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Protein

Conotoxin Vc7.2

Gene
N/A
Organism
Conus victoriae (Queen Victoria cone)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Vc7.2Curated
Alternative name(s):
H_Vc7.21 PublicationImported
OrganismiConus victoriae (Queen Victoria cone)
Taxonomic identifieri319920 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaNeogastropodaConoideaConidaeConusCylinder

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
PropeptideiPRO_000043942723 – 49CuratedAdd BLAST27
PeptideiPRO_500485099650 – 74Conotoxin Vc7.2Add BLAST25

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi53 ↔ 63By similarity
Disulfide bondi58 ↔ 68By similarity
Disulfide bondi62 ↔ 73By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.1 Publication

Family & Domainsi

Domaini

The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.Curated
The cysteine framework is VI/VII (C-C-CC-C-C).1 Publication

Sequence similaritiesi

Belongs to the conotoxin H superfamily.1 Publication

Keywords - Domaini

Knottin, Signal

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

W4VS16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNTAGRLLLL CLVLGLVFES LGIPVADDLE ADRDTDPDEK DPSVHNYWRN
60 70
VNCGGVPCKF GCCREDRCRE IDCD
Length:74
Mass (Da):8,258
Last modified:March 19, 2014 - v1
Checksum:iC3EF6CE505CB65D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAIH01000011 mRNA Translation: JAB84706.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAIH01000011 mRNA Translation: JAB84706.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiH72_CONVC
AccessioniPrimary (citable) accession number: W4VS16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2017
Last sequence update: March 19, 2014
Last modified: October 10, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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