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Entry version 17 (11 Dec 2019)
Sequence version 1 (19 Mar 2014)
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Protein
Submitted name:

Putative retrovirus-related pol polyprotein from transposon tnt

Gene
N/A
Organism
Corethrella appendiculata
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative retrovirus-related pol polyprotein from transposon tntImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCorethrella appendiculataImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1370023 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaChaoboridaeCorethrella

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini200 – 214CCHC-typeInterPro annotationAdd BLAST15
Domaini442 – 610Integrase catalyticInterPro annotationAdd BLAST169

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni218 – 243DisorderedSequence analysisAdd BLAST26
Regioni699 – 741DisorderedSequence analysisAdd BLAST43
Regioni757 – 781DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi221 – 243PolarSequence analysisAdd BLAST23
Compositional biasi699 – 727PolarSequence analysisAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025724 GAG-pre-integrase_dom
IPR001584 Integrase_cat-core
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR013103 RVT_2
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13976 gag_pre-integrs, 1 hit
PF00665 rve, 1 hit
PF07727 RVT_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit
SSF57756 SSF57756, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994 INTEGRASE, 1 hit
PS50158 ZF_CCHC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

W4VRP2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
KLTGRDNFNN WKIAVQALLE LDDLFSETIE ADIPAAAAKE RKAKAKLILS
60 70 80 90 100
IDPICYVHIQ GASTAKEIWK RLSDAYDDNG LTRRVGLLRK LITTNLSSCG
110 120 130 140 150
SMEIYVNQII TTAHALNTIG FIVDEEWVGT LLLAGLPEEY RPMIMGLESS
160 170 180 190 200
GQKISGDLVK MKLLQEIPVG VTETAFATNK MKNHQSYEQS SRVGPKKHIR
210 220 230 240 250
CSRCNKFGHI ARKCFSRSNR RHDNNNNNYN NSSNNGSSNS GPPKSFSAFS
260 270 280 290 300
ALSTFQSKDD NWYIDSAATK HLTKDSNMLL NKQKFEGSVM AANGETIQIT
310 320 330 340 350
EIGSAAIHPV CSNECINIEK VHYLPGLAVN LLSVSEIVNR GHTIVFNNKG
360 370 380 390 400
AEITNSNGDL LVTATNKDGL FQVDQQREMA LYTKTNSYEL WHRRMGHLNS
410 420 430 440 450
SSLMALRNGL AEGVNYVKTE PQDCKICPLG KQTREKFSKC GSRASEILQI
460 470 480 490 500
VHSDICGPME TESIGGSRYF LTFIDDKSRK FFIYFLKTKS QWEVTEKFEQ
510 520 530 540 550
FMQLAERQSG CKIKILRTDN GTEYTNRHFQ KILSKNGIIH QTTNSYTPQQ
560 570 580 590 600
NGLAERANRS ITEKARCLLA DANMTKGFWA EAVHYAVYLL NRSPAKGTSK
610 620 630 640 650
TPYEVWCGKK PNLNHIRIFG TTVMALIPKQ LRRKLDMKSR QGKLVGYDEF
660 670 680 690 700
TKGYRIYDSD KKEVFISRDV KFINEGVILQ QQQQQHQQQP LIDIPIGEES
710 720 730 740 750
QHSENSDTSS SSSTSSLALP EQNQSGQSLR RSKRERRLPG KYNQFYVETR
760 770 780 790 800
NLPSFSHFQR NHAGASPDAD RGNSNLSSSS VSTITDAQRE IDSTFLAPLS
810 820 830 840 850
NLNRPVVNKQ QEFKHSDSGR RPQGKYPHTL VKNVDTSLNF SHSDDPVTPE
860 870 880 890 900
EALSRPDADQ WRLAMEEEFQ SLISNDTWEL TDIPRGRNPI KCKWVFKAKK
910 920 930 940 950
DASGEIVRHK ARLVIKGYSQ RKGVDYIETY SPVVRYGSLR YLFALAAKLN
960 970 980 990 1000
LAVEQMDATT AFLQGELDEE IFMEQPPFYS KDSSKCCRLK KALYGLKQAS
1010 1020 1030 1040 1050
RVWNQKLEET LKRLGFQQSD YDTCVYFKSD GNRILIVAIY VDDLLIFSSC
1060 1070 1080 1090 1100
KNWIMDVKRQ LNTHFKMKEL GEASYCLGMK IIKTGDSITL DQEHYVKEIL
1110 1120 1130 1140 1150
TKFGMADCKP VTTPLNVSEK LSKADCPNTP EEIREMQNVP YREVIGCLMY
1160 1170 1180 1190 1200
LSQCTRPDIS FAVNKLSQFN SNPGMKHWLA AKHLLRYLQG TSSYKLTYHR
1210 1220 1230 1240 1250
ESNMDGIVGY CDADWAADID DRRSTSGFVF MSQGGAISWC SRKQQTVSLS
1260 1270 1280 1290 1300
SCEAEYMSLS SAVQEVLWWH GFSQQLNICA GKIKLFCDNQ SAIFLAGNKG
1310 1320 1330 1340 1350
YNPRTKHIDI RHHFVQDVLK QQLFLLSYVP TTQQVADGLT KSLDKVKVER
1360
CRKSMGVKVD YKG
Length:1,363
Mass (Da):154,280
Last modified:March 19, 2014 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8DF6CEB6526FCC15
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GANO01000660 mRNA Translation: JAB59211.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GANO01000660 mRNA Translation: JAB59211.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR025724 GAG-pre-integrase_dom
IPR001584 Integrase_cat-core
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR013103 RVT_2
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF13976 gag_pre-integrs, 1 hit
PF00665 rve, 1 hit
PF07727 RVT_2, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
SSF57756 SSF57756, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit
PS50158 ZF_CCHC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiW4VRP2_9DIPT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: W4VRP2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: December 11, 2019
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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