiHGNC:25934 MPND
OpenTargetsiENSG00000008382
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000063766

Miscellaneous databases

ChiTaRSiMPND human
GenomeRNAii84954

Gene expression databases

BgeeiENSG00000008382 Expressed in 143 organ(s), highest expression level in liver
ExpressionAtlasiW4VSR2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000555 JAMM/MPN+_dom
IPR037518 MPN
PfamiView protein in Pfam
PF01398 JAB, 1 hit
PROSITEiView protein in PROSITE
PS50249 MPN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiW4VSR2_HUMAN
AccessioniPrimary (citable) accession number: W4VSR2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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